Dan E. Berkowitz Department of Biomedical Engineering Johns Hopkins University Biography Publications Institution JoVE Articles Dan E. Berkowitz has not added a biography. If you are Dan E. Berkowitz and would like to personalize this page please email our Author Liaison for assistance. Publications Melanopsin Mediates Light-dependent Relaxation in Blood Vessels Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014 | Pubmed ID: 25404319 OxLDL Triggers Retrograde Translocation of Arginase2 in Aortic Endothelial Cells Via ROCK and Mitochondrial Processing Peptidase Circulation Research. Aug, 2014 | Pubmed ID: 24903103 Impaired Red Blood Cell Deformability After Transfusion of Stored Allogeneic Blood but Not Autologous Salvaged Blood in Cardiac Surgery Patients Anesthesia and Analgesia. Jun, 2014 | Pubmed ID: 24806142 Exercise, Vascular Stiffness, and Tissue Transglutaminase Journal of the American Heart Association. 2014 | Pubmed ID: 24721796 Effect of Isoflurane on Myocardial Energetic and Oxidative Stress in Cardiac Muscle from Zucker Diabetic Fatty Rat The Journal of Pharmacology and Experimental Therapeutics. Apr, 2014 | Pubmed ID: 24431470 New Insights Provided by a Comparison of Impaired Deformability with Erythrocyte Oxidative Stress for Sickle Cell Disease Blood Cells, Molecules & Diseases. Apr, 2014 | Pubmed ID: 24246527 Nitroprusside Inhibits Calcium-induced Impairment of Red Blood Cell Deformability Transfusion. Feb, 2014 | Pubmed ID: 23781865 Contribution of Arginase Activation to Vascular Dysfunction in Cigarette Smoking Atherosclerosis. Nov, 2013 | Pubmed ID: 24125417 Development of Novel Arginase Inhibitors for Therapy of Endothelial Dysfunction Frontiers in Immunology. 2013 | Pubmed ID: 24062745 Arginase II: Atherogenesis Beyond Enzyme Activity Journal of the American Heart Association. Aug, 2013 | Pubmed ID: 23938287 Increased Tissue Transglutaminase Activity Contributes to Central Vascular Stiffness in ENOS Knockout Mice American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2013 | Pubmed ID: 23873798 Sildenafil Citrate-restored ENOS and PDE5 Regulation in Sickle Cell Mouse Penis Prevents Priapism Via Control of Oxidative/nitrosative Stress PloS One. 2013 | Pubmed ID: 23844149 Sildenafil Citrate Protects Skeletal Muscle of Ischemia-reperfusion Injury: Immunohistochemical Study in Rat Model Acta Cirúrgica Brasileira / Sociedade Brasileira Para Desenvolvimento Pesquisa Em Cirurgia. Apr, 2013 | Pubmed ID: 23568236 Decreased Erythrocyte Deformability After Transfusion and the Effects of Erythrocyte Storage Duration Anesthesia and Analgesia. May, 2013 | Pubmed ID: 23449853 A Physiologic and Biochemical Profile of Clinically Rejected Lungs on a Normothermic Ex Vivo Lung Perfusion Platform The Journal of Surgical Research. Jul, 2013 | Pubmed ID: 23218735 Interleukin 10 Knockout Frail Mice Develop Cardiac and Vascular Dysfunction with Increased Age Experimental Gerontology. Feb, 2013 | Pubmed ID: 23159957 Nitric Oxide Regulates Tissue Transglutaminase Localization and Function in the Vasculature Amino Acids. Jan, 2013 | Pubmed ID: 21984378 Vasopressin-mediated Enhancement of Adrenergic Vasoconstriction Involves Both the Tyrosine Kinase and the Protein Kinase C Pathways Anesthesia and Analgesia. Dec, 2012 | Pubmed ID: 22886838 Increased Arginase II Activity Contributes to Endothelial Dysfunction Through Endothelial Nitric Oxide Synthase Uncoupling in Aged Mice Experimental & Molecular Medicine. Oct, 2012 | Pubmed ID: 22854495 Inhaled Hydrogen