Creation of Abdominal Adhesions in Mice

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Medicine

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Medicine

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JoVE Journal Medicine

Creation of Abdominal Adhesions in Mice

DOI:

10.3791/54450-v

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06:44 min

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August 27, 2016

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Clement D. Marshall, Michael S. Hu, Tripp Leavitt, Leandra A. Barnes, Alexander T.M. Cheung, Samir Malhotra, H. Peter Lorenz, Michael T. Longaker

¹Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery,Stanford University School of Medicine

Chapters

00:05Title
01:00Abdominal Adhesion Creation
04:36Abdominal Incision Closure
05:45Results: Representative Abdominal Adhesion Analyses
06:15Conclusion

Summary

Automatic Translation

Abdominal adhesions that form after surgery are a major cause of pain, infertility, and hospitalization and reoperation for small bowel obstruction. Our surgical procedure for creating abdominal adhesions in mice is a reliable tool to study the mechanisms underlying the formation of adhesions.

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