Alfred Fahr Department of Pharmaceutical Technology Friedrich-Schiller-University Jena Biography Publications Institution JoVE Articles Alfred Fahr has not added a biography. If you are Alfred Fahr and would like to personalize this page please email our Author Liaison for assistance. Publications Spontaneous Encapsulation and Concentration of Biological Macromolecules in Liposomes: an Intriguing Phenomenon and Its Relevance in Origins of Life Journal of Molecular Evolution. Dec, 2014 | Pubmed ID: 25416509 Electron Microscopy and Theoretical Modeling of Cochleates Langmuir : the ACS Journal of Surfaces and Colloids. Nov, 2014 | Pubmed ID: 25318049 Photodynamic Killing of Enterococcus Faecalis in Dentinal Tubules Using MTHPC Incorporated in Liposomes and Invasomes Clinical Oral Investigations. Jun, 2014 | Pubmed ID: 24950607 In Vivo Near-infrared Fluorescence Imaging of FAP-expressing Tumors with Activatable FAP-targeted, Single-chain Fv-immunoliposomes Journal of Controlled Release : Official Journal of the Controlled Release Society. Jul, 2014 | Pubmed ID: 24810115 Asymmetric Flow Field-flow Fractionation in the Field of Nanomedicine Analytical Chemistry. Jun, 2014 | Pubmed ID: 24802650 Study of PK Values and Effective Dielectric Constants of Ionizable Residues in Pentapeptides and in Staphylococcal Nuclease (SNase) Using a Mean-field Approach The Journal of Physical Chemistry. B. Apr, 2014 | Pubmed ID: 24708515 Influence of Massage and Occlusion on the Ex Vivo Skin Penetration of Rigid Liposomes and Invasomes European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V. Feb, 2014 | Pubmed ID: 24252713 [FeFe]-hydrogenase Models Assembled into Vesicular Structures Journal of Liposome Research. Mar, 2014 | Pubmed ID: 24006843 Novel Insights into Appropriate Encapsulation Methods for Bioactive Compounds into Polymers: a Study with Peptides and HDAC Inhibitors Macromolecular Bioscience. Jan, 2014 | Pubmed ID: 23966296 A Remarkable Self-organization Process As the Origin of Primitive Functional Cells Angewandte Chemie (International Ed. in English). Dec, 2013 | Pubmed ID: 24130192 Lipid Colloidal Carriers for Improvement of Anticancer Activity of Orally Delivered Quercetin: Formulation, Characterization and Establishing in Vitro-in Vivo Advantage Journal of Biomedical Nanotechnology. Jul, 2013 | Pubmed ID: 23909137 Comparative SAXS and DSC Study on Stratum Corneum Structural Organization in an Epidermal Cell Culture Model (ROC): Impact of Cultivation Time European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Dec, 2013 | Pubmed ID: 23770376 Non-invasive Depth Profile Imaging of the Stratum Corneum Using Confocal Raman Microscopy: First Insights into the Method European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Dec, 2013 | Pubmed ID: 23764946 Analysis of Immobilized Artificial Membrane Retention Factors for Both Neutral and Ionic Species Journal of Chromatography. A. Jul, 2013 | Pubmed ID: 23726245 Liposomal Encapsulation of a Near-infrared Fluorophore Enhances Fluorescence Quenching and Reliable Whole Body Optical Imaging Upon Activation in Vivo Small (Weinheim an Der Bergstrasse, Germany). Nov, 2013 | Pubmed ID: 23650267 Transfer of a Lipophilic Drug (temoporfin) Between Small Unilamellar Liposomes and Human Plasma Proteins: Influence of Membrane Composition on Vesicle Integrity and Release Characteristics Journal of Liposome Research. Jun, 2013 | Pubmed ID: 23590339 Pharmacokinetics of Temoporfin-loaded Liposome Formulations: Correlation of Liposome and Temoporfin Blood Concentration Journal of Controlled Release : Official Journal of the Controlled Release Society. Mar, 2013 | Pubmed ID: 23313962 Encapsulation of Ferritin, Ribosomes, and Ribo-peptidic Complexes Inside Liposomes: Insights into the Origin of Metabolism Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life. Oct, 2012 | Pubmed ID: 23080007 Degradation Kinetics of an Aspartyl-tripeptide-derived Diketopiperazine Under Forced Conditions Journal of Pharmaceutical