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Developmental Biology

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JoVE Journal Developmental Biology
En Drosophila Model til undersøgelse Sår-induceret Polyploidization
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En Drosophila Model til undersøgelse Sår-induceret Polyploidization

Article DOI: 10.3791/61252-v • 07:27 min • June 9th, 2020
June 9th, 2020 •
*1, *1, 2, 1, 1
1Biology Department, Boston College, 2Graduate School of Biomedical Sciences and Engineering and Kathryn W. Davis Center for Regenerative Biology and Medicine, MDI Biological Laboratory, University of Maine
* These authors contributed equally

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Sår-induceret polyploidisering er en bevaret væv reparation strategi, hvor cellerne vokser i størrelse i stedet for at dividere for at kompensere for celletab. Her er en detaljeret protokol om, hvordan man bruger frugtfluen som model til at måle ploidy og dens genetiske regulering i epitelsår reparation.

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Udviklingsmæssige Biologi sårheling væv reparation endoreplering polyploidy Myc Drosophila
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