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Examining Muscle Regeneration in Zebrafish Models of Muscle Disease
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Chapters
- 00:04Introduction
- 00:41Live Embryo Genotyping
- 02:58Muscle Injury
- 03:55Muscle Regeneration Quantification
- 05:54Results: Representative Muscle Regeneration Analysis in Wildtype and Lama2 Deficient Zebrafish Larvae
- 07:10Conclusion
Skeletal muscle regeneration is driven by tissue resident muscle stem cells, which are impaired in many muscle diseases such as muscular dystrophy, and this results in the inability of muscle to regenerate. Here, we describe a protocol that allows the examination of muscle regeneration in zebrafish models of muscle disease.