Sciences. Nov, 2012 | Pubmed ID: 22899465 Analysis of Liposomes Using Asymmetrical Flow Field-flow Fractionation: Separation Conditions and Drug/lipid Recovery Journal of Separation Science. Aug, 2012 | Pubmed ID: 22865761 Elastic Vesicles for Transdermal Drug Delivery of Hydrophilic Drugs: a Comparison of Important Physicochemical Characteristics of Different Vesicle Types Journal of Biomedical Nanotechnology. Aug, 2012 | Pubmed ID: 22852471 Liposomes in Topical Photodynamic Therapy Expert Opinion on Drug Delivery. Aug, 2012 | Pubmed ID: 22731896 Selective Partitioning of Cholesterol and a Model Drug into Liposomes of Varying Size Chemistry and Physics of Lipids. Jul, 2012 | Pubmed ID: 22534024 Human Skin Permeation of Neutral Species and Ionic Species: Extended Linear Free-energy Relationship Analyses Journal of Pharmaceutical Sciences. Jun, 2012 | Pubmed ID: 22415339 Interfacial Concentrations of Chloride and Bromide in Zwitterionic Micelles with Opposite Dipoles: Experimental Determination by Chemical Trapping and a Theoretical Description Journal of Colloid and Interface Science. Apr, 2012 | Pubmed ID: 22305573 Wheat Germ Agglutinin Modified Liposomes for the Photodynamic Inactivation of Bacteria Photochemistry and Photobiology. May-Jun, 2012 | Pubmed ID: 21834868 Fast High-throughput Screening of Temoporfin-loaded Liposomal Formulations Prepared by Ethanol Injection Method Journal of Liposome Research. Mar, 2012 | Pubmed ID: 21682653 Lecithin-based Novel Cationic Nanocarriers (LeciPlex) I: Fabrication, Characterization and Evaluation Nanomedicine (London, England). Oct, 2011 | Pubmed ID: 22026377 Drug Delivery Strategies for Poorly Water-soluble Drugs: the Industrial Perspective Expert Opinion on Drug Delivery. Nov, 2011 | Pubmed ID: 21895540 Spontaneous Crowding of Ribosomes and Proteins Inside Vesicles: a Possible Mechanism for the Origin of Cell Metabolism Chembiochem : a European Journal of Chemical Biology. Oct, 2011 | Pubmed ID: 21830290 Liposomas Modificado Péptido Antimicrobianos Para Bacterias Habían Concentrado En Entrega De Temoporfina En Quimioterapia Antimicrobiana Fotodinámica Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. Oct, 2011 | Pubmed ID: 21773628 Modeling the Release Kinetics of Poorly Water-soluble Drug Molecules from Liposomal Nanocarriers Journal of Drug Delivery. 2011 | Pubmed ID: 21773045 [Non-viral Gene Transfer Medicinal Products. Therapy with Synthetic Vectors] Pharmazie in Unserer Zeit. May, 2011 | Pubmed ID: 21698610 Assessment of Fluidity of Different Invasomes by Electron Spin Resonance and Differential Scanning Calorimetry International Journal of Pharmaceutics. Jun, 2011 | Pubmed ID: 21527323 Lecithin-based Novel Cationic Nanocarriers (Leciplex) II: Improving Therapeutic Efficacy of Quercetin on Oral Administration Molecular Pharmaceutics. Jun, 2011 | Pubmed ID: 21480639 The Physical State of Lipid Nanoparticles Influences Their Effect on in Vitro Cell Viability European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V. Sep, 2011 | Pubmed ID: 21458564 Análisis De Relación Lineal De Energía Libre De Factores De Retención En Cerasome Cromatografía Electrocinética Para Predecir La Impregnación De La Piel Del Fármaco Journal of Pharmaceutical Sciences. Aug, 2011 | Pubmed ID: 21455982 Penetración Y Deposición De Carboxyfluorescein Y Temoporfina De Sistemas Vesiculares Diferentes Lípidos De La Piel: Estudio In Vitro Con La Aplicación De Dosis Finito E Infinito International Journal of Pharmaceutics. Apr, 2011 | Pubmed ID: 21316430 Lipophilicity and Its Relationship with Passive Drug Permeation Pharmaceutical Research. May, 2011 | Pubmed ID: 21052797 Cellular Uptake and Degradation Behaviour of Biodegradable Poly(ethylene Glycol-graft-methyl Methacrylate) Nanoparticles Crosslinked with Dimethacryloyl Hydroxylamine International Journal of Pharmaceutics. Jan, 2011 | Pubmed ID: 20969936 Transfer Mechanism of Temoporfin Between Liposomal Membranes Journal of Controlled Release : Official Journal of the