Anthony J. Koleske

Publications

• Platelet-derived Growth Factor Receptor Beta Activates Abl2 Via Direct Binding and Phosphorylation
  The Journal of Biological Chemistry. 07, 2021  |   Pubmed ID: 34144039
• Regulation of the NMDA Receptor by Its Cytoplasmic Domains: (How) is the Tail Wagging the Dog?
  Neuropharmacology. 09, 2021  |   Pubmed ID: 34097949
• Abl2:Cortactin Interactions Regulate Dendritic Spine Stability Via Control of a Stable Filamentous Actin Pool
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 04, 2021  |   Pubmed ID: 33622779
• Trio Family Proteins As Regulators of Cell Migration and Morphogenesis in Development and Disease - Mechanisms and Cellular Contexts
  Journal of Cell Science. 02, 2021  |   Pubmed ID: 33568469
• Functional Interactions of Ion Channels with the Actin Cytoskeleton: Does Coupling to Dynamic Actin Regulate NMDA Receptors?
  The Journal of Physiology. 01, 2021  |   Pubmed ID: 32034761
• Crystal Structure of a Guanine Nucleotide Exchange Factor Encoded by the Scrub Typhus Pathogen
  Proceedings of the National Academy of Sciences of the United States of America. 12, 2020  |   Pubmed ID: 33184172
• Two-color Nanoscopy of Organelles for Extended Times with HIDE Probes
  Nature Communications. 08, 2020  |   Pubmed ID: 32848153
• Neural Stem Cells Direct Axon Guidance Via Their Radial Fiber Scaffold
  Neuron. 09, 2020  |   Pubmed ID: 32707082
• ABL1, Overexpressed in Hepatocellular Carcinomas, Regulates Expression of NOTCH1 and Promotes Development of Liver Tumors in Mice
  Gastroenterology. 07, 2020  |   Pubmed ID: 32171747
• Regulation of MT Dynamics Via Direct Binding of an Abl Family Kinase
  The Journal of Cell Biology. 12, 2019  |   Pubmed ID: 31699690
• Integrin α5β1 Regulates PP2A Complex Assembly Through PDE4D in Atherosclerosis
  The Journal of Clinical Investigation. 08, 2019  |   Pubmed ID: 31408443
• Trio Haploinsufficiency Causes Neurodevelopmental Disease-Associated Deficits
  Cell Reports. 03, 2019  |   Pubmed ID: 30840899
• Transient Inhibition of P53 Homologs Protects Ovarian Function from Two Distinct Apoptotic Pathways Triggered by Anticancer Therapies
  Cell Death and Differentiation. 03, 2019  |   Pubmed ID: 29988075
• Abl2 is Recruited to Ventral Actin Waves Through Cytoskeletal Interactions to Promote Lamellipodium Extension
  Molecular Biology of the Cell. 11, 2018  |   Pubmed ID: 30256707
• Noonan Syndrome-Associated SHP2 Dephosphorylates GluN2B to Regulate NMDA Receptor Function
  Cell Reports. 08, 2018  |   Pubmed ID: 30089263
• Cortactin Stabilization of Actin Requires Actin-binding Repeats and Linker, is Disrupted by Specific Substitutions, and is Independent of Nucleotide State
  The Journal of Biological Chemistry. 08, 2018  |   Pubmed ID: 29929984
• A Role for the Non-Receptor Tyrosine Kinase Abl2/Arg in Experimental Neuroinflammation
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. 06, 2018  |   Pubmed ID: 29550892
• Analysis of Cellular Tyrosine Phosphorylation Via Chemical Rescue of Conditionally Active Abl Kinase
  Biochemistry. 02, 2018  |   Pubmed ID: 29341593
• The Vascular Endothelial Specific IL-4 Receptor Alpha-ABL1 Kinase Signaling Axis Regulates the Severity of IgE-mediated Anaphylactic Reactions
  The Journal of Allergy and Clinical Immunology. 10, 2018  |   Pubmed ID: 29157947
• The Repeat Region of Cortactin is Intrinsically Disordered in Solution
  Scientific Reports. 12, 2017  |   Pubmed ID: 29196701
• Corticosteroid-induced Dendrite Loss and Behavioral Deficiencies Can Be Blocked by Activation of Abl2/Arg Kinase
  Molecular and Cellular Neurosciences. 12, 2017  |   Pubmed ID: 29107098
