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Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive
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Bioengineering
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JoVE Journal Bioengineering
Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive

Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive

DOI:
10.3791/50609-v

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06:40 min

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September 27, 2013

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, , , , , , , ,
1Materials Engineering Division,Lawrence Livermore National Laboratory, 2UCSF Center for Integrative Neuroscience and the Department of Physiology,University of California, San Francisco

Chapters

  • 00:05Title
  • 01:19Assembly of Probe to Stiffener
  • 03:13Insertion and Extraction in Agarose Gel
  • 05:30Results: Neural Probes
  • 06:10Conclusion

Summary

Automatic Translation

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Insertion of flexible neural microelectrode probes is enabled by attaching probes to rigid stiffeners with polyethylene glycol (PEG). A unique assembly process ensures uniform and repeatable attachment. After insertion into tissue, the PEG dissolves and the stiffener is extracted. An in vitro test method evaluates the technique in agarose gel.

Tags

Flexible Neural ProbesRigid StiffenersBiodissolvable AdhesiveMicroelectrode ArraysNeural Interface DevicesFlip-chip BondingIn Vitro TestAgarose Gel ModelCortex Recording

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