Alfred E. Chang

Publications

• OK-432 Synergizes with IFN-γ to Confer Dendritic Cells with Enhanced Antitumor Immunity
  Immunology and Cell Biology. Dec, 2013  |   Pubmed ID: 24296809
• Cancer Immunotherapy: Current Status and Future Directions
  Surgical Oncology Clinics of North America. Oct, 2013  |   Pubmed ID: 24012398
• IL-17A Promotes Immune Cell Recruitment in Human Esophageal Cancers and the Infiltrating Dendritic Cells Represent a Positive Prognostic Marker for Patient Survival
  Journal of Immunotherapy (Hagerstown, Md. : 1997). Oct, 2013  |   Pubmed ID: 23994890
• Cytokine-induced Killer (CIK) Cells Bound with Anti-CD3/anti-CD133 Bispecific Antibodies Target CD133(high) Cancer Stem Cells in Vitro and in Vivo
  Clinical Immunology (Orlando, Fla.). Oct, 2013  |   Pubmed ID: 23994769
• Effects of Tumor Irradiation on Host T-regulatory Cells and Systemic Immunity in the Context of Adoptive T-cell Therapy in Mice
  Journal of Immunotherapy (Hagerstown, Md. : 1997). Feb, 2013  |   Pubmed ID: 23377667
• Targeting Cancer Stem Cells Via Dendritic-cell Vaccination
  Oncoimmunology. Nov, 2012  |   Pubmed ID: 23243607
• Interleukin-6 Inhibits Regulatory T Cells and Improves the Proliferation and Cytotoxic Activity of Cytokine-induced Killer Cells
  Journal of Immunotherapy (Hagerstown, Md. : 1997). May, 2012  |   Pubmed ID: 22495391
• Cancer Stem Cell Vaccination Confers Significant Antitumor Immunity
  Cancer Research. Apr, 2012  |   Pubmed ID: 22473314
• Characterization of Bridging Integrator 1 (BIN1) As a Potential Tumor Suppressor and Prognostic Marker in Hepatocellular Carcinoma
  Molecular Medicine (Cambridge, Mass.). 2012  |   Pubmed ID: 22281836
• Is Duct Excision Still Necessary for All Cases of Suspicious Nipple Discharge?
  The Breast Journal. Mar-Apr, 2012  |   Pubmed ID: 22211878
• B Lymphocytes As Effector Cells in the Immunotherapy of Cancer
  Journal of Surgical Oncology. Mar, 2012  |   Pubmed ID: 21898417
• Is a Level III Dissection Necessary for a Positive Sentinel Lymph Node in Melanoma?
  Journal of Surgical Oncology. Mar, 2012  |   Pubmed ID: 21882199
• Validation of Statistical Predictive Models Meant to Select Melanoma Patients for Sentinel Lymph Node Biopsy
  Annals of Surgical Oncology. Jan, 2012  |   Pubmed ID: 21822550
• 癌免疫療法の重要なハードルを定義します。
  Journal of Translational Medicine. 2011  |   Pubmed ID: 22168571
• Long-term Cultured Human Neural Stem Cells Undergo Spontaneous Transformation to Tumor-initiating Cells
  International Journal of Biological Sciences. 2011  |   Pubmed ID: 21814484
• Adoptive Transfer of Tumor Reactive B Cells Confers Host T-cell Immunity and Tumor Regression
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2011  |   Pubmed ID: 21690573
• Surgical Options for Localized and Advanced Gastrointestinal Stromal Tumors
  Journal of Surgical Oncology. Dec, 2011  |   Pubmed ID: 21381037
• Intratumoral Expression of IL-17 and Its Prognostic Role in Gastric Adenocarcinoma Patients
  International Journal of Biological Sciences. 2011  |   Pubmed ID: 21234303
• From the Guest Editors: Introduction to Local Therapies in the Treatment of Liver Cancer
  Cancer Journal (Sudbury, Mass.). Mar-Apr, 2010  |   Pubmed ID: 20404604
• Rate of Freeze Alters the Immunologic Response After Cryoablation of Breast Cancer
  Annals of Surgical Oncology. Apr, 2010  |   Pubmed ID: 20033323
• Intratumoral Delivery of Encapsulated IL-12, IL-18 and TNF-alpha in a Model of Metastatic Breast Cancer
  Breast Cancer Research and Treatment. Jul, 2010  |   Pubmed ID: 19802695
• Is There a Benefit to Sentinel Lymph Node Biopsy in Patients with T4 Melanoma?
