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Microscopische observatie van lymfocytendynamiek in rat Peyer's patches
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Microscopische observatie van lymfocytendynamiek in rat Peyer's patches

Article DOI: 10.3791/61568-v • 06:37 min • June 25th, 2020
June 25th, 2020 •
1,2, 1, 2, 1, 2, 1
1Department of internal medicine, National Defense Medical College, 2Division of Gastroenterology and Hepatology, Department of Internal Medicine, Jikei University School of Medicine

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Hier beschrijven we een nauwkeurige methode voor het verzamelen van thoracale kanaallymfocyten en het observeren van de migratie van darm-tropenlymfocyten in de patches van rat Peyer gedurende 3 uur met behulp van time-lapse fotografie. Deze techniek kan verduidelijken hoe de dynamiek van lymfocyten wordt beïnvloed onder inflammatoire omstandigheden.

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Geneeskunde 2-accetyl-4-tetrahydroxybutyl imidazol (THI) sphingosine-1-fosfaat (S1P) S1P lyase (SPL) Peyer's patches (PPs) high endothelial venules (HEVs) lymfocytenmigratie
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