Andrew M. Lowy

Publications

• Laparoscopic Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: a Prospective Clinical Trial and Comparative Analysis
  Surgical Endoscopy. Dec, 2022  |   Pubmed ID: 36477643
• ASO Visual Abstract: Is Routine Omentectomy a Necessary Component of Cytoreductive Surgery and HIPEC?
  Annals of Surgical Oncology. Nov, 2022  |   Pubmed ID: 36369408
• Is Routine Omentectomy a Necessary Component of Cytoreductive Surgery and HIPEC?
  Annals of Surgical Oncology. Oct, 2022  |   Pubmed ID: 36305990
• Collagenolysis-dependent DDR1 Signalling Dictates Pancreatic Cancer Outcome
  Nature. Oct, 2022  |   Pubmed ID: 36198801
• Alvimopan for Enhanced Gastrointestinal Recovery After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Randomized Controlled Trial
  Journal of the American College of Surgeons. Nov, 2022  |   Pubmed ID: 36102565
• An Ex Vivo Organotypic Culture Platform for Functional Interrogation of Human Appendiceal Cancer Reveals a Prominent and Heterogenous Immunological Landscape
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2022  |   Pubmed ID: 36067351
• Early-stage Multi-cancer Detection Using an Extracellular Vesicle Protein-based Blood Test
  Communications Medicine. 2022  |   Pubmed ID: 35603292
• The MST1R/RON Tyrosine Kinase in Cancer: Oncogenic Functions and Therapeutic Strategies
  Cancers. Apr, 2022  |   Pubmed ID: 35454943
• Fluorescent Anti-MUC5AC Brightly Targets Pancreatic Cancer in a Patient-derived Orthotopic Xenograft
  In Vivo (Athens, Greece). 2022  |   Pubmed ID: 34972700
• Establishment of Patient-Derived Pancreatic Cancer Organoids from Endoscopic Ultrasound-Guided Fine-Needle Aspiration Biopsies
  Gut and Liver. Jul, 2022  |   Pubmed ID: 34916338
• Author Correction: Targeting LIF-mediated Paracrine Interaction for Pancreatic Cancer Therapy and Monitoring
  Nature. Dec, 2021  |   Pubmed ID: 34848876
• Using Organotypic Tissue Slices to Investigate the Microenvironment of Pancreatic Cancer: Pharmacotyping and Beyond
  Cancers. Oct, 2021  |   Pubmed ID: 34638476
• Randomized Phase II Study of PARP Inhibitor ABT-888 (Veliparib) with Modified FOLFIRI Versus FOLFIRI As Second-line Treatment of Metastatic Pancreatic Cancer: SWOG S1513
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2021  |   Pubmed ID: 34580114
• Tri-modal Management of Primary Small Cell Carcinoma of the Pancreas (SCCP): a Rare Neuroendocrine Carcinoma (NEC)
  BMC Gastroenterology. Sep, 2021  |   Pubmed ID: 34479480
• Ki67 Does Not Predict Recurrence for Low-grade Appendiceal Mucinous Neoplasms with Peritoneal Dissemination After Cytoreductive Surgery and HIPEC
  Human Pathology. Jul, 2021  |   Pubmed ID: 33905776
• Tumor-penetrating Therapy for β5 Integrin-rich Pancreas Cancer
  Nature Communications. Mar, 2021  |   Pubmed ID: 33750829
• Cancer Cells Escape Autophagy Inhibition Via NRF2-induced Macropinocytosis
  Cancer Cell. May, 2021  |   Pubmed ID: 33740421
• Clinical Data Prediction Model to Identify Patients With Early-Stage Pancreatic Cancer
  JCO Clinical Cancer Informatics. Mar, 2021  |   Pubmed ID: 33739856
• Predictors and Significance of Histologic Response to Neoadjuvant Therapy for Gastric Cancer
  Journal of Surgical Oncology. May, 2021  |   Pubmed ID: 33735448
• Macropinocytosis in Cancer-Associated Fibroblasts Is Dependent on CaMKK2/ARHGEF2 Signaling and Functions to Support Tumor and Stromal Cell Fitness
  Cancer Discovery. Jul, 2021  |   Pubmed ID: 33653692
• Phase I Trial of Stereotactic Body Radiation Therapy Dose Escalation in Pancreatic Cancer
