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Evaluating Quantitative Tumor Cell Killing by CAR-Expressing Jurkat Cells
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High-Throughput Screening of CAR T-Cell Constructs for Enhanced Cytotoxicity and Immunologic Memory (Video) | JoVE
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Cancer Research
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JoVE Journal Cancer Research
Rapid In Vitro Cytotoxicity Evaluation of Jurkat Expressing Chimeric Antigen Receptor using Fluorescent Imaging

High-Throughput Screening of CAR T-Cell Constructs for Enhanced Cytotoxicity and Immunologic Memory (Video) | JoVE

Evaluating Quantitative Tumor Cell Killing by CAR-Expressing Jurkat Cells

DOI:
10.3791/65560-v

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01:44 min

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October 27, 2023

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, , , , , ,
1Department of Radiation Oncology,University of Kansas Cancer Center, 2Department of Cancer Biology,University of Kansas Cancer Center, 3BioEngineering Program,University of Kansas, 4Department of Pathology and Laboratory Medicine,University of Kansas Medical Center, 5University of Kansas Cancer Center, 6Kansas Institute for Precision Medicine,University of Kansas Medical Center

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Keywords: CAR T-cellsJurkat CellsCytotoxicityFluorescent ImagingHigh-throughput ScreeningCAR Construct OptimizationCancer Immunotherapy

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