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Journal / Chemistry / Sintesi in fase solida di [4,4] Spirocyclic ossime
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Sintesi in fase solida di [4,4] Spirocyclic ossime
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Sintesi in fase solida di [4,4] Spirocyclic ossime

Article DOI: 10.3791/58508-v • 05:15 min • February 6th, 2019
February 6th, 2019 •
1, 1, 1
1Department of Biology and Chemistry, Azusa Pacific University

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Qui presentiamo un protocollo per dimostrare un metodo efficiente per la sintesi di eterocicli spirocyclic. Sintesi in fase solida e rigenerante strategie del linker Michael utilizza il processo in cinque fasi. Generalmente difficili da sintetizzare, presentiamo un metodo personalizzabile per la sintesi di molecole spirocyclic altrimenti inaccessibili ad altri approcci moderni.

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Chimica problema 144 sintesi in fase solida rigenerazione del linker Michael cicloaddizione 1,3-dipolare intramolecolare spirocyclic eterocicli triciclici diastereoselettività intermedia alta
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