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Direct Intrabronchial Administration å forbedre selektiv agent deponering innenfor Mouse Lung
JoVE Journal
Medicine
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JoVE Journal Medicine
Direct Intrabronchial Administration to Improve the Selective Agent Deposition Within the Mouse Lung
DOI:

07:10 min

May 20, 2019

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Chapters

  • 00:04Title
  • 01:09Non-Operative Intratracheal (IT) Intubation
  • 02:16Intrabronchial (IB) Approach to Distal Right Lung Selective Lobar Cannulation
  • 03:00IB Approach to Distal Left Lung Selective Segmental Cannulation
  • 03:44Right Entire Lung Administration
  • 04:37Left Entire Lung Administration
  • 05:31Results: Representative Effects of Direct IB Selective Agent Administration to Whole Mouse Lung
  • 06:49Conclusion

Summary

Automatic Translation

Intratrakeal (IT) administrering av eksperimentelle midler hos mus resulterer ofte i asymmetrisk levering til de opp-lungene.  I denne rapporten beskriver vi en direkte intrabronchial (IB) for å kannelerer hver lunge i levende mus ikke-operativt.  Denne tilnærmingen kan brukes til å selektivt administrere agenter til en lunge eller kan tilpasses for å forbedre symmetrisk agent levering til begge lungene.

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