Csaba Hegedűs Department of Medical Chemistry, Faculty of Medicine University of Debrecen Biography Publications Institution JoVE Articles Csaba Hegedűs has not added a biography. If you are Csaba Hegedűs and would like to personalize this page please email our Author Liaison for assistance. Publications PARP14 Contributes to the Development of the Tumor-Associated Macrophage Phenotype International Journal of Molecular Sciences. Mar, 2024 | Pubmed ID: 38612413 CHANGES IN THE ULTRASTRUCTURAL ELEMENTS OF PERIODONTAL NEUROTROPHY UNDER CONDITIONS OF ACUTE SIMPLE COAGULATION DYSTROPHY IN THE EXPERIMENT Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego. 2023 | Pubmed ID: 38207062 Autoimmune Amelogenesis Imperfecta in Patients with APS-1 and Coeliac Disease Nature. Dec, 2023 | Pubmed ID: 37993717 EVALUATION OF DYNAMIC CHANGES IN THE MICROCIRCULATION OF THE MUCOSA IN THE ZONE OF DENTAL IMPLANTATION WITH IMMEDIATE INTRAOPERATIVE LOAD Wiadomosci Lekarskie (Warsaw, Poland : 1960). 2023 | Pubmed ID: 37898923 Plasmonic Effect of Gold-Patchy Silica Nanoparticles on Green Light-Photopolymerizable Dental Resin Nanomaterials (Basel, Switzerland). Sep, 2023 | Pubmed ID: 37764583 Identification of Bacterial Metabolites Modulating Breast Cancer Cell Proliferation and Epithelial-Mesenchymal Transition Molecules (Basel, Switzerland). Aug, 2023 | Pubmed ID: 37570868 Migration of Myogenic Cells Is Highly Influenced by Cytoskeletal Septin7 Cells. Jul, 2023 | Pubmed ID: 37508490 β-Tricalcium Phosphate-Modified Aerogel Containing PVA/Chitosan Hybrid Nanospun Scaffolds for Bone Regeneration International Journal of Molecular Sciences. Apr, 2023 | Pubmed ID: 37108742 Examination of Preferences for COVID-19 Vaccines in Hungary Based on Their Properties-Examining the Impact of Pandemic Awareness with a Hybrid Choice Approach International Journal of Environmental Research and Public Health. Jan, 2023 | Pubmed ID: 36674026 KDM1A Inhibition Increases UVA Toxicity and Enhances Photodynamic Therapy Efficacy Photodermatology, Photoimmunology & Photomedicine. May, 2023 | Pubmed ID: 35968606 OGG1 Inhibition Reduces Acinar Cell Injury in a Mouse Model of Acute Pancreatitis Biomedicines. Oct, 2022 | Pubmed ID: 36289805 Novel Polyurethane Scaffolds Containing Sucrose Crosslinker for Dental Application International Journal of Molecular Sciences. Jul, 2022 | Pubmed ID: 35887250 Tricetin Reduces Inflammation and Acinar Cell Injury in Cerulein-Induced Acute Pancreatitis: The Role of Oxidative Stress-Induced DNA Damage Signaling Biomedicines. Jun, 2022 | Pubmed ID: 35740393 COMPARATIVE EVALUATION OF CLINICAL APPLICATION OF MONOLITHIC AND FOLDING IMPLANTS IN REHABILITATION OF ELDERLY PATIENTS WITH VARIOUS DEGREES OF ATROPHY OF ALVEOLAR PROCESSES Wiadomosci Lekarskie (Warsaw, Poland : 1960). 2022 | Pubmed ID: 35633319 Combined Release of Antiseptic and Antibiotic Drugs from Visible Light Polymerized Biodegradable Nanocomposite Hydrogels for Periodontitis Treatment Pharmaceutics. Apr, 2022 | Pubmed ID: 35631542 The Effect of Heat Treatment of β-Tricalcium Phosphate-Containing Silica-Based Bioactive Aerogels on the Cellular Metabolism and Proliferation of MG63 Cells Biomedicines. Mar, 2022 | Pubmed ID: 35327463 The Multitargeted Receptor Tyrosine Kinase Inhibitor Sunitinib Induces Resistance of HER2 Positive Breast Cancer Cells to Trastuzumab-mediated ADCC Cancer Immunology, Immunotherapy : CII. Sep, 2022 | Pubmed ID: 35066605 IMMEDIATE IMPLANTATION AND AESTHETIC COMPONENT AS A RESULT OF SUCCESSFUL FORECAST TREATMENT Wiadomosci Lekarskie (Warsaw, Poland : 1960). 