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Journal / Genetics / In-Nucleus Hi-C i Drosophila celler
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JoVE Journal Genetics
In-Nucleus Hi-C i Drosophila celler
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In-Nucleus Hi-C i Drosophila celler

Article DOI: 10.3791/62106-v • 11:58 min • September 15th, 2021
September 15th, 2021 •
1, 1, 1, 1
1Departamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México

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Genomet är organiserat i kärnrummet i olika strukturer som kan avslöjas genom kromosomkonformationsfångstteknik. Hi-C-metoden i nukleus ger en genomomfattande samling kromatininteraktioner i Drosophila-cellinjer, som genererar kontaktkartor som kan utforskas vid megabasupplösning på begränsningsfragmentnivå.

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Genetik Utgåva 175 Chromatin Genome 3D-organisation fack topologiskt associera domäner
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