Anne-Christine Bay-Jensen Nordic Bioscience Biography Publications Institution JoVE Articles Anne-Christine Bay-Jensen has not added a biography. If you are Anne-Christine Bay-Jensen and would like to personalize this page please email our Author Liaison for assistance. Publications Biochemical Markers in Osteoarthritis with Lessons Learned from Osteoporosis Clinical and Experimental Rheumatology. Sep-Oct, 2019 | Pubmed ID: 31621570 Associations Between Biomarkers of Bone and Cartilage Turnover, Gender, Pain Categories and Radiographic Severity in Knee Osteoarthritis Arthritis Research & Therapy. Sep, 2019 | Pubmed ID: 31481084 Serological Assessment of the Quality of Wound Healing Processes in Crohn's Disease Journal of Gastrointestinal and Liver Diseases : JGLD. Jun, 2019 | Pubmed ID: 31204415 Osteoarthritis Phenotypes and Novel Therapeutic Targets Biochemical Pharmacology. Jul, 2019 | Pubmed ID: 30831073 Association of Metabolites Reflecting Type III and VI Collagen Formation with Modified Rodnan Skin Score in Systemic Sclerosis - a Cross-sectional Study Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. Jun, 2019 | Pubmed ID: 30821519 GPDPLQ-A Type II Collagen Neo-Epitope Biomarker of Osteoclast- and Inflammation-Derived Cartilage Degradation in Vitro Scientific Reports. Feb, 2019 | Pubmed ID: 30816326 Metabolites of C-reactive Protein and Vimentin Are Associated with Disease Activity of Axial Spondyloarthritis Clinical and Experimental Rheumatology. May-Jun, 2019 | Pubmed ID: 30767876 Serological Biomarker Profiles of Rapidly Progressive Osteoarthritis in Tanezumab-treated Patients Osteoarthritis and Cartilage. Mar, 2019 | Pubmed ID: 30576794 Osteoarthritis Year in Review 2018: Biomarkers (biochemical Markers) Osteoarthritis and Cartilage. Mar, 2019 | Pubmed ID: 30552966 Molecular Taxonomy of Osteoarthritis for Patient Stratification, Disease Management and Drug Development: Biochemical Markers Associated with Emerging Clinical Phenotypes and Molecular Endotypes Current Opinion in Rheumatology. 01, 2019 | Pubmed ID: 30461544 The VICM Biomarker is Released from Activated Macrophages and Inhibited by Anti-GM-CSFRα-mAb Treatment in Rheumatoid Arthritis Patients Clinical and Experimental Rheumatology. Jan-Feb, 2019 | Pubmed ID: 30418117 Tofacitinib and TPCA-1 Exert Chondroprotective Effects on Extracellular Matrix Turnover in Bovine Articular Cartilage Ex Vivo Biochemical Pharmacology. Jul, 2019 | Pubmed ID: 30059674 Bone and Soft Tissue Turnover in Relation to All-cause Mortality in Postmenopausal Women The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Jun, 2019 | Pubmed ID: 30010805 Protein Biomarkers Associated with Pain Mechanisms in Osteoarthritis Journal of Proteomics. 01, 2019 | Pubmed ID: 29704569 Changes of Patient-reported Outcomes and Protein Fingerprint Biomarkers After Exercise Therapy for Axial Spondyloarthritis Clinical Rheumatology. Jan, 2019 | Pubmed ID: 28856518 Serum Biomarkers of Collagen Turnover As Potential Diagnostic Tools in Diffuse Systemic Sclerosis: A Cross-sectional Study PloS One. 2018 | Pubmed ID: 30507931 A Novel High Sensitivity Type II Collagen Blood-Based Biomarker, PRO-C2, for Assessment of Cartilage Formation International Journal of Molecular Sciences. Nov, 2018 | Pubmed ID: 30404167 Type IV Collagen Metabolism is Associated with Disease Activity, Radiographic Progression and Response to Tocilizumab in Rheumatoid Arthritis Clinical and Experimental Rheumatology. Sep-Oct, 2018 | Pubmed ID: 29745884 Aggrecanase Degradation of Type