2021 | Pubmed ID: 34923467 The Effect of the PVA/Chitosan/Citric Acid Ratio on the Hydrophilicity of Electrospun Nanofiber Meshes Polymers. Oct, 2021 | Pubmed ID: 34685316 NMNAT1 Is a Survival Factor in Actinomycin D-Induced Osteosarcoma Cell Death International Journal of Molecular Sciences. Aug, 2021 | Pubmed ID: 34445574 Effect of Inducible BMP-7 Expression on the Osteogenic Differentiation of Human Dental Pulp Stem Cells International Journal of Molecular Sciences. Jun, 2021 | Pubmed ID: 34201124 Evaluation of the Histomorphometric and Micromorphometric Performance of a Serum Albumin-Coated Bone Allograft Combined with A-PRF for Early and Conventional Healing Protocols After Maxillary Sinus Augmentation: A Randomized Clinical Trial Materials (Basel, Switzerland). Apr, 2021 | Pubmed ID: 33917513 Poly(ADP-Ribose) Polymerase 1 Promotes Inflammation and Fibrosis in a Mouse Model of Chronic Pancreatitis International Journal of Molecular Sciences. Mar, 2021 | Pubmed ID: 33808340 Effects of Different Surface Treatments and Adhesive Self-etch Functional Monomers on the Repair of Bulk Fill Composites: A Randomised Controlled Study Journal of Dentistry. May, 2021 | Pubmed ID: 33766513 Electrosprayed Calcium Silicate Nanoparticle-coated Titanium Implant with Improved Antibacterial Activity and Osteogenesis Colloids and Surfaces. B, Biointerfaces. Jun, 2021 | Pubmed ID: 33743444 Inhibitors of Nucleotide Excision Repair Decrease UVB-Induced Mutagenesis-An In Vitro Study International Journal of Molecular Sciences. Feb, 2021 | Pubmed ID: 33562002 Optimization of Plasmonic Gold Nanoparticle Concentration in Green LED Light Active Dental Photopolymer Polymers. Jan, 2021 | Pubmed ID: 33467688 High-content Screening Identifies Inhibitors of Oxidative Stress-induced Parthanatos: Cytoprotective and Anti-inflammatory Effects of Ciclopirox British Journal of Pharmacology. Mar, 2021 | Pubmed ID: 33332573 Cyclobutane Pyrimidine Dimers from UVB Exposure Induce a Hypermetabolic State in Keratinocytes Via Mitochondrial Oxidative Stress Redox Biology. Jan, 2021 | Pubmed ID: 33264701 SIRT1 Activation by L. (Horsetail) Modulates Insulin Sensitivity in Streptozotocin Induced Diabetic Rats Molecules (Basel, Switzerland). May, 2020 | Pubmed ID: 32486051 Targeting Nuclear NAD Synthesis Inhibits DNA Repair, Impairs Metabolic Adaptation and Increases Chemosensitivity of U-2OS Osteosarcoma Cells Cancers. May, 2020 | Pubmed ID: 32392755 Retinoprotection by BGP-15, a Hydroximic Acid Derivative, in a Type II Diabetic Rat Model Compared to Glibenclamide, Metformin, and Pioglitazone International Journal of Molecular Sciences. Mar, 2020 | Pubmed ID: 32204537 Effect of Inducible Bone Morphogenetic Protein 2 Expression on the Osteogenic Differentiation of Dental Pulp Stem Cells in Vitro Bone. Mar, 2020 | Pubmed ID: 31884130 Poly(ADP-ribose) Polymerase-1 Depletion Enhances the Severity of Inflammation in an Imiquimod-induced Model of Psoriasis Experimental Dermatology. Jan, 2020 | Pubmed ID: 31755591 PARP1 Inhibition Augments UVB-Mediated Mitochondrial Changes-Implications for UV-Induced DNA Repair and Photocarcinogenesis Cancers. Dec, 2019 | Pubmed ID: 31861350 Anthocyanin-Rich Sour