Sulfide Improves Graft Function in an Experimental Model of Lung Transplantation The Journal of Surgical Research. Jun, 2012 | Pubmed ID: 22771242 Alagebrium in Combination with Exercise Ameliorates Age-associated Ventricular and Vascular Stiffness Experimental Gerontology. Aug, 2012 | Pubmed ID: 22569357 Endothelial Nitric Oxide Synthase Mediates Cutaneous Vasodilation During Local Heating and is Attenuated in Middle-aged Human Skin Journal of Applied Physiology (Bethesda, Md. : 1985). Jun, 2012 | Pubmed ID: 22500004 Chronic Oral Administration of the Arginase Inhibitor 2(S)-amino-6-boronohexanoic Acid (ABH) Improves Erectile Function in Aged Rats Journal of Andrology. Nov-Dec, 2012 | Pubmed ID: 22492840 Hydrogen Sulfide Decreases Reactive Oxygen in a Model of Lung Transplantation The Journal of Surgical Research. Nov, 2012 | Pubmed ID: 22464394 Upregulation of Arginase-II Contributes to Decreased Age-related Myocardial Contractile Reserve European Journal of Applied Physiology. Aug, 2012 | Pubmed ID: 22160208 Nitric Oxide Regulates Non-classical Secretion of Tissue Transglutaminase Communicative & Integrative Biology. Sep, 2011 | Pubmed ID: 22046470 Hydrogen Sulfide As Endothelium-derived Hyperpolarizing Factor Sulfhydrates Potassium Channels Circulation Research. Nov, 2011 | Pubmed ID: 21980127 Upregulation of Inducible Nitric Oxide Synthase Contributes to Attenuated Cutaneous Vasodilation in Essential Hypertensive Humans Hypertension. Nov, 2011 | Pubmed ID: 21931069 Endothelial Arginase II and Atherosclerosis Korean Journal of Anesthesiology. Jul, 2011 | Pubmed ID: 21860744 Vascular Stiffness and Increased Pulse Pressure in the Aging Cardiovascular System Cardiology Research and Practice. 2011 | Pubmed ID: 21845218 HZE ⁵⁶Fe-ion Irradiation Induces Endothelial Dysfunction in Rat Aorta: Role of Xanthine Oxidase Radiation Research. Oct, 2011 | Pubmed ID: 21787183 S-nitrosation of Arginase 1 Requires Direct Interaction with Inducible Nitric Oxide Synthase Molecular and Cellular Biochemistry. Sep, 2011 | Pubmed ID: 21533769 Oral Atorvastatin Therapy Restores Cutaneous Microvascular Function by Decreasing Arginase Activity in Hypercholesterolaemic Humans The Journal of Physiology. Apr, 2011 | Pubmed ID: 21486801 Review Article: Implications of Vascular Aging Anesthesia and Analgesia. May, 2011 | Pubmed ID: 21474663 Phosphodiesterase-5A (PDE5A) is Localized to the Endothelial Caveolae and Modulates NOS3 Activity Cardiovascular Research. May, 2011 | Pubmed ID: 21421555 Restoring Leptin Signaling Reduces Hyperlipidemia and Improves Vascular Stiffness Induced by Chronic Intermittent Hypoxia American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2011 | Pubmed ID: 21278136 OxLDL-dependent Activation of Arginase II is Dependent on the LOX-1 Receptor and Downstream RhoA Signaling Atherosclerosis. Feb, 2011 | Pubmed ID: 21130456 Β 2-肾上腺素能受体耦合磷脂酰肌醇 3-激酶约束通过激活磷酸二酯酶 4 心脏假想的营地依赖增加。 Anesthesia and Analgesia. Oct, 2010 | Pubmed ID: 20705779 Increased Endothelial Exocytosis and Generation of Endothelin-1 Contributes to Constriction of Aged Arteries Circulation Research. Jul, 2010 | Pubmed ID: 20522806 Early Changes in Vasoreactivity After Simulated Microgravity Are Due to an Upregulation of the Endothelium-dependent Nitric Oxide/cGMP Pathway European Journal of Applied Physiology. Sep, 2010 | Pubmed ID: 20512503 Decreased S-nitrosylation of Tissue Transglutaminase Contributes to Age-related Increases in Vascular Stiffness Circulation Research. Jul, 2010 | Pubmed ID: 