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Neuroscience

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JoVE Journal Neuroscience
Optimización del modelo de ratón de oclusión de venas retinianas para limitar la variabilidad
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Optimización del modelo de ratón de oclusión de venas retinianas para limitar la variabilidad

Article DOI: 10.3791/62980-v • 07:23 min • August 6th, 2021
August 6th, 2021 •
*1, *2, 1, 1, 1,3,4
1Department of Pathology & Cell Biology; Vagelos College of Physicians and Surgeons, Columbia University, 2Department of Molecular Pharmacology and Therapeutics; Vagelos College of Physicians and Surgeons, Columbia University, 3Department of Neurology; Vagelos College of Physicians and Surgeons, Columbia University, 4The Taub Institute for Research on Alzheimer’s Disease and the Aging Brain; Vagelos College of Physicians and Surgeons, Columbia University
* These authors contributed equally

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Aquí, describimos un protocolo optimizado para la oclusión de la vena retiniana utilizando rosa de bengala y un sistema de microscopio de imágenes de retina guiado por láser con recomendaciones para maximizar su reproducibilidad en cepas modificadas genéticamente.

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Neurociencia Número 174
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