  Cancer. Dec, 2009  |   Pubmed ID: 19827151
• Prognostic Significance of a Positive Nonsentinel Lymph Node in Cutaneous Melanoma
  Annals of Surgical Oncology. Nov, 2009  |   Pubmed ID: 19711133
• In Vivo Sensitized and in Vitro Activated B Cells Mediate Tumor Regression in Cancer Adoptive Immunotherapy
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2009  |   Pubmed ID: 19667089
• Radiotherapy Combined with Intratumoral Dendritic Cell Vaccination Enhances the Therapeutic Efficacy of Adoptive T-cell Transfer
  Journal of Immunotherapy (Hagerstown, Md. : 1997). Jul-Aug, 2009  |   Pubmed ID: 19483649
• Gemcitabine-based Combination Chemotherapy Followed by Radiation with Capecitabine As Adjuvant Therapy for Resected Pancreas Cancer
  International Journal of Radiation Oncology, Biology, Physics. Dec, 2009  |   Pubmed ID: 19409732
• SEA発現マウスB16メラノーマの所属リンパ節から生成され、第二に樹状細胞と活性化T細胞の抗腫瘍活性
  International Journal of Biological Sciences. 2009  |   Pubmed ID: 19173035
• Determinants of Breast Conservation Rates: Reasons for Mastectomy at a Comprehensive Cancer Center
  The Breast Journal. Jan-Feb, 2009  |   Pubmed ID: 19141132
• Residual Disease After Re-excision Lumpectomy for Close Margins
  Journal of Surgical Oncology. Feb, 2009  |   Pubmed ID: 19065638
• Dendritic Cells Pulsed with Keyhole Limpet Hemocyanin and Cryopreserved Maintain Anti-tumor Activity in a Murine Melanoma Model
  Clinical Immunology (Orlando, Fla.). Dec, 2008  |   Pubmed ID: 18845485
• Intratumoral Dendritic Cells and Chemoradiation for the Treatment of Murine Squamous Cell Carcinoma
  Journal of Immunotherapy (Hagerstown, Md. : 1997). Nov-Dec, 2008  |   Pubmed ID: 18832999
• Axillary Staging Prior to Neoadjuvant Chemotherapy for Breast Cancer: Predictors of Recurrence
  Annals of Surgical Oncology. Nov, 2008  |   Pubmed ID: 18784961
• Do Micromorphometric Features of Metastatic Deposits Within Sentinel Nodes Predict Nonsentinel Lymph Node Involvement in Melanoma?