• CNS Neurons Deposit Laminin α5 to Stabilize Synapses
  Cell Reports. Oct, 2017  |   Pubmed ID: 29091766
• Neurodevelopmental Disease-associated De Novo Mutations and Rare Sequence Variants Affect TRIO GDP/GTP Exchange Factor Activity
  Human Molecular Genetics. 12, 2017  |   Pubmed ID: 28973398
• Long-Term Live-Cell STED Nanoscopy of Primary and Cultured Cells with the Plasma Membrane HIDE Probe DiI-SiR
  Angewandte Chemie (International Ed. in English). 08, 2017  |   Pubmed ID: 28679029
• Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity
  ACS Chemical Neuroscience. 07, 2017  |   Pubmed ID: 28418645
• Phosphorylated Cortactin Recruits Vav2 Guanine Nucleotide Exchange Factor to Activate Rac3 and Promote Invadopodial Function in Invasive Breast Cancer Cells
  Molecular Biology of the Cell. May, 2017  |   Pubmed ID: 28356423
• Differential Expression of Cytoskeletal Regulatory Factors in the Adolescent Prefrontal Cortex: Implications for Cortical Development
  Journal of Neuroscience Research. 05, 2017  |   Pubmed ID: 27735056
• Arg Deficiency Does Not Influence the Course of Myelin Oligodendrocyte Glycoprotein (MOG35-55)-induced Experimental Autoimmune Encephalomyelitis
  Journal of Clinical & Cellular Immunology. 2016  |   Pubmed ID: 34527426
• Reciprocal Stabilization of ABL and TAZ Regulates Osteoblastogenesis Through Transcription Factor RUNX2
  The Journal of Clinical Investigation. Dec, 2016  |   Pubmed ID: 27797343
• The Src Kinases Hck, Fgr and Lyn Activate Arg to Facilitate IgG-mediated Phagocytosis and Leishmania Infection
  Journal of Cell Science. 08, 2016  |   Pubmed ID: 27358479
• Disruption of Coordinated Presynaptic and Postsynaptic Maturation Underlies the Defects in Hippocampal Synapse Stability and Plasticity in Abl2/Arg-Deficient Mice
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 06, 2016  |   Pubmed ID: 27335408
• SNARE Complex Dysfunction: A Unifying Hypothesis for Schizophrenia
  Biological Psychiatry. Sep, 2015  |   Pubmed ID: 26296424
• A Phase Ib Multiple Ascending Dose Study of the Safety, Tolerability, and Central Nervous System Availability of AZD0530 (saracatinib) in Alzheimer's Disease
  Alzheimer's Research & Therapy. 2015  |   Pubmed ID: 25874001
• Structure of the ABL2/ARG Kinase in Complex with Dasatinib
  Acta Crystallographica. Section F, Structural Biology Communications. Apr, 2015  |   Pubmed ID: 25849507
• Direct Interactions with the Integrin β1 Cytoplasmic Tail Activate the Abl2/Arg Kinase
  The Journal of Biological Chemistry. Mar, 2015  |   Pubmed ID: 25694433
• Abl2/Abl-related Gene Stabilizes Actin Filaments, Stimulates Actin Branching by Actin-related Protein 2/3 Complex, and Promotes Actin Filament Severing by Cofilin
  The Journal of Biological Chemistry. Feb, 2015  |   Pubmed ID: 25540195
• Adolescent Cocaine Exposure Simplifies Orbitofrontal Cortical Dendritic Arbors
  Frontiers in Pharmacology. 2014  |   Pubmed ID: 25452728
• ECM Receptors in Neuronal Structure, Synaptic Plasticity, and Behavior
  Progress in Brain Research. 2014  |   Pubmed ID: 25410355
• Extracellular Matrix Control of Dendritic Spine and Synapse Structure and Plasticity in Adulthood
  Frontiers in Neuroanatomy. 2014  |   Pubmed ID: 25368556
• Two Amino Acid Residues Confer Different Binding Affinities of Abelson Family Kinase SRC Homology 2 Domains for Phosphorylated Cortactin
  The Journal of Biological Chemistry. Jul, 2014  |   Pubmed ID: 24891505
• Ablation of ErbB4 from Excitatory Neurons Leads to Reduced Dendritic Spine Density in Mouse Prefrontal Cortex
  The Journal of Comparative Neurology. Oct, 2014  |   Pubmed ID: 24752666