Cherry Extract Attenuates the Lipopolysaccharide-Induced Endothelial Inflammatory Response Molecules (Basel, Switzerland). Sep, 2019 | Pubmed ID: 31546579 Spilanthol Inhibits Inflammatory Transcription Factors and INOS Expression in Macrophages and Exerts Anti-inflammatory Effects in Dermatitis and Pancreatitis International Journal of Molecular Sciences. Sep, 2019 | Pubmed ID: 31484391 Lithocholic Acid, a Metabolite of the Microbiome, Increases Oxidative Stress in Breast Cancer Cancers. Aug, 2019 | Pubmed ID: 31461945 Effect of Anthocyanin-Rich Tart Cherry Extract on Inflammatory Mediators and Adipokines Involved in Type 2 Diabetes in a High Fat Diet Induced Obesity Mouse Model Nutrients. Aug, 2019 | Pubmed ID: 31438590 Effectiveness of Parameters in Quantifying Root Canal Morphology Change After Instrumentation with the Aid of a Microcomputed Tomography BioMed Research International. 2019 | Pubmed ID: 31355288 Recent Advances in Investigation, Prevention, and Management of Healthcare-Associated Infections (HAIs): Resistant Multidrug Strain Colonization and Its Risk Factors in an Intensive Care Unit of a University Hospital BioMed Research International. 2019 | Pubmed ID: 31321231 Investigation of Silver Nanoparticles on Titanium Surface Created by Ion Implantation Technology International Journal of Nanomedicine. 2019 | Pubmed ID: 31308654 Programmed Necrotic Cell Death of Macrophages: Focus on Pyroptosis, Necroptosis, and Parthanatos Redox Biology. Sep, 2019 | Pubmed ID: 31212216 Diosgenin and Its Fenugreek Based Biological Matrix Affect Insulin Resistance and Anabolic Hormones in a Rat Based Insulin Resistance Model BioMed Research International. 2019 | Pubmed ID: 31080828 A Randomised Controlled Study on the Effects of Different Surface Treatments and Adhesive Self-etch Functional Monomers on the Immediate Repair Bond Strength and Integrity of the Repaired Resin Composite Interface Journal of Dentistry. Jun, 2019 | Pubmed ID: 31054292 Silymarin: Friend or Foe of UV Exposed Keratinocytes? Molecules (Basel, Switzerland). Apr, 2019 | Pubmed ID: 31035502 Calcium Silicate Layer on Titanium Fabricated by Electrospray Deposition Materials Science & Engineering. C, Materials for Biological Applications. May, 2019 | Pubmed ID: 30813041 LPS Protects Macrophages from AIF-independent Parthanatos by Downregulation of PARP1 Expression, Induction of SOD2 Expression, and a Metabolic Shift to Aerobic Glycolysis Free Radical Biology & Medicine. Feb, 2019 | Pubmed ID: 30502458 Isolation of Allithiamine from Hungarian Red Sweet Pepper Seed () Heliyon. Dec, 2018 | Pubmed ID: 30582034 Redox Profiling Reveals Clear Differences Between Molecular Patterns of Wound Fluids from Acute and Chronic Wounds Oxidative Medicine and Cellular Longevity. 2018 | Pubmed ID: 30581533 Ultraviolet Radiation-mediated Development of Cutaneous Melanoma: An Update Journal of Photochemistry and Photobiology. B, Biology. Aug, 2018 | Pubmed ID: 29936410 Redox Control of Cancer Cell Destruction Redox Biology. Jun, 2018 | Pubmed ID: 29477046 Diverse Effect of BMP-2 Homodimer on Mesenchymal Progenitors of Different Origin Human Cell. Apr, 2018 | Pubmed ID: 29442285 Interplay of Myosin Phosphatase and Protein Phosphatase-2A in the Regulation of Endothelial Nitric-oxide Synthase Phosphorylation and Nitric Oxide Production Scientific Reports. Mar, 2017 | Pubmed ID: 28300193 Nitric