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Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer’s Disease and Mild Cognitive Impairment
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JoVE Journal Medicine
Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer’s Disease and Mild Cognitive Impairment

Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer’s Disease and Mild Cognitive Impairment

DOI:
10.3791/56015-v

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08:43 min

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August 07, 2017

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, , , , , ,
1Zhejiang Chinese Medical University, 2Department of Psychiatry,Zhejiang Provincial People’s Hospital, 3Department of Radiology,Zhejiang Provincial People’s Hospital

Chapters

  • 00:05Title
  • 01:57Data Preprocessing
  • 03:54Directed Connectivity Analysis
  • 06:38Results: GCA with PCC Shows Differences in Directed Connectivity Between the Alzheimer’s Disease (AD), Mild Cognitive Impairment (MCI), and Control Groups
  • 07:28Conclusion

Summary

Automatic Translation

Automatic Translation

Based on resting-state functional magnetic resonance imaging with Granger causality analysis, we investigated the alterations in the directed functional connectivity between the posterior cingulate cortex and whole brain in patients with Alzheimer's Disease (AD), patients with Mild Cognitive Impairment (MCI), and healthy controls.

Tags

Granger Causality AnalysisDirected Functional ConnectivityAlzheimer’s DiseaseMild Cognitive ImpairmentFMRIPCCDiagnosisProgressionEEGPreprocessingDicomToNiftiSlice TimingRealignmentNormalizationSegmentationSmoothing

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