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Facile Preparation and Photoactivation of Prodrug-Dye Nanoassemblies
JoVE Journal
Medicine
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JoVE Journal Medicine
Facile Preparation and Photoactivation of Prodrug-Dye Nanoassemblies
DOI:

08:54 min

February 17, 2023

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Chapters

  • 00:04Introduction
  • 00:37Preparation of IR783/BC Nanoparticles by the Flash Precipitation Method
  • 02:52Characterization of IR783/BC Nanoparticles
  • 04:47Photoactivation of IR783/BC Nanoparticles
  • 06:24Results: Fabrication and Characterization of a Photoresponsive Prodrug-Dye Nano Assembly
  • 08:27Conclusion

Summary

Automatic Translation

This protocol describes the fabrication and characterization of a photoresponsive prodrug-dye nanoassembly. The methodology for drug release from the nanoparticles by light-triggered disassembly, including the light irradiation setup, is explicitly described. The drugs released from the nanoparticles following light irradiation exhibited excellent anti-proliferation effects on human colorectal tumor cells.

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