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Capturing Oral Submucous Fibrosis Tissue Samples for Spatial-Omics Analysis

Article DOI: 10.3791/65890-v • 01:46 min • August 11th, 2023
August 11th, 2023 •
1,2, 3, 1,2, 1,2
1Department of Oral Pathology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, 2Research Unit of Precision Pathologic Diagnosis in Tumors of the Oral and Maxillofacial Regions, Chinese Academy of Medical Sciences (2019RU034), 3Central Laboratory, Peking University School and Hospital of Stomatology

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Aislamiento Células Información Morfológica Información Espacial Muestras de Fibrosis Submucosa Oral Microdisección por Captura Láser Trastorno Potencialmente Maligno Atrofia Epitelio Fibrosis Lámina Propia Submucosa Portaobjetos Histopatológicos Displasia Epitelial Fibroblastos Senescentes Transformación Maligna Mecanismos Moleculares Heterogeneidad Carcinoma Oral de Células Escamosas Mecanismos Moleculares Específicos Portaobjetos de Tejido Fijados en Formalina Incluidos en Parafina Microscopio Displasia a Microescala Tejido Tejido epitelial atrófico Tejido subepitelial fibrótico Secuenciación del genoma Secuenciación del transcriptoma Datos genómicos Datos ómicos
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