Controlled Release Society. Mar, 2011 | Pubmed ID: 20888878 Polymersomes Containing Iron Sulfide (FeS) As Primordial Cell Model : for the Investigation of Energy Providing Redox Reactions Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life. Apr, 2011 | Pubmed ID: 20697814 Entrega De ácido Ferúlico De Diferentes Sistemas Vesiculares De La Piel Journal of Biomedical Nanotechnology. Oct, 2010 | Pubmed ID: 21329050 DHPC Strongly Affects the Structure and Oligomerization Propensity of Alzheimer's Aβ(1-40) Peptide Journal of Molecular Biology. Nov, 2010 | Pubmed ID: 20851128 Spontaneous Protein Crowding in Liposomes: a New Vista for the Origin of Cellular Metabolism Chembiochem : a European Journal of Chemical Biology. Sep, 2010 | Pubmed ID: 20806308 Efficacy of Temoporfin-loaded Invasomes in the Photodynamic Therapy in Human Epidermoid and Colorectal Tumour Cell Lines Journal of Photochemistry and Photobiology. B, Biology. Dec, 2010 | Pubmed ID: 20797872 Kinetics of Aspartic Acid Isomerization and Enantiomerization in Model Aspartyl Tripeptides Under Forced Conditions Journal of Pharmaceutical Sciences. Oct, 2010 | Pubmed ID: 20737625 Temoporfin-loaded Liposomes: Physicochemical Characterization European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Jul, 2010 | Pubmed ID: 20412853 Flow Cytometry As a New Approach to Investigate Drug Transfer Between Lipid Particles Molecular Pharmaceutics. Apr, 2010 | Pubmed ID: 20063898 Utilization of Liposomes for Studying Drug Transfer and Uptake Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20013385 Micro-structured Smart Hydrogels with Enhanced Protein Loading and Release Efficiency Acta Biomaterialia. Apr, 2010 | Pubmed ID: 19913647 Surface Charged Temoporfin-loaded Flexible Vesicles: in Vitro Skin Penetration Studies and Stability International Journal of Pharmaceutics. Jan, 2010 | Pubmed ID: 19819321 Stability Evaluation of Temoporfin-loaded Liposomal Gels for Topical Application Journal of Liposome Research. Mar, 2010 | Pubmed ID: 19558347 Preservation of Liquid Drug Preparations for Oral Administration Journal of Pharmaceutical Sciences. Jan, 2010 | Pubmed ID: 19499567 Supercooled Smectic Nanoparticles: Influence of the Matrix Composition and in Vitro Cytotoxicity European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Oct, 2009 | Pubmed ID: 19664705 Development of Liposomes Containing Ethanol for Skin Delivery of Temoporfin: Characterization and in Vitro Penetration Studies Colloids and Surfaces. B, Biointerfaces. Nov, 2009 | Pubmed ID: 19651496 Temoporfin-loaded Liposomal Gels: Viscoelastic Properties and in Vitro Skin Penetration International Journal of Pharmaceutics. May, 2009 | Pubmed ID: 19429291 Development of Different Temoporfin-loaded Invasomes-novel Nanocarriers of Temoporfin: Characterization, Stability and in Vitro Skin Penetration Studies Colloids and Surfaces. B, Biointerfaces. May, 2009 | Pubmed ID: 19188048 Efficiency of Cytoplasmic Delivery by Non-cationic Liposomes to Cells in Vitro: a Confocal Laser Scanning Microscopy Study Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB). Jun, 2009 | Pubmed ID: 18590977 Lipophilicity Measurement of Drugs by Reversed Phase HPLC over Wide PH Range Using an Alkaline-resistant Silica-based Stationary Phase, XBridge Shield RP(18) Chemical & Pharmaceutical Bulletin. Oct, 2008 | Pubmed ID: 18827381 Fluorescent Liposomes As Contrast Agents for in Vivo Optical Imaging of Edemas in Mice Small (Weinheim an Der Bergstrasse, Germany). Aug, 2008 | Pubmed ID: 18666163 Topical Application of Temoporfin-loaded Invasomes for Photodynamic Therapy of Subcutaneously Implanted Tumours in Mice: a Pilot Study Journal of Photochemistry and Photobiology. B, Biology. Apr, 2008 | Pubmed ID: 18316200 Permeability Changes in Response to NONOate and NONOate Prodrug Derived Nitric Oxide in a Blood-brain Barrier Model Formed by Primary Porcine Endothelial Cells Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. May, 2008 | Pubmed ID: 18284923 