III Collagen is Associated with Clinical Knee Pain Clinical Biochemistry. Aug, 2018 | Pubmed ID: 29702061 Increased Remodelling of Interstitial Collagens and Basement Membrane is Suppressed by Treatment in Patients with Rheumatoid Arthritis: Serological Evaluation of a One-year Prospective Study of 149 Japanese Patients Clinical and Experimental Rheumatology. May-Jun, 2018 | Pubmed ID: 29465351 IL-6 Receptor Inhibition Modulates Type III Collagen and C-reactive Protein Degradation in Rheumatoid Arthritis Patients with an Inadequate Response to Anti-tumour Necrosis Factor Therapy: Analysis of Connective Tissue Turnover in the Tocilizumab RADIATE Study Clinical and Experimental Rheumatology. Jul-Aug, 2018 | Pubmed ID: 29465346 Identification of Pain Categories Associated with Change in Pain in Patients Receiving Placebo: Data from Two Phase 3 Randomized Clinical Trials in Symptomatic Knee Osteoarthritis BMC Musculoskeletal Disorders. 01, 2018 | Pubmed ID: 29343266 Blockade of GM-CSF Pathway Induced Sustained Suppression of Myeloid and T Cell Activities in Rheumatoid Arthritis Rheumatology (Oxford, England). 01, 2018 | Pubmed ID: 29069507 Biochemical Marker Discovery, Testing and Evaluation for Facilitating OA Drug Discovery and Development Drug Discovery Today. 02, 2018 | Pubmed ID: 29038075 Suppression of Active, but Not Total MMP-3, is Associated with Treatment Response in a Phase III Clinical Study of Rheumatoid Arthritis Clinical and Experimental Rheumatology. Jan-Feb, 2018 | Pubmed ID: 28850021 Soluble Biochemical Markers of Osteoarthritis: Are We Close to Using Them in Clinical Practice? Best Practice & Research. Clinical Rheumatology. 10, 2017 | Pubmed ID: 30509415 Sprifermin (rhFGF18) Modulates Extracellular Matrix Turnover in Cartilage Explants Ex Vivo Journal of Translational Medicine. Dec, 2017 | Pubmed ID: 29233174 Ulcerative Colitis, Crohn's Disease, and Irritable Bowel Syndrome Have Different Profiles of Extracellular Matrix Turnover, Which Also Reflects Disease Activity in Crohn's Disease PloS One. 2017 | Pubmed ID: 29028807 Excessive Matrix Metalloprotease-mediated Degradation of Interstitial Tissue (type I Collagen) Independently Predicts Short-term Survival in an Observational Study of Postmenopausal Women Diagnosed with Cancer Oncotarget. Aug, 2017 | Pubmed ID: 28881747 Unique Insight into Microenvironmental Changes in Colorectal Cancer: Assessment of Matrix Metalloprotease-mediated Molecular Changes in Human Colorectal Tumor Tissue and Corresponding Non-neoplastic Adjacent Tissue Oncology Letters. May, 2017 | Pubmed ID: 28529592 Biomarker of Extracellular Matrix Remodelling C1M and Proinflammatory Cytokine Interleukin 6 Are Related to Synovitis and Pain in End-stage Knee Osteoarthritis Patients Pain. 07, 2017 | Pubmed ID: 28333699 Nidogen-1 Degraded by Cathepsin S Can Be Quantified in Serum and is Associated with Non-Small Cell Lung Cancer Neoplasia (New York, N.Y.). 04, 2017 | Pubmed ID: 28282545 Type I and III Collagen Turnover is Increased in Axial Spondyloarthritis and Psoriatic Arthritis. Associations with Disease Activity and Diagnostic Capacity Clinical and Experimental Rheumatology. Jul-Aug, 2017 | Pubmed ID: 28240584 Remodeling of the Tumor Microenvironment Predicts Increased Risk of Cancer in Postmenopausal Women: The Prospective Epidemiologic Risk Factor (PERF I) Study Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. 09, 2016 | Pubmed ID: 27411352 Chondrocyte Activity is Increased in Psoriatic Arthritis and Axial Spondyloarthritis Arthritis Research & Therapy. 