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Journal / Cancer Research / Samkultur av Glioblastoma stamceller på mønstrede …
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JoVE Journal Cancer Research
Samkultur av Glioblastoma stamceller på mønstrede nevroner for å studere migrasjon og cellulære interaksjoner
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Samkultur av Glioblastoma stamceller på mønstrede nevroner for å studere migrasjon og cellulære interaksjoner

Article DOI: 10.3791/62213-v • 10:08 min • February 24th, 2021
February 24th, 2021 •
1, 2,3, 4, 1, *2, *4
1University Bordeaux, INSERM, LAMC, U1029, 33600, Pessac, France, 2Univ. Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience, IINS, UMR 5297, Bordeaux, France, 3Alvéole, Bordeaux, France, 4University Bordeaux, CNRS, IBGC, UMR5095, 33000, Bordeaux, France
* These authors contributed equally

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Her presenterer vi en brukervennlig samkulturanalyse for å analysere glioblastom (GBM) migrasjon på mønstrede nevroner. Vi utviklet en makro i FiJi-programvare for enkel kvantifisering av GBM cellemigrering på nevroner, og observerte at nevroner endrer GBM-celleinvasiv kapasitet.

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Kreftforskning Utgave 168 glioblastom pasientavledet celle sfæroid invasjon nevroner avanserte in vitro-modeller
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