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JoVE Journal Bioengineering
Micro-engineering 3D collageen hydrogels met lange-afstand vezeluitlijning
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Micro-engineering 3D collageen hydrogels met lange-afstand vezeluitlijning

Article DOI: 10.3791/64457-v • 07:12 min • September 7th, 2022
September 7th, 2022 •
1, 1, 1, 1, 1, 1, 1, 1
1Department of Biomedical Engineering, Kate Gleason College of Engineering, Rochester Institute of Technology

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Dit protocol demonstreert het gebruik van een microfluïdisch kanaal met veranderende geometrie langs de vloeistofstroomrichting om extensieve spanning (stretching) te genereren om vezels uit te lijnen in een 3D-collageenhydrogel (< 250 μm dik). De resulterende uitlijning strekt zich uit over enkele millimeters en wordt beïnvloed door de extensieve reksnelheid.

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