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JoVE Journal Bioengineering
Noninvasive and Invasive Renal Hypoxia Monitoring in a Porcine Model of Hemorrhagic Shock
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Noninvasive and Invasive Renal Hypoxia Monitoring in a Porcine Model of Hemorrhagic Shock

Article DOI: 10.3791/64461-v • 07:48 min • October 28th, 2022
October 28th, 2022 •
1, 2,3, 1,4, 4,5
1Department of Biomedical Engineering, University of Utah, 2Department of Emergency Medicine, University of Utah, 3Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, 4Department of Anesthesiology, University of Utah, 5Geriatric Research, Education, and Clinical Centre, VAMC

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Summary
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Presented here is a protocol to measure renal oxygenation in the medulla and noninvasive urine oxygen partial pressure in a hemorrhagic shock porcine model to establish urine oxygen partial pressure as an early indicator of acute kidney injury (AKI) and a novel resuscitative endpoint.

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Noninvasive Renal Hypoxia Monitoring Invasive Renal Hypoxia Monitoring Porcine Model Hemorrhagic Shock Acute Kidney Injury Urine Oxygen Partial Pressure Traumatic Hemorrhagic Shock Translatable To Humans Puncture Sites Chlorhexidine Scrub Alcohol Scrub Sterile Draping Local Pain Relief Lidocaine Infiltration Ultrasound Guidance Seldinger Technique External Jugular Vein Catheter Medication Infusion Central Venous Pressure Monitoring Resuscitative Endovascular Occlusion Of The Aorta (REBOA) Femoral Artery Sheath Disposable Pressure Transducer Midline Laparotomy PuO2 Measurement At The Outlet Of The Bladder
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