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Fastsettelse av den Relative styrken av en Anti-TNF monoklonalt antistoff (mAb) av Neutralizing TNF bruker en I Vitro Bioanalytical metode
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Fastsettelse av den Relative styrken av en Anti-TNF monoklonalt antistoff (mAb) av Neutralizing TNF bruker en I Vitro Bioanalytical metode

Article DOI: 10.3791/55376-v • 16:07 min • September 16th, 2017
September 16th, 2017 •
1, 1, 1, 1, 1, 2
1Research and Development, Probiomed, 2Bioprocess Research and Development Unit, Instituto Politecnico Nacional

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En protokoll for fastsettelse av relativ anti-apoptotisk aktiviteten til en anti-TNFα mAb en nøytralisering mekanisme med WEHI 164 celler er presentert her. Denne protokollen er nyttige for sammenligning nøytralisering styrken av ulike molekyler med samme biologiske funksjonalitet.

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Medisin problemet 127 apoptose nøytralisering analysen tumor nekrose faktor alpha anti-TNFα mAb biocomparability
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