20489165 Single Exposure to Radiation Produces Early Anti-angiogenic Effects in Mouse Aorta Radiation and Environmental Biophysics. Aug, 2010 | Pubmed ID: 20401726 Dietary Inhibition of Xanthine Oxidase Attenuates Radiation-induced Endothelial Dysfunction in Rat Aorta Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2010 | Pubmed ID: 20167676 Arginase Inhibition Restores NOS Coupling and Reverses Endothelial Dysfunction and Vascular Stiffness in Old Rats Journal of Applied Physiology (Bethesda, Md. : 1985). Oct, 2009 | Pubmed ID: 19661445 Simulated Microgravity-induced Aortic Remodeling Journal of Applied Physiology (Bethesda, Md. : 1985). Jun, 2009 | Pubmed ID: 19299573 Sildenafil Inhibits Superoxide Formation and Prevents Endothelial Dysfunction in a Mouse Model of Secondhand Smoke Induced Erectile Dysfunction The Journal of Urology. Feb, 2009 | Pubmed ID: 19095260 Increased Oxidant Activity Mediates Vascular Dysfunction in Vibration Injury The Journal of Pharmacology and Experimental Therapeutics. Jan, 2009 | Pubmed ID: 18955588 Perioperative Blood Pressure Management: Does Central Vascular Stiffness Matter? Anesthesia and Analgesia. Oct, 2008 | Pubmed ID: 18806011 Arginase and Vascular Aging Journal of Applied Physiology (Bethesda, Md. : 1985). Nov, 2008 | Pubmed ID: 18719233 Selective Fluorescent Labeling of S-nitrosothiols (S-FLOS): a Novel Method for Studying S-nitrosation Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. Nov, 2008 | Pubmed ID: 18706513 Endothelial Arginase II: a Novel Target for the Treatment of Atherosclerosis Circulation Research. Apr, 2008 | Pubmed ID: 18309100 Mitochondrial Arginase II Constrains Endothelial NOS-3 Activity American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2007 | Pubmed ID: 17827260 Pulse Pressure is an Age-independent Predictor of Stroke Development After Cardiac Surgery Hypertension. Oct, 2007 | Pubmed ID: 17785628 Inducible NO Synthase Dependent S-nitrosylation and Activation of Arginase1 Contribute to Age-related Endothelial Dysfunction Circulation Research. Sep, 2007 | Pubmed ID: 17704205 Microgravity and Cardiac Atrophy: No Sex Discrimination Journal of Applied Physiology (Bethesda, Md. : 1985). Jul, 2007 | Pubmed ID: 17363626 Single Exposure Gamma-irradiation Amplifies Xanthine Oxidase Activity and Induces Endothelial Dysfunction in Rat Aorta Radiation and Environmental Biophysics. Jun, 2007 | Pubmed ID: 17256177 Myocyte Nitroso-redox Imbalance in Sepsis: NO Simple Answer Circulation Research. Jan, 2007 | Pubmed ID: 17204656 Microgravity-induced Changes in Aortic Stiffness and Their Role in Orthostatic Intolerance Journal of Applied Physiology (Bethesda, Md. : 1985). Mar, 2007 | Pubmed ID: 17082368 Impaired Shear Stress-induced Nitric Oxide Production Through Decreased NOS Phosphorylation Contributes to Age-related Vascular Stiffness Journal of Applied Physiology (Bethesda, Md. : 1985). Dec, 2006 | Pubmed ID: 17106067 Oxidized Low-density Lipoprotein-dependent Endothelial Arginase II Activation Contributes to Impaired Nitric Oxide Signaling Circulation Research. Oct, 2006 | Pubmed ID: 17008605 Activation of the Cardiac Ciliary Neurotrophic Factor Receptor Reverses Left Ventricular Hypertrophy in Leptin-deficient and Leptin-resistant Obesity Proceedings of the National Academy of Sciences of the United States of America. Mar, 2006 | Pubmed ID: 16537512 Arginase Modulates Myocardial Contractility by a Nitric Oxide Synthase 1-dependent Mechanism Proceedings of the National Academy of Sciences of