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JoVE Journal
Genetics

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In-Nucleus Hi-C i Drosophila celler
 
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In-Nucleus Hi-C i Drosophila celler

Article DOI: 10.3791/62106-v
September 15th, 2021

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Summary September 15th, 2021

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Genomet är organiserat i kärnrummet i olika strukturer som kan avslöjas genom kromosomkonformationsfångstteknik. Hi-C-metoden i nukleus ger en genomomfattande samling kromatininteraktioner i Drosophila-cellinjer, som genererar kontaktkartor som kan utforskas vid megabasupplösning på begränsningsfragmentnivå.

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