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Ileectomy-induceret galde Overaccumulation i mus tarmen
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Ileectomy-induceret galde Overaccumulation i mus tarmen

Article DOI: 10.3791/55728-v • 06:55 min • August 21st, 2017
August 21st, 2017 •
*1,2,3, 1,2, 1,2, *1,2
1Department of Medicine, Case Cardiovascular Research Institute, Case Western Reserve University, 2Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, 3Institute for Transformative Molecular Medicine, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center
* These authors contributed equally

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Tyndtarmen-afhængige galdesyre reabsorption og feedback hæmning af hepatisk galdesyre syntese er vigtigt for systemisk homøostase og sundhed. I denne undersøgelse beskriver vi en musemodel for ileal resektion at evaluere ileectomy-induceret galde malabsorption, overaccumulation og toksicitet i mus tarmen.

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Medicin sag 126 Ileectomy mus sygdom model væv meddelelse fibroblast vækstfaktor 15 (FGF15) galdesyre reabsorption kort tyktarm
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