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JoVE Journal Medicine
O-Ring-Aortenband versus traditionelle transversale Aortenverengung zur Modellierung von Drucküberlastung-induzierter Herzhypertrophie
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O-Ring-Aortenband versus traditionelle transversale Aortenverengung zur Modellierung von Drucküberlastung-induzierter Herzhypertrophie

Article DOI: 10.3791/64455-v • 09:24 min • October 6th, 2022
October 6th, 2022 •
1, 1, 2, 1, 1, 1, 2, 2, 1
1Department of Internal Medicine III, German Centre for Cardiovascular Research, University Hospital Kiel, Partner Site Hamburg/Kiel/Lübeck, 2Internal Medicine III, German Centre for Cardiovascular Research, University Hospital Heidelberg, Partner Site Heidelberg/Mannheim

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Das vorliegende Protokoll beschreibt eine neue Technik der Aortenbandbildung bei Mäusen, um eine Drucküberlastung der Herzhypertrophie zu induzieren. Zum Banderolieren wird ein Gummiring mit festem Innendurchmesser verwendet. Diese neue Technik verspricht weniger Varianz und reproduzierbarere Daten für zukünftige Experimente.

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Medizin Ausgabe 188
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