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JoVE Journal
Immunology and Infection

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Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods
 

Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods

Article doi: 10.3791/60421
December 21st, 2019

Summary December 21st, 2019

We present a general protocol for identifying short stretches of homologous host-pathogen protein sequences (SSHHPS) embedded in the viral polyprotein. SSHHPS are recognized by viral proteases and direct the targeted destruction of specific host proteins by several Group IV viruses.

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