• Metabotropic Glutamate Receptor 5 is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein
  Neuron. Sep, 2013  |   Pubmed ID: 24012003
• Arg Kinase Signaling in Dendrite and Synapse Stabilization Pathways: Memory, Cocaine Sensitivity, and Stress
  The International Journal of Biochemistry & Cell Biology. Nov, 2013  |   Pubmed ID: 23916785
• Molecular Mechanisms of Dendrite Stability
  Nature Reviews. Neuroscience. Aug, 2013  |   Pubmed ID: 23839597
• WAVE2 Regulates Epithelial Morphology and Cadherin Isoform Switching Through Regulation of Twist and Abl
  PloS One. 2013  |   Pubmed ID: 23691243
• Integrin α3 is Required for Late Postnatal Stability of Dendrite Arbors, Dendritic Spines and Synapses, and Mouse Behavior
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2013  |   Pubmed ID: 23595732
• β1 Integrin Regulates Arg to Promote Invadopodial Maturation and Matrix Degradation
  Molecular Biology of the Cell. Jun, 2013  |   Pubmed ID: 23552693
• Corticosteroid-induced Neural Remodeling Predicts Behavioral Vulnerability and Resilience
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2013  |   Pubmed ID: 23407965
• Abl2/Arg Controls Dendritic Spine and Dendrite Arbor Stability Via Distinct Cytoskeletal Control Pathways
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2013  |   Pubmed ID: 23365224
• Delayed Amyloid Plaque Deposition and Behavioral Deficits in Outcrossed AβPP/PS1 Mice
  The Journal of Comparative Neurology. Apr, 2013  |   Pubmed ID: 23047754
• Arg/Abl2 Promotes Invasion and Attenuates Proliferation of Breast Cancer in Vivo
  Oncogene. May, 2013  |   Pubmed ID: 22777352
• Action Control is Mediated by Prefrontal BDNF and Glucocorticoid Receptor Binding
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2012  |   Pubmed ID: 23185000
• A Peptide Photoaffinity Probe Specific for the Active Conformation of the Abl Tyrosine Kinase
  Chembiochem : a European Journal of Chemical Biology. Nov, 2012  |   Pubmed ID: 23081945
• Met Acts Through Abl to Regulate P53 Transcriptional Outcomes and Cell Survival in the Developing Liver
  Journal of Hepatology. Dec, 2012  |   Pubmed ID: 22889954
• Arg/Abl2 Modulates the Affinity and Stoichiometry of Binding of Cortactin to F-actin
  Biochemistry. Aug, 2012  |   Pubmed ID: 22849492
• The Abl and Arg Kinases Mediate Distinct Modes of Phagocytosis and Are Required for Maximal Leishmania Infection
  Molecular and Cellular Biology. Aug, 2012  |   Pubmed ID: 22665498
• Cortactin in Cell Migration and Cancer at a Glance
  Journal of Cell Science. Apr, 2012  |   Pubmed ID: 22566665
• Arg Kinase Regulates Prefrontal Dendritic Spine Refinement and Cocaine-induced Plasticity
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2012  |   Pubmed ID: 22396406
• Integrin β1 Signals Through Arg to Regulate Postnatal Dendritic Arborization, Synapse Density, and Behavior
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2012  |   Pubmed ID: 22357865
• Lysozyme Contamination Facilitates Crystallization of a Heterotrimeric Cortactin-Arg-lysozyme Complex
  Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Feb, 2012  |   Pubmed ID: 22297987
• Cortactin Phosphorylation Regulates Cell Invasion Through a PH-dependent Pathway
  The Journal of Cell Biology. Nov, 2011  |   Pubmed ID: 22105349
• ErbB4 Localization to Interneurons: Clearer Insights into Schizophrenia Pathology
  Biological Psychiatry. Oct, 2011  |   Pubmed ID: 21924131
• Invadopodia: RhoC Runs Rings Around Cofilin
  Current Biology : CB. Apr, 2011  |   Pubmed ID: 21514509
• Cell Adhesion Signaling Pathways: First Responders to Cocaine Exposure?