  International Journal of Radiation Oncology, Biology, Physics. Jul, 2021  |   Pubmed ID: 33571625
• Efficacy of Perioperative Chemotherapy for Resectable Pancreatic Adenocarcinoma: A Phase 2 Randomized Clinical Trial
  JAMA Oncology. Mar, 2021  |   Pubmed ID: 33475684
• A MET Targeting Antibody-Drug Conjugate Overcomes Gemcitabine Resistance in Pancreatic Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2021  |   Pubmed ID: 33451980
• A Multi-institutional Study of Peritoneal Recurrence Following Resection of Low-grade Appendiceal Mucinous Neoplasms
  Annals of Surgical Oncology. Aug, 2021  |   Pubmed ID: 33415564
• Preoperative Bevacizumab Does Not Increase Complications Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
  PloS One. 2020  |   Pubmed ID: 33270763
• Prognostic Utility of Pre- and Postoperative Circulating Tumor DNA Liquid Biopsies in Patients with Peritoneal Metastases
  Annals of Surgical Oncology. Sep, 2020  |   Pubmed ID: 32767050
• Surgical Outcome Results From SWOG S1505: A Randomized Clinical Trial of MFOLFIRINOX Versus Gemcitabine/Nab-paclitaxel for Perioperative Treatment of Resectable Pancreatic Ductal Adenocarcinoma
  Annals of Surgery. Sep, 2020  |   Pubmed ID: 32740235
• Institutional Variation in Recovery After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: An Opportunity for Enhanced Recovery Pathways
  Journal of Surgical Oncology. Oct, 2020  |   Pubmed ID: 32627199
• Adherence with Operative Standards in the Treatment of Gastric Cancer in the United States
  Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. May, 2020  |   Pubmed ID: 31745679
• Precision Chemoradiotherapy for HER2 Tumors Using Antibody Conjugates of an Auristatin Derivative with Reduced Cell Permeability
  Molecular Cancer Therapeutics. Jan, 2020  |   Pubmed ID: 31597712
• Optimal Surveillance Frequency After CRS/HIPEC for Appendiceal and Colorectal Neoplasms: A Multi-institutional Analysis of the US HIPEC Collaborative
  Annals of Surgical Oncology. Jan, 2020  |   Pubmed ID: 31243668
• Detection and Quantification of GPCR MRNA: An Assessment and Implications of Data from High-Content Methods
  ACS Omega. Oct, 2019  |   Pubmed ID: 31646252
• Association of an Acute Pain Service with Postoperative Outcomes Following Pancreaticoduodenectomy
  Journal of Perioperative Practice. Oct, 2019  |   Pubmed ID: 31524066
• Obstruction-Free Survival Following Operative Intervention for Malignant Bowel Obstruction in Appendiceal Cancer
  Annals of Surgical Oncology. Oct, 2019  |   Pubmed ID: 31190209
• Incidence, Risk Factors, and Prevention Strategies for Venous Thromboembolism After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
  Annals of Surgical Oncology. Jul, 2019  |   Pubmed ID: 31065960
• Primary Tumor Sidedness is Predictive of Survival in Colon Cancer Patients Treated with Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy: A US HIPEC Collaborative Study
  Annals of Surgical Oncology. Jul, 2019  |   Pubmed ID: 31016486
• Targeting LIF-mediated Paracrine Interaction for Pancreatic Cancer Therapy and Monitoring
  Nature. 05, 2019  |   Pubmed ID: 30996350
• MST1R Kinase Accelerates Pancreatic Cancer Progression Via Effects on Both Epithelial Cells and Macrophages
  Oncogene. 07, 2019  |   Pubmed ID: 30967626
• A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma
  Cell. Apr, 2019  |   Pubmed ID: 30955884
• Inhibition of Invasive Pancreatic Cancer: Restoring Cell Apoptosis by Activating Mitochondrial P53
  American Journal of Cancer Research. 2019  |   Pubmed ID: 30906636
• Exosomes from Pancreatic Juice: A Step Closer to the Holy Grail?
