Andrew E. Gelman Division of Cardiothoracic Surgery Washington University in St. Louis Biography Publications Institution JoVE Articles Andrew E. Gelman has not added a biography. If you are Andrew E. Gelman and would like to personalize this page please email our Author Liaison for assistance. Publications Alveolar Macrophage-CD8 T Cell Interactions After Acute Lung Allograft Dysfunction: Insights from Single-cell RNA Sequencing The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Mar, 2024 | Pubmed ID: 38490571 Eosinophils Restrain Humoral Alloimmunity After Lung Transplantation JCI Insight. Feb, 2024 | Pubmed ID: 38329123 A Pilot Randomized Controlled Trial of De Novo Belatacept-based Immunosuppression After Lung Transplantation Transplantation. Oct, 2023 | Pubmed ID: 37899481 Resolvin D1 Prevents Injurious Neutrophil Swarming in Transplanted Lungs Proceedings of the National Academy of Sciences of the United States of America. Aug, 2023 | Pubmed ID: 37487095 Increased Clonal Hematopoiesis Involving DNA Damage Response Genes in Patients Undergoing Lung Transplantation JCI Insight. Apr, 2023 | Pubmed ID: 36853803 Avoid Being Trapped by Your Liver: Ischemia-reperfusion Injury in Liver Transplant Triggers S1P-mediated NETosis The Journal of Clinical Investigation. Feb, 2023 | Pubmed ID: 36719374 Reprogramming Alveolar Macrophage Responses to TGF-β Reveals CCR2+ Monocyte Activity That Promotes Bronchiolitis Obliterans Syndrome The Journal of Clinical Investigation. Oct, 2022 | Pubmed ID: 36189800 The Role of Neutrophil Extracellular Traps in Acute Lung Injury Frontiers in Immunology. 2022 | Pubmed ID: 35967320 Loss of Stromal Cell Thy-1 Plays a Critical Role in Lipopolysaccharide Induced Chronic Lung Allograft Dysfunction The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Aug, 2022 | Pubmed ID: 35691796 Role of Tertiary Lymphoid Organs in the Regulation of Immune Responses in the Periphery Cellular and Molecular Life Sciences : CMLS. Jun, 2022 | Pubmed ID: 35689679 Ischemia Reperfusion Injury Facilitates Lung Allograft Acceptance Through IL-33-mediated Activation of Donor-derived IL-5 Producing Group 2 Innate Lymphoid Cells American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Aug, 2022 | Pubmed ID: 35510760 Short Telomeres in Lung Transplantation: Known Unknowns The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. May, 2022 | Pubmed ID: 35351386 Targeting Fatty Acid β-oxidation Impairs Monocyte Differentiation and Prolongs Heart Allograft Survival JCI Insight. 04, 2022 | Pubmed ID: 35239515 Necroptosis Triggers Spatially Restricted Neutrophil-mediated Vascular Damage During Lung Ischemia Reperfusion Injury Proceedings of the National Academy of Sciences of the United States of America. Mar, 2022 | Pubmed ID: 35238643 Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report American Journal of Respiratory Cell and Molecular Biology. 02, 2022 | Pubmed ID: 35103557 Solving the Conundrum of Eosinophils in Alloimmunity Transplantation. Aug, 2022 | Pubmed ID: 34966103 Increased Complement Activation is a Distinctive Feature of Severe SARS-CoV-2 Infection Science Immunology. 05, 2021 | Pubmed ID: 34446527 Selective Imaging of Lung Macrophages Using [C]PBR28-Based Positron Emission Tomography Molecular Imaging and Biology. 12, 2021 | Pubmed ID: 34137002 Innate Immunity in Lung Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. 07, 2021 | Pubmed ID: 34020867 Increased Complement Activation is a Distinctive Feature of Severe SARS-CoV-2 Infection BioRxiv : the Preprint Server for Biology. Feb, 2021 | Pubmed ID: 33655244 COVID-19 Vaccination in Our Transplant Recipients: The Time is Now The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. 03, 2021 | Pubmed ID: 33487534 Circulating Mitochondrial DNA is an Early Indicator of Severe Illness and Mortality from COVID-19 JCI Insight. 02, 2021 | Pubmed ID: 33444289 Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity Cell Metabolism. 02, 2021 | Pubmed ID: 33278339 Pericardial Mitochondrial DNA Levels Are Associated With Atrial Fibrillation After Cardiac Surgery The Annals of Thoracic Surgery. 