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Chapters
- 00:04Title
- 00:51Canine Angiography
- 04:06Canine Carotid Artery Occlusion
- 06:19Results: Representative Carotid Blood Flow and Post Occlusion Imaging
- 07:34Conclusion
Here, we present the modifications necessary to a well characterized and commonly used small animal ferric chloride-induced (FeCl3) carotid artery injury model for use in a large animal vascular injury model. The resulting model can be utilized for pre-clinical trial assessment of both prophylactic and thrombolytic pharmacological and mechanical interventions.
Tags
Ferric Chloride-induced Canine Carotid Artery ThrombosisLarge Animal ModelVascular InjuryThrombosisPhysiological ParametersComplete Blood CountPlatelet FunctionAngiographyHistologySerial Blood SamplingCarotid ArteryOcclusive ThrombusFemoral ArteryGuide WireAngiographic CatheterContrast InjectionBlood Pressure Measurements