06, 2016 | Pubmed ID: 27306080 Intercritical Circulating Levels of Neo-epitopes Reflecting Matrixmetalloprotease-driven Degradation As Markers of Gout and Frequent Gout Attacks Rheumatology (Oxford, England). 09, 2016 | Pubmed ID: 27256715 Neo-Epitopes--Fragments of Cartilage and Connective Tissue Degradation in Early Rheumatoid Arthritis and Unclassified Arthritis PloS One. 2016 | Pubmed ID: 27019199 Synovitis Biomarkers: Ex Vivo Characterization of Three Biomarkers for Identification of Inflammatory Osteoarthritis Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 2015 | Pubmed ID: 26863055 Serum Cartilage Oligomeric Matrix Protein and Development of Radiographic and Painful Knee Osteoarthritis. A Community-based Cohort of Middle-aged Women Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 2015 | Pubmed ID: 26848781 Fragments of Citrullinated and MMP-degraded Vimentin and MMP-degraded Type III Collagen Are Novel Serological Biomarkers to Differentiate Crohn's Disease from Ulcerative Colitis Journal of Crohn's & Colitis. Oct, 2015 | Pubmed ID: 26188349 Clinical Drug Development Using Dynamic Biomarkers to Enable Personalized Health Care in COPD Chest. Jul, 2015 | Pubmed ID: 25856563 Novel Insights into the Function and Dynamics of Extracellular Matrix in Liver Fibrosis American Journal of Physiology. Gastrointestinal and Liver Physiology. May, 2015 | Pubmed ID: 25767261 Cartilage Turnover Reflected by Metabolic Processing of Type II Collagen: a Novel Marker of Anabolic Function in Chondrocytes International Journal of Molecular Sciences. Oct, 2014 | Pubmed ID: 25329619 Serum Biomarkers Reflecting Specific Tumor Tissue Remodeling Processes Are Valuable Diagnostic Tools for Lung Cancer Cancer Medicine. Oct, 2014 | Pubmed ID: 25044252 The Active Form of MMP-3 is a Marker of Synovial Inflammation and Cartilage Turnover in Inflammatory Joint Diseases BMC Musculoskeletal Disorders. Mar, 2014 | Pubmed ID: 24641725 Rheumatoid Arthritis: a Case for Personalized Health Care? Arthritis Care & Research. Sep, 2014 | Pubmed ID: 24470057 Extracellular Matrix Specific Protein Fingerprints Measured in Serum Can Separate Pancreatic Cancer Patients from Healthy Controls BMC Cancer. Nov, 2013 | Pubmed ID: 24261855 Quantification of "end Products" of Tissue Destruction in Inflammation May Reflect Convergence of Cytokine and Signaling Pathways -- Implications for Modern Clinical Chemistry Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. Aug, 2013 | Pubmed ID: 23721060 Extracellular Matrix Remodeling: the Common Denominator in Connective Tissue Diseases. Possibilities for Evaluation and Current Understanding of the Matrix As More Than a Passive Architecture, but a Key Player in Tissue Failure Assay and Drug Development Technologies. Mar, 2013 | Pubmed ID: 23046407 Investigation of Chondrocyte Hypertrophy and Cartilage Calcification in a Full-depth Articular Cartilage Explants Model Rheumatology International. Feb, 2013 | Pubmed ID: 22453523 Future Detection and Monitoring of Diabetes May Entail Analysis of Both β-cell Function and Volume: How Markers of β-cell Loss May Assist Journal of Translational Medicine. Oct, 2012 | Pubmed ID: 23110768 The Inhibitory Effect of Salmon Calcitonin on Tri-iodothyronine Induction of Early Hypertrophy in Articular Cartilage PloS One. 2012 | Pubmed ID: 22768225 Characterization of an Ex Vivo Femoral Head Model Assessed by Markers of Bone and Cartilage Turnover Cartilage. Jul, 2011 | Pubmed ID: 26069585 Diagnosis of Osteoarthritis by