Temoporfin-loaded Invasomes: Development, Characterization and in Vitro Skin Penetration Studies Journal of Controlled Release : Official Journal of the Controlled Release Society. Apr, 2008 | Pubmed ID: 18281119 A Novel Gene Delivery System for Stable Transfection of Thiopurine-S-methyltransferase Gene in Versatile Cell Types European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V. May, 2008 | Pubmed ID: 17988843 Interaction of Lipid Nanoparticles with Human Epidermis and an Organotypic Cell Culture Model International Journal of Pharmaceutics. Apr, 2008 | Pubmed ID: 17920216 Using a Modified Shepards Method for Optimization of a Nanoparticulate Cyclosporine a Formulation Prepared by a Static Mixer Technique Journal of Pharmaceutical Sciences. Feb, 2008 | Pubmed ID: 17853428 Drug Delivery Strategies for Poorly Water-soluble Drugs Expert Opinion on Drug Delivery. Jul, 2007 | Pubmed ID: 17683253 Physicochemical Characterization of Solid Dispersions of Three Antiepileptic Drugs Prepared by Solvent Evaporation Method The Journal of Pharmacy and Pharmacology. May, 2007 | Pubmed ID: 17524229 In Vitro Characterization of Binding and Stability of Single-chain Fv Ni-NTA-liposomes Journal of Drug Targeting. Sep, 2006 | Pubmed ID: 17050123 Lipophilic Drug Transfer Between Liposomal and Biological Membranes: What Does It Mean for Parenteral and Oral Drug Delivery? Journal of Liposome Research. 2006 | Pubmed ID: 16952882 Adaptive Neuro-fuzzy Modeling of Poorly Soluble Drug Formulations Pharmaceutical Research. Jun, 2006 | Pubmed ID: 16715373 Electrostatic Model for Mixed Cationic-zwitterionic Lipid Bilayers Langmuir : the ACS Journal of Surfaces and Colloids. May, 2006 | Pubmed ID: 16700604 Octaarginine De Stearylated Y Partículas De Tipo Virus Artificiales Para Transfección De SiRNA En Neuronas De Rata Primario RNA (New York, N.Y.). Jul, 2006 | Pubmed ID: 16699166 Generation of Immunoliposomes Using Recombinant Single-chain Fv Fragments Bound to Ni-NTA-liposomes Journal of Drug Targeting. Aug, 2005 | Pubmed ID: 16308208 Transfer of Lipophilic Drugs Between Liposomal Membranes and Biological Interfaces: Consequences for Drug Delivery European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Nov, 2005 | Pubmed ID: 16112849 Novel Lipid Nanotubes in Dispersions of DMPC Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Aug, 2004 | Pubmed ID: 15446752 Efficient Gene Delivery with Serum into Human Cancer Cells Using Targeted Anionic Liposomes Journal of Drug Targeting. Jan, 2004 | Pubmed ID: 15203907 Encapsulation of Gadobutrol in AVE-based Liposomal Carriers for MR Detectability Magnetic Resonance Imaging. May, 2004 | Pubmed ID: 15120167 Sustained-release Injectables Formed in Situ and Their Potential Use for Veterinary Products Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2002 | Pubmed ID: 12480306 Interactions of Cyclosporines with Lipid Membranes As Studied by Solid-state Nuclear Magnetic Resonance Spectroscopy and High-sensitivity Titration Calorimetry Journal of Pharmaceutical Sciences. Mar, 2002 | Pubmed ID: 11920770 Fluorescencia de extinción de un fluoróforo encapsulada en liposomas en infrarrojo cercano como herramienta para Felista L. Tansi*1, Ronny Rüger*2, Markus Rabenhold2, Frank Steiniger3, Alfred Fahr2, Ingrid Hilger1 1Experimental Radiology, Institute of Diagnostic and Interventional Radiology I, Jena University Hospital, 2Department of Pharmaceutical Technology, Friedrich-Schiller-University Jena, 3Center for Electron Microscopy, Jena University Hospital Bioengineering
Fluorescencia de extinción de un fluoróforo encapsulada en liposomas en infrarrojo cercano como herramienta para Felista L. Tansi*1, Ronny Rüger*2, Markus Rabenhold2, Frank Steiniger3, Alfred Fahr2, Ingrid Hilger1 1Experimental Radiology, Institute of Diagnostic and Interventional Radiology I, Jena University Hospital, 2Department of Pharmaceutical Technology, Friedrich-Schiller-University Jena, 3Center for Electron Microscopy, Jena University Hospital Bioengineering