  Annals of Surgical Oncology. Jul, 2019  |   Pubmed ID: 30820788
• Does Primary Tumor Side Matter in Patients with Metastatic Colon Cancer Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy?
  Annals of Surgical Oncology. May, 2019  |   Pubmed ID: 30815802
• E47 Governs the MYC-CDKN1B/p27-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16 and Wild-Type P53
  Cellular and Molecular Gastroenterology and Hepatology. 2018  |   Pubmed ID: 30003124
• Preoperative Circulating Tumor DNA in Patients with Peritoneal Carcinomatosis is an Independent Predictor of Progression-Free Survival
  Annals of Surgical Oncology. Aug, 2018  |   Pubmed ID: 29948422
• GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic Targets
  Frontiers in Pharmacology. 2018  |   Pubmed ID: 29872392
• Cirrhosis is Not a Contraindication to Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in Highly Selected Patients
  World Journal of Surgical Oncology. Apr, 2018  |   Pubmed ID: 29699564
• Histologic Predictors of Recurrence in Mucinous Appendiceal Tumors with Peritoneal Dissemination After HIPEC
  Annals of Surgical Oncology. Mar, 2018  |   Pubmed ID: 29282599
• GPR68, a Proton-sensing GPCR, Mediates Interaction of Cancer-associated Fibroblasts and Cancer Cells
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2018  |   Pubmed ID: 29092903
• Factors Associated with 60-Day Readmission Following Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy
  Annals of Surgical Oncology. Jan, 2018  |   Pubmed ID: 29090402
• An Intergroup Randomized Phase II Study of Bevacizumab or Cetuximab in Combination with Gemcitabine and in Combination with Chemoradiation in Patients with Resected Pancreatic Carcinoma: A Trial of the ECOG-ACRIN Cancer Research Group (E2204)
  Oncology. 2018  |   Pubmed ID: 29040974
• Safety and Outcome Measures of First-in-Human Intraperitoneal α Radioimmunotherapy With 212Pb-TCMC-Trastuzumab
  American Journal of Clinical Oncology. Jul, 2018  |   Pubmed ID: 27906723
• Reprogramming Pancreatic Stellate Cells Via P53 Activation: A Putative Target for Pancreatic Cancer Therapy
  PloS One. 2017  |   Pubmed ID: 29211796
• Molecular Pathways: Targeting the Microenvironment of Liver Metastases
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2017  |   Pubmed ID: 28615370
• Overinterpretation is Common in Pathological Diagnosis of Appendix Cancer During Patient Referral for Oncologic Care
  PloS One. 2017  |   Pubmed ID: 28591173
• Hyaluronan-binding Peptide for Targeting Peritoneal Carcinomatosis
  Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. May, 2017  |   Pubmed ID: 28468593
• Effect of Selumetinib and MK-2206 Vs Oxaliplatin and Fluorouracil in Patients With Metastatic Pancreatic Cancer After Prior Therapy: SWOG S1115 Study Randomized Clinical Trial
  JAMA Oncology. Apr, 2017  |   Pubmed ID: 27978579
• Characterization of RON Protein Isoforms in Pancreatic Cancer: Implications for Biology and Therapeutics
  Oncotarget. Jul, 2016  |   Pubmed ID: 27323855
• Image-based Detection and Targeting of Therapy Resistance in Pancreatic Adenocarcinoma
  Nature. 06, 2016  |   Pubmed ID: 27281208
• Preoperative Modified FOLFIRINOX Treatment Followed by Capecitabine-Based Chemoradiation for Borderline Resectable Pancreatic Cancer: Alliance for Clinical Trials in Oncology Trial A021101