  Communicative & Integrative Biology. Jan, 2011  |   Pubmed ID: 21509173
• The Vacuolar-ATPase Modulates Matrix Metalloproteinase Isoforms in Human Pancreatic Cancer
  Laboratory Investigation; a Journal of Technical Methods and Pathology. May, 2011  |   Pubmed ID: 21339745
• An EGFR-Src-Arg-cortactin Pathway Mediates Functional Maturation of Invadopodia and Breast Cancer Cell Invasion
  Cancer Research. Mar, 2011  |   Pubmed ID: 21257711
• Specific Tyrosine Phosphorylation Sites on Cortactin Regulate Nck1-dependent Actin Polymerization in Invadopodia
  Journal of Cell Science. Nov, 2010  |   Pubmed ID: 20971703
• Phosphorylation by the C-Abl Protein Tyrosine Kinase Inhibits Parkin's Ubiquitination and Protective Function
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2010  |   Pubmed ID: 20823226
• The Abl and Arg Non-receptor Tyrosine Kinases Regulate Different Zones of Stress Fiber, Focal Adhesion, and Contractile Network Localization in Spreading Fibroblasts
  Cytoskeleton (Hoboken, N.J.). Oct, 2010  |   Pubmed ID: 20737438
• Increased Dendrite Branching in AbetaPP/PS1 Mice and Elongation of Dendrite Arbors by Fasudil Administration
  Journal of Alzheimer's Disease : JAD. 2010  |   Pubmed ID: 20413901
• Mechanisms of Synapse and Dendrite Maintenance and Their Disruption in Psychiatric and Neurodegenerative Disorders
  Annual Review of Neuroscience. 2010  |   Pubmed ID: 20367247
• Synaptic Clustering of PSD-95 is Regulated by C-Abl Through Tyrosine Phosphorylation
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2010  |   Pubmed ID: 20220006
• Regulation of Actin Polymerization and Adhesion-dependent Cell Edge Protrusion by the Abl-related Gene (Arg) Tyrosine Kinase and N-WASp
  Biochemistry. Mar, 2010  |   Pubmed ID: 20146487
• Loss of Dendrite Stabilization by the Abl-related Gene (Arg) Kinase Regulates Behavioral Flexibility and Sensitivity to Cocaine
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2009  |   Pubmed ID: 19805386
• Regulation of Cell Migration and Morphogenesis by Abl-family Kinases: Emerging Mechanisms and Physiological Contexts
  Journal of Cell Science. Oct, 2009  |   Pubmed ID: 19759284
• Cortactin Regulates Cofilin and N-WASp Activities to Control the Stages of Invadopodium Assembly and Maturation
  The Journal of Cell Biology. Aug, 2009  |   Pubmed ID: 19704022
• N-myristoylated C-Abl Tyrosine Kinase Localizes to the Endoplasmic Reticulum Upon Binding to an Allosteric Inhibitor
  The Journal of Biological Chemistry. Oct, 2009  |   Pubmed ID: 19679652
• Arg Interacts with Cortactin to Promote Adhesion-dependent Cell Edge Protrusion
  The Journal of Cell Biology. May, 2009  |   Pubmed ID: 19414610
• T Cell Survival and Function Requires the C-Abl Tyrosine Kinase
  Cell Cycle (Georgetown, Tex.). Dec, 2008  |   Pubmed ID: 19098427
• Enhancement of ABL Kinase Catalytic Efficiency by a Direct Binding Regulator is Independent of Other Regulatory Mechanisms
