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JoVE Journal Neuroscience
A Protocol for Transcranial Photobiomodulation Therapy in Mice
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A Protocol for Transcranial Photobiomodulation Therapy in Mice

Article DOI: 10.3791/59076-v • 13:08 min • November 18th, 2018
November 18th, 2018 •
1,2, 3, 4,5,6, 1, 1, 7, 8,9,10, 1
1Neurosciences Research Center, Tabriz University of Medical Sciences, 2ProNeuroLIGHT LLC, 3LiteCure LLC, 4Department of Psychiatry, Harvard Medical School, 5Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, 6Center for Anxiety and Traumatic Stress Disorders, Department of Psychiatry, Massachusetts General Hospital, 7Research Institute for Applied Physics and Astronomy, University of Tabriz, 8Department of Medical Physics, Tabriz University of Medical Sciences, 9Department of Medical Bioengineering, Tabriz University of Medical Sciences, 10School of Medical Sciences, University of Aberdeen

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Summary
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Photobiomodulation therapy is an innovative noninvasive modality for the treatment of a wide range of neurological and psychiatric disorders and can also improve healthy brain function. This protocol includes a step-by-step guide to performing brain photobiomodulation in mice by transcranial light delivery, which can be adapted for use in other laboratory rodents.

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Transcranial Photobiomodulation Therapy Mice Experimental Protocol Red Laser Laser Probe Brain Tissue Skull Scalp Laser Light Transmission Spatial Learning Memory Functions Barnes Maze Task Hippocampal ATP Levels Spectrophotometric Method Cortical Surface Aged Mice Transcranial Red Laser Treatment Neurological Disorders Psychiatric Disorders Brain Function
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