the United States of America. Mar, 2006 | Pubmed ID: 16537391 Knockdown of Arginase I Restores NO Signaling in the Vasculature of Old Rats Hypertension. Feb, 2006 | Pubmed ID: 16380531 Cardiac Myocyte Apoptosis is Associated with Increased DNA Damage and Decreased Survival in Murine Models of Obesity Circulation Research. Jan, 2006 | Pubmed ID: 16339484 P66shc Regulates Endothelial NO Production and Endothelium-dependent Vasorelaxation: Implications for Age-associated Vascular Dysfunction Journal of Molecular and Cellular Cardiology. Dec, 2005 | Pubmed ID: 16242150 Simulated Microgravity Produces Attenuated Baroreflex-mediated Pressor, Chronotropic, and Inotropic Responses in Mice American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2005 | Pubmed ID: 15778286 Leptin Repletion Restores Depressed {beta}-adrenergic Contractility in Ob/ob Mice Independently of Cardiac Hypertrophy The Journal of Physiology. Jun, 2005 | Pubmed ID: 15760936 Neuronal Nitric Oxide Synthase Negatively Regulates Xanthine Oxidoreductase Inhibition of Cardiac Excitation-contraction Coupling Proceedings of the National Academy of Sciences of the United States of America. Nov, 2004 | Pubmed ID: 15486091 Apurinic/apyrimidinic Endonuclease 1 Regulates Endothelial NO Production and Vascular Tone Circulation Research. Oct, 2004 | Pubmed ID: 15472121 Critical Role for the Alpha-1B Adrenergic Receptor at the Sympathetic Neuroeffector Junction Hypertension. Nov, 2004 | Pubmed ID: 15466664 Enhanced Vasodilatory Responses to Milrinone in Catecholamine-precontracted Small Pulmonary Arteries Anesthesia and Analgesia. Jun, 2004 | Pubmed ID: 15155314 Arginase Reciprocally Regulates Nitric Oxide Synthase Activity and Contributes to Endothelial Dysfunction in Aging Blood Vessels Circulation. Oct, 2003 | Pubmed ID: 14517171 Disruption of Leptin Signaling Contributes to Cardiac Hypertrophy Independently of Body Weight in Mice Circulation. Aug, 2003 | Pubmed ID: 12885755 Nitric Oxide Regulation of Myocardial Contractility and Calcium Cycling: Independent Impact of Neuronal and Endothelial Nitric Oxide Synthases Circulation Research. Jun, 2003 | Pubmed ID: 12764022 Estrogen Has Opposing Effects on Vascular Reactivity in Obese, Insulin-resistant Male Zucker Rats Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2002 | Pubmed ID: 11960955 Nitric Oxide Regulates the Heart by Spatial Confinement of Nitric Oxide Synthase Isoforms Nature. Mar, 2002 | Pubmed ID: 11907582 Impaired Pulmonary Artery Contractile Responses in a Rat Model of Microgravity: Role of Nitric Oxide Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2002 | Pubmed ID: 11744640 测量升主动脉刚度 Maggie M. Kuo1, Viachaslau Barodka2, Theodore P. Abraham3, Jochen Steppan2, Artin A. Shoukas1, Mark Butlin4, Alberto Avolio4, Dan E. Berkowitz1,2, Lakshmi Santhanam1,2 1Department of Biomedical Engineering, Johns Hopkins University, 2Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, 3Department of Medicine (Cardiology), Johns Hopkins University, 4The Australian School of Advanced Medicine, Macquarie University Medicine
测量升主动脉刚度 Maggie M. Kuo1, Viachaslau Barodka2, Theodore P. Abraham3, Jochen Steppan2, Artin A. Shoukas1, Mark Butlin4, Alberto Avolio4, Dan E. Berkowitz1,2, Lakshmi Santhanam1,2 1Department of Biomedical Engineering, Johns Hopkins University, 2Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, 3Department of Medicine (Cardiology), Johns Hopkins University, 4The Australian School of Advanced Medicine, Macquarie University Medicine