Oxide-coupled Signaling in Odor Elicited Molecular Events in the Olfactory Center of the Terrestrial Snail, Helix Pomatia Cellular Signalling. Jan, 2017 | Pubmed ID: 27884734 Enhanced Physicochemical and Biological Properties of Ion-Implanted Titanium Using Electron Cyclotron Resonance Ion Sources Materials (Basel, Switzerland). Jan, 2016 | Pubmed ID: 28787825 Diabetes-induced Oxidative Stress in the Vitreous Humor Redox Biology. Oct, 2016 | Pubmed ID: 27454767 The PARP Inhibitor PJ-34 Sensitizes Cells to UVA-induced Phototoxicity by a PARP Independent Mechanism Mutation Research. Aug, 2016 | Pubmed ID: 27427773 Transfection of Human Keratinocytes with Nucleoside-Modified MRNA Encoding CPD-Photolyase to Repair DNA Damage Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 27236802 Effect of Long-term Olanzapine Treatment on Meal-induced Insulin Sensitization and on Gastrointestinal Peptides in Female Sprague-Dawley Rats Journal of Psychopharmacology (Oxford, England). Dec, 2015 | Pubmed ID: 26349558 Oral Health-related Quality of Life After Prosthetic Rehabilitation: a Longitudinal Study with the OHIP Questionnaire Health and Quality of Life Outcomes. 2015 | Pubmed ID: 26156102 High Throughput Screening Identifies a Novel Compound Protecting Cardiomyocytes from Doxorubicin-Induced Damage Oxidative Medicine and Cellular Longevity. 2015 | Pubmed ID: 26137186 Poly(ADP-ribose) in the Bone: from Oxidative Stress Signal to Structural Element Free Radical Biology & Medicine. May, 2015 | Pubmed ID: 25660995 Effects of Non-toxic Zinc Exposure on Human Epidermal Keratinocytes Metallomics : Integrated Biometal Science. Mar, 2015 | Pubmed ID: 25659595 Meal-induced Insulin Sensitization is Preserved After Acute Olanzapine Administration in Female Sprague-Dawley Rats Naunyn-Schmiedeberg's Archives of Pharmacology. May, 2015 | Pubmed ID: 25644372 Inputs and Outputs of Poly(ADP-ribosyl)ation: Relevance to Oxidative Stress Redox Biology. 2014 | Pubmed ID: 25460733 The Role of P38 Signaling and Poly(ADP-ribosyl)ation-induced Metabolic Collapse in the Osteogenic Differentiation-coupled Cell Death Pathway Free Radical Biology & Medicine. Nov, 2014 | Pubmed ID: 25078118 Activation of Poly(ADP-ribose) Polymerase-1 Delays Wound Healing by Regulating Keratinocyte Migration and Production of Inflammatory Mediators Molecular Medicine (Cambridge, Mass.). Aug, 2014 | Pubmed ID: 25014793 Identification of PPARγ Ligands with One-dimensional Drug Profile Matching Drug Design, Development and Therapy. 2013 | Pubmed ID: 24039401 Glycogen Phosphorylase Inhibitor N-(3,5-dimethyl-Benzoyl)-N'-(β-D-glucopyranosyl)urea Improves Glucose Tolerance Under Normoglycemic and Diabetic Conditions and Rearranges Hepatic Metabolism PloS One. 2013 | Pubmed ID: 23936011 Cytoprotective Dibenzoylmethane Derivatives Protect Cells from Oxidative Stress-induced Necrotic Cell Death Pharmacological Research. Jun, 2013 | Pubmed ID: 23523665 The Role of Acute Hyperinsulinemia in the Development of Cardiac Arrhythmias Naunyn-Schmiedeberg's Archives of Pharmacology. May, 2013 | Pubmed ID: 23474828 In Vivo Application of a Small Molecular Weight Antifungal Protein of Penicillium Chrysogenum (PAF) Toxicology and Applied Pharmacology. May, 2013 | Pubmed ID: 23466426 3-Aminobenzamide Protects Primary Human Keratinocytes from UV-induced Cell Death by a Poly(ADP-ribosyl)ation Independent Mechanism