  JAMA Surgery. Aug, 2016  |   Pubmed ID: 27275632
• Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression
  Cancer Discovery. Aug, 2016  |   Pubmed ID: 27179037
• Urokinase-controlled Tumor Penetrating Peptide
  Journal of Controlled Release : Official Journal of the Controlled Release Society. 06, 2016  |   Pubmed ID: 27106816
• FRAX597, a PAK1 Inhibitor, Synergistically Reduces Pancreatic Cancer Growth when Combined with Gemcitabine
  BMC Cancer. Jan, 2016  |   Pubmed ID: 26774265
• A Novel Tool for Predicting Major Complications After Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy
  Annals of Surgical Oncology. May, 2016  |   Pubmed ID: 26678406
• Laparoscopy is Safe and Accurate to Evaluate Peritoneal Surface Metastasis Prior to Cytoreductive Surgery
  Annals of Surgical Oncology. May, 2016  |   Pubmed ID: 26542584
• A Novel Protein Isoform of the RON Tyrosine Kinase Receptor Transforms Human Pancreatic Duct Epithelial Cells
  Oncogene. Jun, 2016  |   Pubmed ID: 26477314
• A Tumor-penetrating Peptide Enhances Circulation-independent Targeting of Peritoneal Carcinomatosis
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Aug, 2015  |   Pubmed ID: 26071630
• SWOG S0809: A Phase II Intergroup Trial of Adjuvant Capecitabine and Gemcitabine Followed by Radiotherapy and Concurrent Capecitabine in Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Aug, 2015  |   Pubmed ID: 25964250
• Approach to Patients with Pancreatic Cancer Without Detectable Metastases
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2015  |   Pubmed ID: 25918279
• BAP1 Mutation is a Frequent Somatic Event in Peritoneal Malignant Mesothelioma
  Journal of Translational Medicine. Apr, 2015  |   Pubmed ID: 25889843
• Tumor Radiosensitization by Monomethyl Auristatin E: Mechanism of Action and Targeted Delivery
  Cancer Research. Apr, 2015  |   Pubmed ID: 25681274
• Laparoscopic Evacuation of Mucinous Ascites for Palliation of Pseudomyxoma Peritonei
  Annals of Surgical Oncology. May, 2015  |   Pubmed ID: 25395145
• Tumor-penetrating IRGD Peptide Inhibits Metastasis
  Molecular Cancer Therapeutics. Jan, 2015  |   Pubmed ID: 25392370
• Predictors of Progression in High-grade Appendiceal or Colorectal Peritoneal Carcinomatosis After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
  Annals of Surgical Oncology. May, 2015  |   Pubmed ID: 25145504
• Single-incision Laparoscopic Surgery Through an Ostomy Site: a Natural Approach by an Unnatural Orifice
  Surgical Laparoscopy, Endoscopy & Percutaneous Techniques. Feb, 2015  |   Pubmed ID: 24743670
• Enteral Stenting for Gastric Outlet Obstruction and Afferent Limb Syndrome Following Pancreaticoduodenectomy
  Annals of Gastroenterology. 2014  |   Pubmed ID: 25332208
• A Next-generation Dual-recombinase System for Time- and Host-specific Targeting of Pancreatic Cancer
  Nature Medicine. Nov, 2014  |   Pubmed ID: 25326799
• A Hypusine-eIF5A-PEAK1 Switch Regulates the Pathogenesis of Pancreatic Cancer
  Cancer Research. Nov, 2014  |   Pubmed ID: 25261239
• Correction: Genome-wide Mutational Landscape of Mucinous Carcinomatosis Peritonei of Appendiceal Origin
  Genome Medicine. 2014  |   Pubmed ID: 25228923
• Long-term Outcomes After Total Pancreatectomy and Islet Cell Autotransplantation: is It a Durable Operation?