  Annals of Surgical Oncology. Sep, 2008  |   Pubmed ID: 18626721
• In Vivo エフェクター T 細胞のプライミング腫瘍誘導免疫抑制 B7 H1/PD 1 軸と成長因子 β によって媒介されます。
  Cancer Research. Jul, 2008  |   Pubmed ID: 18593946
• Phase Ib Trial Assessing Autologous, Tumor-pulsed Dendritic Cells As a Vaccine Administered with or Without IL-2 in Patients with Metastatic Melanoma
  Journal of Immunotherapy (Hagerstown, Md. : 1997). Jul-Aug, 2008  |   Pubmed ID: 18528294
• Interleukin-21 Augments the Efficacy of T-cell Therapy by Eliciting Concurrent Cellular and Humoral Responses
  Cancer Research. Jun, 2008  |   Pubmed ID: 18519706
• Mechanisms Involved in Radiation Enhancement of Intratumoral Dendritic Cell Therapy
  Journal of Immunotherapy (Hagerstown, Md. : 1997). May, 2008  |   Pubmed ID: 18391761
• Adjuvant Effect of Anti-4-1BB MAb Administration in Adoptive T Cell Therapy of Cancer
  International Journal of Biological Sciences. 2007  |   Pubmed ID: 18071585
• Generation of a Tumor-specific Systemic Response After Intratumoral Injection of IL-12 and IL-18-loaded Polylactic Acid Microspheres
  Journal of Immunotherapy (Hagerstown, Md. : 1997). Nov-Dec, 2007  |   Pubmed ID: 18049332
• Synergistic Effect of Intratumoral IL-12 and TNF-alpha Microspheres: Systemic Anti-tumor Immunity is Mediated by Both CD8+ CTL and NK Cells
  Surgery. Nov, 2007  |   Pubmed ID: 17981196
• The Registry Case Finding Engine: an Automated Tool to Identify Cancer Cases from Unstructured, Free-text Pathology Reports and Clinical Notes
  Journal of the American College of Surgeons. Nov, 2007  |   Pubmed ID: 17964445
• Phase I Study of Oxaliplatin, Full-dose Gemcitabine, and Concurrent Radiation Therapy in Pancreatic Cancer
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2007  |   Pubmed ID: 17925553
• 相乗的 CCL19 と CXCL13 B 細胞急性リンパ性白血病 CD23 + CD5 + B 細胞と Cd8 陽性 T 細胞との相互作用を調節します。
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2007  |   Pubmed ID: 17709502
• Sentinel Lymph Node Biopsy for Breast Cancer: How Many Nodes Are Enough?
  Journal of Surgical Oncology. Dec, 2007  |   Pubmed ID: 17685432
• Inguinal Node Dissection for Melanoma in the Era of Sentinel Lymph Node Biopsy
  Surgery. Jun, 2007  |   Pubmed ID: 17560249
• Sentinel Lymph Node Biopsy Performed After Neoadjuvant Chemotherapy is Accurate in Patients with Documented Node-positive Breast Cancer at Presentation
  Annals of Surgical Oncology. Oct, 2007  |   Pubmed ID: 17514407
• 4-1BB Costimulation of Effector T Cells for Adoptive Immunotherapy of Cancer: Involvement of Bcl Gene Family Members
  Journal of Immunotherapy (Hagerstown, Md. : 1997). May-Jun, 2007  |   Pubmed ID: 17457215
• 放射線誘発アポトーシス全身及び肺局所のサイトカインの精緻化とともに DC プラス放射線療法を介した腎細胞腫瘍の回帰と関連付けられています。
  Clinical Immunology (Orlando, Fla.). Jun, 2007  |   Pubmed ID: 17449328
• What is a Sentinel Node? Re-evaluating the 10% Rule for Sentinel Lymph Node Biopsy in Melanoma
  Journal of Surgical Oncology. Jun, 2007  |   Pubmed ID: 17345610
• Improving Surgical Outcomes for Cancer in the United States
  Journal of Surgical Oncology. Feb, 2007  |   Pubmed ID: 17262738
• The Impact of Factors Beyond Breslow Depth on Predicting Sentinel Lymph Node Positivity in Melanoma
  Cancer. Jan, 2007  |   Pubmed ID: 17146784
• CXC Chemokine Ligand 13 and CC Chemokine Ligand 19 Cooperatively Render Resistance to Apoptosis in B Cell Lineage Acute and Chronic Lymphocytic Leukemia CD23+CD5+ B Cells
  Journal of Immunology (Baltimore, Md. : 1950). Nov, 2006  |   Pubmed ID: 17082584
• Changes in Surgical Management Resulting from Case Review at a Breast Cancer Multidisciplinary Tumor Board
  Cancer. Nov, 2006  |   Pubmed ID: 16998942
• Adoptive Immunotherapy of Breast Cancer with Lymph Node Cells Primed by Cryoablation of the Primary Tumor
  Cryobiology. Dec, 2006  |   Pubmed ID: 16973145
• Neoadjuvant Intratumoral Cytokine-loaded Microspheres Are Superior to Postoperative Autologous Cellular Vaccines in Generating Systemic Anti-tumor Immunity
  Journal of Surgical Oncology. Oct, 2006  |   Pubmed ID: 16967445
• Significance of Multiple Lymphatic Basin Drainage in Truncal Melanoma Patients Undergoing Sentinel Lymph Node Biopsy
  Annals of Surgical Oncology. Sep, 2006  |   Pubmed ID: 16952026
• Ex Vivo Culture with Interleukin (IL)-12 Improves CD8(+) T-cell Adoptive Immunotherapy for Murine Leukemia Independent of IL-18 or IFN-gamma but Requires Perforin
  Cancer Research. May, 2006  |   Pubmed ID: 16651448
• Does the Method of Biopsy Affect the Incidence of Sentinel Lymph Node Metastases?