05, 2021 | Pubmed ID: 32946846 Lymphatic Drainage from Bronchus-associated Lymphoid Tissue in Tolerant Lung Allografts Promotes Peripheral Tolerance The Journal of Clinical Investigation. 12, 2020 | Pubmed ID: 33196461 Galuminox: Preclinical Validation of a Novel PET Tracer for Non-invasive Imaging of Oxidative Stress in Vivo Redox Biology. 10, 2020 | Pubmed ID: 33039825 Local Complement Activation is Associated with Primary Graft Dysfunction After Lung Transplantation JCI Insight. 09, 2020 | Pubmed ID: 32750037 Recent Advances into the Role of Pattern Recognition Receptors in Transplantation Cellular Immunology. 05, 2020 | Pubmed ID: 32183988 Perfect Timing: Circadian Rhythms, Sleep, and Immunity - an NIH Workshop Summary JCI Insight. 01, 2020 | Pubmed ID: 31941836 Pseudomonas Aeruginosa and Acute Rejection Independently Increase the Risk of Donor-specific Antibodies After Lung Transplantation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 04, 2020 | Pubmed ID: 31677358 Deciphering the Role of Eosinophils in Solid Organ Transplantation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Apr, 2020 | Pubmed ID: 31647606 Vendor-specific Microbiome Controls Both Acute and Chronic Murine Lung Allograft Rejection by Altering CD4 Foxp3 Regulatory T Cell Levels American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Oct, 2019 | Pubmed ID: 31278849 An Obligatory Role for Club Cells in Preventing Obliterative Bronchiolitis in Lung Transplants JCI Insight. 04, 2019 | Pubmed ID: 30990794 Mitochondrial Damage-associated Molecular Patterns Released by Lung Transplants Are Associated with Primary Graft Dysfunction American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 05, 2019 | Pubmed ID: 30582269 Bronchus-associated Lymphoid Tissue-resident Foxp3+ T Lymphocytes Prevent Antibody-mediated Lung Rejection The Journal of Clinical Investigation. 02, 2019 | Pubmed ID: 30561386 Neutrophil Extracellular Trap Fragments Stimulate Innate Immune Responses That Prevent Lung Transplant Tolerance American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 04, 2019 | Pubmed ID: 30378766 Spleen-derived Classical Monocytes Mediate Lung Ischemia-reperfusion Injury Through IL-1β The Journal of Clinical Investigation. Jul, 2018 | Pubmed ID: 29781811 Diagnosis, Pathophysiology and Experimental Models of Chronic Lung Allograft Rejection Transplantation. 09, 2018 | Pubmed ID: 29683998 Visualization of Monocytic Cells in Regressing Atherosclerotic Plaques by Intravital 2-Photon and Positron Emission Tomography-Based Imaging-Brief Report Arteriosclerosis, Thrombosis, and Vascular Biology. 05, 2018 | Pubmed ID: 29567678 Naive CD4 T Cells Carrying a TLR2 Agonist Overcome TGF-β-Mediated Tumor Immune Evasion Journal of Immunology (Baltimore, Md. : 1950). 01, 2018 | Pubmed ID: 29212908 Eosinophils Promote Inducible NOS-mediated Lung Allograft Acceptance JCI Insight. Dec, 2017 | Pubmed ID: 29263310 Mechanisms of Graft Rejection and Immune Regulation After Lung Transplant Annals of the American Thoracic Society. Sep, 2017 | Pubmed ID: 28945475 Endotracheal Tube-induced Sore Throat Pain and Inflammation is Coupled to the Release of Mitochondrial DNA Molecular Pain. 2017 | Pubmed ID: 28929859 Report of the ISHLT Working Group on Primary Lung Graft Dysfunction Part III: Mechanisms: A 2016 Consensus Group Statement of the International Society for Heart and Lung Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. 10, 2017 | Pubmed ID: 28818404 Zbtb7a Induction in Alveolar Macrophages is Implicated in Anti-HLA-mediated Lung Allograft Rejection Science Translational Medicine. Jul, 2017 | Pubmed ID: 28701473 Models of Lung Transplant Research: a Consensus Statement from the National Heart, Lung, and Blood Institute Workshop JCI Insight. May, 2017 | Pubmed ID: 28469087 CD36 Deficiency Impairs the Small Intestinal Barrier and Induces Subclinical Inflammation in Mice Cellular and Molecular Gastroenterology and Hepatology. Jan, 2017 | Pubmed ID: 28066800 The Role of Neutrophils in Transplanted Organs American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 02, 2017 | Pubmed ID: 27344051 Deficiency of the Adaptor Protein SLy1 Results in a Natural Killer Cell Ribosomopathy Affecting Tumor Clearance Oncoimmunology. 