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Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording
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1Department of Electronic and Electrical Engineering,Ewha Womans University, 2Graduate Program in Smart Factory,Ewha Womans University, 3Department of Electrical and Computer Engineering,Seoul National University, 4Graduate School of Engineering Practice,Seoul National University, 5Department of Brain and Cognitive Sciences,Ewha Womans University
Chapters
- 00:04Introduction
- 01:13Preparation of an Optrode Array
- 01:39Presurgical Preparation of Animal and Implantation Surgery
- 03:45Setting Parameters and Conducting Optogenetic Stimulation, Electrophysiological Recording, and Data Analysis
- 04:55Results: Electrophysiological Recording
- 05:40Conclusion
Here, we present the fabrication method of an optrode system with optical fibers for light delivery and an electrode array for neural recording. In vivo experiments with transgenic mice expressing channelrhodopsin-2 show the feasibility of the system for simultaneous optogenetic stimulation and electrophysiological recording.