  The Journal of Biological Chemistry. Nov, 2008  |   Pubmed ID: 18796434
• The C-Abl Tyrosine Kinase Regulates Actin Remodeling at the Immune Synapse
  Blood. Jul, 2008  |   Pubmed ID: 18305217
• Inhibition of Rho Via Arg and P190RhoGAP in the Postnatal Mouse Hippocampus Regulates Dendritic Spine Maturation, Synapse and Dendrite Stability, and Behavior
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2007  |   Pubmed ID: 17928439
• Use of a Chemical Genetic Technique to Identify Myosin IIb As a Substrate of the Abl-related Gene (Arg) Tyrosine Kinase
  Biochemistry. Oct, 2007  |   Pubmed ID: 17892306
• Dissecting Kinase Signaling Pathways
  Drug Discovery Today. Sep, 2007  |   Pubmed ID: 17826684
• The Abl-related Gene Tyrosine Kinase Acts Through P190RhoGAP to Inhibit Actomyosin Contractility and Regulate Focal Adhesion Dynamics Upon Adhesion to Fibronectin
  Molecular Biology of the Cell. Oct, 2007  |   Pubmed ID: 17652459
• A Critical Role for Cortactin Phosphorylation by Abl-family Kinases in PDGF-induced Dorsal-wave Formation
  Current Biology : CB. Mar, 2007  |   Pubmed ID: 17306540
• Integrin Signaling Through Arg Activates P190RhoGAP by Promoting Its Binding to P120RasGAP and Recruitment to the Membrane
  Molecular Biology of the Cell. Nov, 2006  |   Pubmed ID: 16971514
• Integrin-mediated Dendrite Branch Maintenance Requires Abelson (Abl) Family Kinases
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2005  |   Pubmed ID: 15987940
• The Abl-related Gene (Arg) Requires Its F-actin-microtubule Cross-linking Activity to Regulate Lamellipodial Dynamics During Fibroblast Adhesion
  The Journal of Cell Biology. May, 2004  |   Pubmed ID: 15138293
• Adhesion-dependent Regulation of P190RhoGAP in the Developing Brain by the Abl-related Gene Tyrosine Kinase
  Current Biology : CB. Apr, 2004  |   Pubmed ID: 15084284
• Bidirectional Signaling Links the Abelson Kinases to the Platelet-derived Growth Factor Receptor
  Molecular and Cellular Biology. Mar, 2004  |   Pubmed ID: 14993293
• How Do Abl Family Kinases Regulate Cell Shape and Movement?
  Trends in Cell Biology. Jan, 2004  |   Pubmed ID: 14729179
• Do Filopodia Enable the Growth Cone to Find Its Way?
  Science's STKE : Signal Transduction Knowledge Environment. May, 2003  |   Pubmed ID: 12759482
• Two Distinct Phosphorylation Pathways Have Additive Effects on Abl Family Kinase Activation
  Molecular and Cellular Biology. Jun, 2003  |   Pubmed ID: 12748290
• Abl Family Nonreceptor Tyrosine Kinases Modulate Short-term Synaptic Plasticity
  Journal of Neurophysiology. Mar, 2003  |   Pubmed ID: 12626632
• The Abl-related Gene (Arg) Nonreceptor Tyrosine Kinase Uses Two F-actin-binding Domains to Bundle F-actin
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2001  |   Pubmed ID: 11752434
• Essential Roles for the Abl and Arg Tyrosine Kinases in Neurulation
  Neuron. Dec, 1998  |   Pubmed ID: 9883720