  The Breast Journal. Jan-Feb, 2006  |   Pubmed ID: 16409587
• Clinicopathologic Features Associated with Having Four or More Metastatic Axillary Nodes in Breast Cancer Patients with a Positive Sentinel Lymph Node
  Annals of Surgical Oncology. Jan, 2006  |   Pubmed ID: 16378156
• Lymphatic Mapping and Sentinel Lymph Node Biopsy for Patients with Local Recurrence After Breast-conservation Therapy
  Annals of Surgical Oncology. Jan, 2006  |   Pubmed ID: 16372155
• Wide Excision Without Radiation for Desmoplastic Melanoma
  Cancer. Oct, 2005  |   Pubmed ID: 16080180
• Comprehensive Axillary Evaluation in Neoadjuvant Chemotherapy Patients with Ultrasonography and Sentinel Lymph Node Biopsy
  Annals of Surgical Oncology. Sep, 2005  |   Pubmed ID: 16079956
• Is Blue Dye Indicated for Sentinel Lymph Node Biopsy in Breast Cancer Patients with a Positive Lymphoscintigram?
  Annals of Surgical Oncology. Sep, 2005  |   Pubmed ID: 16079955
• Simultaneous Targeting of CD3 on T Cells and CD40 on B or Dendritic Cells Augments the Antitumor Reactivity of Tumor-primed Lymph Node Cells
  Journal of Immunology (Baltimore, Md. : 1950). Aug, 2005  |   Pubmed ID: 16034078
• Capecitabine and Radiation Therapy Preceded and Followed by Combination Chemotherapy in Advanced Pancreatic Cancer
  International Journal of Radiation Oncology, Biology, Physics. Dec, 2005  |   Pubmed ID: 15993549
• Predictors of Nonsentinel Lymph Node Positivity in Patients with a Positive Sentinel Node for Melanoma
  Journal of the American College of Surgeons. Jul, 2005  |   Pubmed ID: 15978442
• Immunologic Response to Cryoablation of Breast Cancer
  Breast Cancer Research and Treatment. Mar, 2005  |   Pubmed ID: 15770533
• Synergistic Effects of IL-12 and IL-18 in Skewing Tumor-reactive T-cell Responses Towards a Type 1 Pattern
  Cancer Research. Feb, 2005  |   Pubmed ID: 15705908
• Anti-CD137 Monoclonal Antibody Administration Augments the Antitumor Efficacy of Dendritic Cell-based Vaccines
  Cancer Research. Nov, 2004  |   Pubmed ID: 15548712
• An Academic Health Center Cost Analysis of Screening Mammography: Creating a Financially Viable Service
  Cancer. Sep, 2004  |   Pubmed ID: 15329914
• Mastectomy and Concomitant Sentinel Lymph Node Biopsy for Invasive Breast Cancer
  American Journal of Surgery. Jun, 2004  |   Pubmed ID: 15191855
• Efficacy of Sentinel Lymph Node Biopsy in Male Breast Cancer
  Journal of Surgical Oncology. May, 2004  |   Pubmed ID: 15112248
• Donor Cell Cycling, Trafficking, and Accumulation During Adoptive Immunotherapy for Murine Lung Metastases
  Cancer Research. Mar, 2004  |   Pubmed ID: 15026361
• Mitotic Rate and Younger Age Are Predictors of Sentinel Lymph Node Positivity: Lessons Learned from the Generation of a Probabilistic Model
  Annals of Surgical Oncology. Mar, 2004  |   Pubmed ID: 14993019