Cartilage Surface Smoothness Quantified Automatically from Knee MRI Cartilage. Jan, 2011 | Pubmed ID: 26069569 Molecular Serum and Urine Marker Repertoire Supporting Clinical Research on Joint Diseases Best Practice & Research. Clinical Rheumatology. Dec, 2011 | Pubmed ID: 22265266 Glucocorticoids Exert Context-dependent Effects on Cells of the Joint in Vitro Steroids. Dec, 2011 | Pubmed ID: 21855558 Biochemical Markers of Ongoing Joint Damage in Rheumatoid Arthritis--current and Future Applications, Limitations and Opportunities Arthritis Research & Therapy. Apr, 2011 | Pubmed ID: 21539724 Measurement of Matrix Metalloproteinase 9-mediated Collagen Type III Degradation Fragment As a Marker of Skin Fibrosis BMC Dermatology. Mar, 2011 | Pubmed ID: 21447148 Enzyme-linked Immunosorbent Assay (ELISAs) for Metalloproteinase Derived Type II Collagen Neoepitope, CIIM--increased Serum CIIM in Subjects with Severe Radiographic Osteoarthritis Clinical Biochemistry. Apr, 2011 | Pubmed ID: 21223960 Oral Salmon Calcitonin--pharmacology in Osteoporosis Expert Opinion on Biological Therapy. Nov, 2010 | Pubmed ID: 20932224 Novel Combinations of Post-Translational Modification (PTM) Neo-epitopes Provide Tissue-specific Biochemical Markers--are They the Cause or the Consequence of the Disease? Clinical Biochemistry. Jul, 2010 | Pubmed ID: 20381482 Investigation of the Direct Effects of Salmon Calcitonin on Human Osteoarthritic Chondrocytes BMC Musculoskeletal Disorders. Apr, 2010 | Pubmed ID: 20367884 Procollagen Type I N-terminal Propeptide (PINP) is a Marker for Fibrogenesis in Bile Duct Ligation-induced Fibrosis in Rats Fibrogenesis & Tissue Repair. Apr, 2010 | Pubmed ID: 20359335 Serum Markers of Liver Fibrosis: Combining the BIPED Classification and the Neo-epitope Approach in the Development of New Biomarkers Disease Markers. 2010 | Pubmed ID: 20164543 Application of Biochemical Markers in Development of Drugs for Treatment of Osteoarthritis Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. Feb, 2010 | Pubmed ID: 20085489 Aggrecanase- and Matrix Metalloproteinase-mediated Aggrecan Degradation is Associated with Different Molecular Characteristics of Aggrecan and Separated in Time Ex Vivo Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. May, 2010 | Pubmed ID: 20039789 Which Elements Are Involved in Reversible and Irreversible Cartilage Degradation in Osteoarthritis? Rheumatology International. Feb, 2010 | Pubmed ID: 19816688 Biochemical Markers of Joint Tissue Turnover Assay and Drug Development Technologies. Feb, 2010 | Pubmed ID: 19715454 Suppression of MMP Activity in Bovine Cartilage Explants Cultures Has Little if Any Effect on the Release of Aggrecanase-derived Aggrecan Fragments BMC Research Notes. Dec, 2009 | Pubmed ID: 20021645 The Disease Modifying Osteoarthritis Drug (DMOAD): Is It in the Horizon? Pharmacological Research. Jul, 2008 | Pubmed ID: 18590824 Un modèle de culture de tissu d'Ex Vivo du cartilage transformant dans les explants de genou de bovine Christian S. Thudium*1, Amalie Engstrom*1,2, Solveig S. Groen1, Morten A. Karsdal1, Anne-Christine Bay-Jensen1 1Nordic Bioscience, 2Department of Biomedical Sciences, University of Copenhagen JoVE 59467 Biology
Un modèle de culture de tissu d'Ex Vivo du cartilage transformant dans les explants de genou de bovine Christian S. Thudium*1, Amalie Engstrom*1,2, Solveig S. Groen1, Morten A. Karsdal1, Anne-Christine Bay-Jensen1 1Nordic Bioscience, 2Department of Biomedical Sciences, University of Copenhagen JoVE 59467 Biology