2016 | Pubmed ID: 28123874 Selective Targeting of IL-2 to NKG2D Bearing Cells for Improved Immunotherapy Nature Communications. Sep, 2016 | Pubmed ID: 27650575 Heart-resident CCR2 Macrophages Promote Neutrophil Extravasation Through TLR9/MyD88/CXCL5 Signaling JCI Insight. Aug, 2016 | Pubmed ID: 27536731 Noninvasive Imaging of CCR2 Cells in Ischemia-Reperfusion Injury After Lung Transplantation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 10, 2016 | Pubmed ID: 27273836 The Role of Lymphoid Neogenesis in Allografts American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Apr, 2016 | Pubmed ID: 26614734 De Novo-developed Antibodies to Donor MHC Antigens Lead to Dysregulation of MicroRNAs and Induction of MHC Class II Journal of Immunology (Baltimore, Md. : 1950). Jun, 2015 | Pubmed ID: 25941328 DAP12 Expression in Lung Macrophages Mediates Ischemia/reperfusion Injury by Promoting Neutrophil Extravasation Journal of Immunology (Baltimore, Md. : 1950). Apr, 2015 | Pubmed ID: 25762783 Human Recombinant Apyrase Therapy Protects Against Canine Pulmonary Ischemia-reperfusion Injury The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Feb, 2015 | Pubmed ID: 25455749 Imaging Mouse Lung Allograft Rejection with (1)H MRI Magnetic Resonance in Medicine. May, 2015 | Pubmed ID: 24954886 Lung Transplant Immunosuppression - Time for a New Approach? Expert Review of Clinical Immunology. Nov, 2014 | Pubmed ID: 25220652 The Role of Neutrophil Myeloperoxidase in Models of Lung Tumor Development Cancers. May, 2014 | Pubmed ID: 24821130 Central Memory CD8+ T Lymphocytes Mediate Lung Allograft Acceptance The Journal of Clinical Investigation. Mar, 2014 | Pubmed ID: 24569377 Hyaluronan Contributes to Bronchiolitis Obliterans Syndrome and Stimulates Lung Allograft Rejection Through Activation of Innate Immunity American Journal of Respiratory and Critical Care Medicine. Mar, 2014 | Pubmed ID: 24471427 Increased T Cell Glucose Uptake Reflects Acute Rejection in Lung Grafts American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Oct, 2013 | Pubmed ID: 23927673 Surgical Technique for Lung Retransplantation in the Mouse Journal of Thoracic Disease. Jun, 2013 | Pubmed ID: 23825768 Cutting Edge: Pseudomonas Aeruginosa Abolishes Established Lung Transplant Tolerance by Stimulating B7 Expression on Neutrophils Journal of Immunology (Baltimore, Md. : 1950). Nov, 2012 | Pubmed ID: 23018463 Complement Activation is Not Required for Obliterative Airway Disease Induced by Antibodies to Major Histocompatibility Complex Class I: Implications for Chronic Lung Rejection The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Nov, 2012 | Pubmed ID: 22980951 Five-year Update on the Mouse Model of Orthotopic Lung Transplantation: Scientific Uses, Tricks of the Trade, and Tips for Success Journal of Thoracic Disease. Jun, 2012 | Pubmed ID: 22754663 Strain-specific Variation in Murine Natural Killer Gene Complex Contributes to Differences in Immunosurveillance for Urethane-induced Lung Cancer Cancer Research. Sep, 2012 | Pubmed ID: 22751136 Intravital 2-photon Imaging of Leukocyte Trafficking in Beating Heart The Journal of Clinical Investigation. Jul, 2012 | Pubmed ID: 22706307 Lung Transplant Acceptance is Facilitated by Early Events in the Graft and is Associated with Lymphoid Neogenesis Mucosal Immunology. Sep, 2012 | Pubmed ID: 22549742 Quantitative Monitoring of Mouse Lung Tumors by Magnetic Resonance Imaging Nature Protocols. Jan, 2012 | Pubmed ID: 22222788 HIF-1α Signaling by Airway Epithelial Cell K-α1-tubulin: Role in Fibrosis and Chronic Rejection of Human Lung Allografts Cellular Immunology. 