• Exaggerated Pigmented Granulomatous Reaction to the Artificial Joint Implant Mimics Metastatic Melanoma
  Diagnostic Cytopathology. Mar, 2004  |   Pubmed ID: 14986302
• Intratumoral IL-12 and TNF-alpha-loaded Microspheres Lead to Regression of Breast Cancer and Systemic Antitumor Immunity
  Annals of Surgical Oncology. Feb, 2004  |   Pubmed ID: 14761917
• Radiotherapy Potentiates the Therapeutic Efficacy of Intratumoral Dendritic Cell Administration
  Cancer Research. Dec, 2003  |   Pubmed ID: 14679011
• Clinicopathologic Features of Metastasis in Nonsentinel Lymph Nodes of Breast Carcinoma Patients
  Cancer. Dec, 2003  |   Pubmed ID: 14635063
• Sentinel Node Biopsy Prior to Neoadjuvant Chemotherapy
  American Journal of Surgery. Aug, 2003  |   Pubmed ID: 12885598
• Antitumor Reactivity of Anti-CD3/anti-CD28 Bead-activated Lymphoid Cells: Implications for Cell Therapy in a Murine Model
  Journal of Immunotherapy (Hagerstown, Md. : 1997). May-Jun, 2003  |   Pubmed ID: 12806276
• Polarization Effects of 4-1BB During CD28 Costimulation in Generating Tumor-reactive T Cells for Cancer Immunotherapy
  Cancer Research. May, 2003  |   Pubmed ID: 12750278
• Phase II Trial of Autologous Tumor Vaccination, Anti-CD3-activated Vaccine-primed Lymphocytes, and Interleukin-2 in Stage IV Renal Cell Cancer
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2003  |   Pubmed ID: 12610189
• Generation of Vaccine-primed Lymphocytes for the Treatment of Head and Neck Cancer
  Head & Neck. Mar, 2003  |   Pubmed ID: 12599287
• Comparison of Attenuation-corrected and Non-corrected FDG-PET Images for Axillary Nodal Staging in Newly Diagnosed Breast Cancer
  Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Mar, 2002  |   Pubmed ID: 14537139
• Applications of Gene Transfer to Cellular Immunotherapy
  Surgical Oncology Clinics of North America. Jul, 2002  |   Pubmed ID: 12487059
• Melanoma and Human Leukocyte Antigen Status: the Missing Link?
  Annals of Surgical Oncology. Oct, 2002  |   Pubmed ID: 12374654
• Hepatic Artery Chemotherapy for Colorectal Liver Metastases: Technical Considerations and Review of Clinical Trials
  Surgical Oncology. Nov, 2002  |   Pubmed ID: 12356508
• Therapeutic Effects of Tumor Reactive CD4+ Cells Generated from Tumor-primed Lymph Nodes Using Anti-CD3/anti-CD28 Monoclonal Antibodies
  Journal of Immunotherapy (Hagerstown, Md. : 1997). Jul-Aug, 2002  |   Pubmed ID: 12142553
• Mammographic Screening of TRAM Flap Breast Reconstructions for Detection of Nonpalpable Recurrent Cancer
  Radiology. Jul, 2002  |   Pubmed ID: 12091685
• Resection of Liver Tumors: Technical Aspects
  Surgical Oncology. May, 2002  |   Pubmed ID: 12020669
• A Phase I Trial of Tumor Lysate-pulsed Dendritic Cells in the Treatment of Advanced Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2002  |   Pubmed ID: 11948109