  Annals of Surgery. Oct, 2014  |   Pubmed ID: 25203883
• Borderline Resectable Pancreatic Cancer: Definitions and Management
  World Journal of Gastroenterology. Aug, 2014  |   Pubmed ID: 25152577
• Dual Blockade of Epidermal Growth Factor Receptor and Insulin-like Growth Factor Receptor-1 Signaling in Metastatic Pancreatic Cancer: Phase Ib and Randomized Phase II Trial of Gemcitabine, Erlotinib, and Cixutumumab Versus Gemcitabine Plus Erlotinib (SWOG S0727)
  Cancer. Oct, 2014  |   Pubmed ID: 25041791
• Genome-wide Mutational Landscape of Mucinous Carcinomatosis Peritonei of Appendiceal Origin
  Genome Medicine. 2014  |   Pubmed ID: 24944587
• An Integrin β₃-KRAS-RalB Complex Drives Tumour Stemness and Resistance to EGFR Inhibition
  Nature Cell Biology. May, 2014  |   Pubmed ID: 24747441
• The RON Receptor Tyrosine Kinase in Pancreatic Cancer Pathogenesis and Its Potential Implications for Future Targeted Therapies
  Pancreas. Mar, 2014  |   Pubmed ID: 24518495
• Generation of Orthotopic Patient-derived Xenografts from Gastrointestinal Stromal Tumor
  Journal of Translational Medicine. Feb, 2014  |   Pubmed ID: 24507750
• Improved Perioperative Outcomes with Minimally Invasive Distal Pancreatectomy: Results from a Population-based Analysis
  JAMA Surgery. Mar, 2014  |   Pubmed ID: 24402232
• PI3Kα Activates Integrin α4β1 to Establish a Metastatic Niche in Lymph Nodes
  Proceedings of the National Academy of Sciences of the United States of America. May, 2013  |   Pubmed ID: 23671068
• A Dual-color Genetically Engineered Mouse Model for Multispectral Imaging of the Pancreatic Microenvironment
  Pancreas. Aug, 2013  |   Pubmed ID: 23648841
• Therapeutic Advances in Pancreatic Cancer
  Gastroenterology. Jun, 2013  |   Pubmed ID: 23622141
• Borderline Resectable Pancreatic Cancer: Need for Standardization and Methods for Optimal Clinical Trial Design
  Annals of Surgical Oncology. Aug, 2013  |   Pubmed ID: 23435609
• Changing the Way We Do Business: Recommendations to Accelerate Biomarker Development in Pancreatic Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2013  |   Pubmed ID: 23344262
• Chemokine CXCL12 Activates Dual CXCR4 and CXCR7-mediated Signaling Pathways in Pancreatic Cancer Cells
  Journal of Translational Medicine. Apr, 2012  |   Pubmed ID: 22472349
• The RON-receptor Regulates Pancreatic Cancer Cell Migration Through Phosphorylation-dependent Breakdown of the Hemidesmosome
  International Journal of Cancer. Oct, 2012  |   Pubmed ID: 22275185
• Disruption of P16 and Activation of Kras in Pancreas Increase Ductal Adenocarcinoma Formation and Metastasis in Vivo
  Oncotarget. Nov, 2011  |   Pubmed ID: 22113502
• IGF1-R Signals Through the RON Receptor to Mediate Pancreatic Cancer Cell Migration
  Carcinogenesis. Aug, 2011  |   Pubmed ID: 21565828
• Development of an Orthotopic Model of Invasive Pancreatic Cancer in an Immunocompetent Murine Host
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2010  |   Pubmed ID: 20534740
• The RON Tyrosine Kinase Receptor Regulates Vascular Endothelial Growth Factor Production in Pancreatic Cancer Cells
  Pancreas. Apr, 2010  |   Pubmed ID: 20358644
• Cystic Neoplasms of the Pancreas
  Surgical Oncology Clinics of North America. Apr, 2010  |   Pubmed ID: 20159515
• Pancreatic Cancer: Preface
  Surgical Oncology Clinics of North America. Apr, 2010  |   Pubmed ID: 20159512
• Silencing of RON Receptor Signaling Promotes Apoptosis and Gemcitabine Sensitivity in Pancreatic Cancers
  Cancer Research. Feb, 2010  |   Pubmed ID: 20103639
• Case Report: Focal Nesidioblastosis ("nesidioblastoma") in an Adult
  Human Pathology. Mar, 2010  |   Pubmed ID: 20004945
• Beyond the Ivory Tower: Outcomes Following Surgery for Ampullary Cancer
  Annals of Surgical Oncology. Jul, 2008  |   Pubmed ID: 18425553
• Neoadjuvant Therapy for Pancreatic Cancer
  Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Sep, 2008  |   Pubmed ID: 18259825
• Incidence, Natural History, and Patterns of Locoregional Recurrence in Gastric Cancer Patients Treated with Preoperative Chemoradiotherapy
  International Journal of Radiation Oncology, Biology, Physics. Jul, 2008  |   Pubmed ID: 18164837