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Arricchimento per chemioresistente Ovarian Cancer Stem Cells da linee cellulari umane

Article DOI: 10.3791/51891-v • 11:50 min • September 10th, 2014
September 10th, 2014 •
1, 1, 1, 1
1Department of Biochemistry and Molecular Biology, Indiana University School of Medicine

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Le cellule staminali tumorali (CSC) sono implicati nel tumore recidiva a causa di chemioresistenza. Abbiamo ottimizzato un protocollo per la selezione ed espansione di cellule staminali tumorali da linee cellulari di carcinoma ovarico. Trattando le cellule con il cisplatino chemioterapico e coltura in una cellula staminale promuovere media che arricchiscono per le culture CSC non aderenti.

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Medicina cellule staminali tumorali marcatori di cellule staminali cancro ovarico chemioresistenza cisplatino la progressione del cancro
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