2012 | Pubmed ID: 22192476 Neutrophils Are Required for 3-methylcholanthrene-initiated, Butylated Hydroxytoluene-promoted Lung Carcinogenesis Molecular Carcinogenesis. Dec, 2012 | Pubmed ID: 22006501 Emergency Granulopoiesis Promotes Neutrophil-dendritic Cell Encounters That Prevent Mouse Lung Allograft Acceptance Blood. Dec, 2011 | Pubmed ID: 21972291 Polarized Alloantigen Presentation by Airway Epithelial Cells Contributes to Direct CD8+ T Cell Activation in the Airway American Journal of Respiratory Cell and Molecular Biology. Jun, 2011 | Pubmed ID: 21653906 Maintenance of IKKβ Activity is Necessary to Protect Lung Grafts from Acute Injury Transplantation. Mar, 2011 | Pubmed ID: 21293322 Bcl3 Prevents Acute Inflammatory Lung Injury in Mice by Restraining Emergency Granulopoiesis The Journal of Clinical Investigation. Jan, 2011 | Pubmed ID: 21157041 Current Status of Immunotherapy for the Treatment of Lung Cancer Journal of Thoracic Disease. Dec, 2010 | Pubmed ID: 22263052 Cutting Edge: MHC Class II Expression by Pulmonary Nonhematopoietic Cells Plays a Critical Role in Controlling Local Inflammatory Responses Journal of Immunology (Baltimore, Md. : 1950). Oct, 2010 | Pubmed ID: 20810992 Two-photon Microscopy in Pulmonary Research Seminars in Immunopathology. Sep, 2010 | Pubmed ID: 20589501 Strain-specific Susceptibility for Pulmonary Metastasis of Sarcoma 180 Cells in Inbred Mice Cancer Research. Jun, 2010 | Pubmed ID: 20501835 Orthotopic Vascularized Right Lung Transplantation in the Mouse The Journal of Thoracic and Cardiovascular Surgery. Jun, 2010 | Pubmed ID: 20219214 Apyrase Treatment Prevents Ischemia-reperfusion Injury in Rat Lung Isografts The Journal of Thoracic and Cardiovascular Surgery. Sep, 2009 | Pubmed ID: 19698866 Orthotopic Mouse Lung Transplantation As Experimental Methodology to Study Transplant and Tumor Biology Nature Protocols. 2009 | Pubmed ID: 19131960 Pathogenesis, Management, and Consequences of Primary Graft Dysfunction Seminars in Thoracic and Cardiovascular Surgery. 2008 | Pubmed ID: 18707651 The Feasibility of Diaphragmatic Transplantation As Potential Therapy for Treatment of Respiratory Failure Associated with Duchenne Muscular Dystrophy: Acute Canine Model The Journal of Thoracic and Cardiovascular Surgery. Jun, 2008 | Pubmed ID: 18544399 CD4+ T Lymphocytes Are Not Necessary for the Acute Rejection of Vascularized Mouse Lung Transplants Journal of Immunology (Baltimore, Md. : 1950). Apr, 2008 | Pubmed ID: 18354199 Maintenance of Airway Epithelium in Acutely Rejected Orthotopic Vascularized Mouse Lung Transplants American Journal of Respiratory Cell and Molecular Biology. Dec, 2007 | Pubmed ID: 17717320 Murine Vascular Endothelium Activates and Induces the Generation of Allogeneic CD4+25+Foxp3+ Regulatory T Cells Journal of Immunology (Baltimore, Md. : 1950). Nov, 2005 | Pubmed ID: 16272276 Intravital Two-Photon Microscopy of the Transplanted Mouse Lung Yun Zhu Bai1, Yuriko Terada1, Katsutaka Mineura1, Yuhei Yokoyama1, Ruben G. Nava1, Alexander S. Krupnick2, Andrew E. Gelman1, Mark J. Miller3, Daniel Kreisel1, Wenjun Li1 1Division of Cardiothoracic Surgery, Washington University in St. Louis, 2Division of Thoracic Surgery, University of Maryland, 3Division of Infectious Diseases, Washington University in St. Louis JoVE 66566 Medicine Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs Wenjun Li1, Hailey M. Shepherd1, Alexander S. Krupnick2, Andrew E. Gelman1,3, Kory J. Lavine4, Daniel Kreisel1,3 1Department of Surgery, Washington University School of Medicine, 2Department of Surgery, The University of Maryland, 3Department of Pathology & Immunology, Washington University School of Medicine, 4Department of Medicine, Washington University School of Medicine JoVE 64089 Immunology and Infection
Intravital Two-Photon Microscopy of the Transplanted Mouse Lung Yun Zhu Bai1, Yuriko Terada1, Katsutaka Mineura1, Yuhei Yokoyama1, Ruben G. Nava1, Alexander S. Krupnick2, Andrew E. Gelman1, Mark J. Miller3, Daniel Kreisel1, Wenjun Li1 1Division of Cardiothoracic Surgery, Washington University in St. Louis, 2Division of Thoracic Surgery, University of Maryland, 3Division of Infectious Diseases, Washington University in St. Louis JoVE 66566 Medicine
Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs Wenjun Li1, Hailey M. Shepherd1, Alexander S. Krupnick2, Andrew E. Gelman1,3, Kory J. Lavine4, Daniel Kreisel1,3 1Department of Surgery, Washington University School of Medicine, 2Department of Surgery, The University of Maryland, 3Department of Pathology & Immunology, Washington University School of Medicine, 4Department of Medicine, Washington University School of Medicine JoVE 64089 Immunology and Infection