Biochimica Et Biophysica Acta. Mar, 2013 | Pubmed ID: 23246565 Composition and Characterization of in Situ Usable Light Cured Dental Drug Delivery Hydrogel System Journal of Materials Science. Materials in Medicine. Mar, 2013 | Pubmed ID: 23229574 Poly(ADP-ribosyl)ation is a Survival Mechanism in Cigarette Smoke-induced and Hydrogen Peroxide-mediated Cell Death Free Radical Biology & Medicine. Nov, 2012 | Pubmed ID: 22964577 Beneficial Cardiac Effects of Cicletanine in Conscious Rabbits with Metabolic Syndrome Journal of Cardiovascular Pharmacology. Aug, 2012 | Pubmed ID: 22622233 Poly(ADP-ribose) Polymerase-2 Depletion Reduces Doxorubicin-induced Damage Through SIRT1 Induction Cardiovascular Research. Dec, 2011 | Pubmed ID: 21921080 Genetic Ablation of PARP-1 Protects Against Oxazolone-induced Contact Hypersensitivity by Modulating Oxidative Stress The Journal of Investigative Dermatology. Nov, 2010 | Pubmed ID: 20613774 Protein Kinase C Protects from DNA Damage-induced Necrotic Cell Death by Inhibiting Poly(ADP-ribose) Polymerase-1 FEBS Letters. May, 2008 | Pubmed ID: 18439913 Protein Tyrosine Nitration and Poly(ADP-ribose) Polymerase Activation in N-methyl-N-nitro-N-nitrosoguanidine-treated Thymocytes: Implication for Cytotoxicity Toxicology Letters. May, 2007 | Pubmed ID: 17428624 In Vitro FT-IR Study of the Effects of Hydrogen Peroxide on Superficial Tooth Enamel Journal of Dentistry. Apr, 2007 | Pubmed ID: 17116354 Measuring Carotid Artery Stenosis--comparison of Postmortem Arteriograms with the Planimetric Gold Standard Journal of Neurology. May, 2005 | Pubmed ID: 15778910 Effect of Mixing Technique on Shrinkage Rate of One Polyether and Two Polyvinyl Siloxane Impression Materials The International Journal of Prosthodontics. 2004 | Pubmed ID: 15543917 腫瘍スフェロイドモデルにおける抗体依存性細胞傷害性の定量化:創薬への応用 Isotta Sturniolo1,2, Csongor Váróczy1,3, Ákos Máté Bede1,3, Csaba Hegedűs1, Máté Á. Demény1,4, László Virág1,4 1Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 2Doctoral School of Molecular Medicine, University of Debrecen, 3National Academy of Scientist Education, 4HUN-REN-DE Cell Biology and Signaling Research Group JoVE 65922 Cancer Research 抗体依存性細胞傷害修飾化合物の同定のためのハイコンテントスクリーニングアッセイ(英語) Eliza Guti*1,2, Ákos Máté Bede*1,3, Csongor Váróczy*1,3, Csaba Hegedűs1, Máté Á. Demény1,4, László Virág1,4 1Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 2Doctoral School of Molecular Medicine, University of Debrecen, 3National Academy of Scientist Education, University of Debrecen, 4ELKH-DE Cell Biology and Signaling Research Group JoVE 64485 Cancer Research
腫瘍スフェロイドモデルにおける抗体依存性細胞傷害性の定量化:創薬への応用 Isotta Sturniolo1,2, Csongor Váróczy1,3, Ákos Máté Bede1,3, Csaba Hegedűs1, Máté Á. Demény1,4, László Virág1,4 1Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 2Doctoral School of Molecular Medicine, University of Debrecen, 3National Academy of Scientist Education, 4HUN-REN-DE Cell Biology and Signaling Research Group JoVE 65922 Cancer Research
抗体依存性細胞傷害修飾化合物の同定のためのハイコンテントスクリーニングアッセイ(英語) Eliza Guti*1,2, Ákos Máté Bede*1,3, Csongor Váróczy*1,3, Csaba Hegedűs1, Máté Á. Demény1,4, László Virág1,4 1Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 2Doctoral School of Molecular Medicine, University of Debrecen, 3National Academy of Scientist Education, University of Debrecen, 4ELKH-DE Cell Biology and Signaling Research Group JoVE 64485 Cancer Research
