Lakshmi Santhanam Department of Biomedical Engineering Johns Hopkins University Biography Publications Institution JoVE Articles Lakshmi Santhanam has not added a biography. If you are Lakshmi Santhanam and would like to personalize this page please email our Author Liaison for assistance. Publications Melanopsin Mediates Light-dependent Relaxation in Blood Vessels Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014 | Pubmed ID: 25404319 Resveratrol Prevents High Fat/sucrose Diet-induced Central Arterial Wall Inflammation and Stiffening in Nonhuman Primates Cell Metabolism. Jul, 2014 | Pubmed ID: 24882067 Exercise, Vascular Stiffness, and Tissue Transglutaminase Journal of the American Heart Association. 2014 | Pubmed ID: 24721796 Nitroprusside Inhibits Calcium-induced Impairment of Red Blood Cell Deformability Transfusion. Feb, 2014 | Pubmed ID: 23781865 Contribution of Arginase Activation to Vascular Dysfunction in Cigarette Smoking Atherosclerosis. Nov, 2013 | Pubmed ID: 24125417 Arterial Stiffening Precedes Systolic Hypertension in Diet-induced Obesity Hypertension. Dec, 2013 | Pubmed ID: 24060894 Increased Tissue Transglutaminase Activity Contributes to Central Vascular Stiffness in ENOS Knockout Mice American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2013 | Pubmed ID: 23873798 Rho-Kinase Activity and Cutaneous Vasoconstriction is Upregulated in Essential Hypertensive Humans Microvascular Research. May, 2013 | Pubmed ID: 23481864 A Physiologic and Biochemical Profile of Clinically Rejected Lungs on a Normothermic Ex Vivo Lung Perfusion Platform The Journal of Surgical Research. Jul, 2013 | Pubmed ID: 23218735 Nitric Oxide Regulates Tissue Transglutaminase Localization and Function in the Vasculature Amino Acids. Jan, 2013 | Pubmed ID: 21984378 Inhaled Hydrogen Sulfide Improves Graft Function in an Experimental Model of Lung Transplantation The Journal of Surgical Research. Jun, 2012 | Pubmed ID: 22771242 Endothelial Nitric Oxide Synthase Mediates Cutaneous Vasodilation During Local Heating and is Attenuated in Middle-aged Human Skin Journal of Applied Physiology (Bethesda, Md. : 1985). Jun, 2012 | Pubmed ID: 22500004 Hydrogen Sulfide Decreases Reactive Oxygen in a Model of Lung Transplantation The Journal of Surgical Research. Nov, 2012 | Pubmed ID: 22464394 Upregulation of Arginase-II Contributes to Decreased Age-related Myocardial Contractile Reserve European Journal of Applied Physiology. Aug, 2012 | Pubmed ID: 22160208 Nitric Oxide Regulates Non-classical Secretion of Tissue Transglutaminase Communicative & Integrative Biology. Sep, 2011 | Pubmed ID: 22046470 Upregulation of Inducible Nitric Oxide Synthase Contributes to Attenuated Cutaneous Vasodilation in Essential Hypertensive Humans Hypertension. Nov, 2011 | Pubmed ID: 21931069 S-nitrosation of Arginase 1 Requires Direct Interaction with Inducible Nitric Oxide Synthase Molecular and Cellular Biochemistry. Sep, 2011 | Pubmed ID: 21533769 Oral Atorvastatin Therapy Restores Cutaneous Microvascular Function by Decreasing Arginase Activity in Hypercholesterolaemic Humans The Journal of Physiology. Apr, 2011 | Pubmed ID: 21486801 Decreased S-nitrosylation of Tissue Transglutaminase Contributes to Age-related Increases in Vascular Stiffness Circulation Research. Jul, 2010 | Pubmed ID: 20489165 Dietary Inhibition of Xanthine Oxidase Attenuates Radiation-induced Endothelial Dysfunction in Rat Aorta Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2010 | Pubmed ID: 20167676 Arginase Inhibition Restores NOS Coupling and Reverses Endothelial Dysfunction and Vascular Stiffness in Old Rats Journal of Applied Physiology (Bethesda, Md. : 1985). Oct, 2009 | Pubmed ID: 19661445 Cyclohexanone Contamination from Extracorporeal Circuits Impairs Cardiovascular Function American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2009 | Pubmed ID: 19411286 Arginase and Vascular Aging Journal of Applied Physiology (Bethesda, Md. : 1985). Nov, 2008 | Pubmed ID: 18719233 Selective Fluorescent Labeling of S-nitrosothiols (S-FLOS): a Novel Method for Studying S-nitrosation Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. Nov, 2008 | Pubmed ID: 18706513 Endothelial Arginase II: a Novel Target for the Treatment of Atherosclerosis Circulation Research. Apr, 2008 | Pubmed ID: 18309100 Inducible NO Synthase Dependent S-nitrosylation and Activation of Arginase1 Contribute to Age-related Endothelial Dysfunction Circulation Research. Sep, 2007 | Pubmed ID: 17704205 Single Exposure Gamma-irradiation Amplifies Xanthine Oxidase Activity and Induces Endothelial Dysfunction in Rat Aorta Radiation and Environmental Biophysics. Jun, 2007 | Pubmed ID: 17256177 Arginase Modulates Myocardial Contractility by a Nitric Oxide Synthase 1-dependent Mechanism Proceedings of the National Academy of Sciences of the United States of America. Mar, 2006 | Pubmed ID: 16537391 Sos-mediated Activation of Rac1 by P66shc The Journal of Cell Biology. Mar, 2006 | Pubmed ID: 16520382 Rac1 导致 P66shc 适配器蛋白质稳定性的磷酸化依赖增加： Rac1 诱导的氧化应激的作用。 Molecular Biology of the Cell. Jan, 2006 | Pubmed ID: 16251354 Structural Diversity of Peroxidase-catalyzed Oxidation Products of O-methoxyphenols Organic Letters. Jun, 2004 | Pubmed ID: 15176797 Inhibition of NADPH Oxidase Activation in Endothelial Cells by Ortho-methoxy-substituted Catechols Endothelium : Journal of Endothelial Cell Research. 2002 | Pubmed ID: 12380644 测量升主动脉刚度 Maggie M. Kuo1, Viachaslau Barodka2, Theodore P. Abraham3, Jochen Steppan2, Artin A. Shoukas1, Mark Butlin4, Alberto Avolio4, Dan E. Berkowitz1,2, Lakshmi Santhanam1,2 1Department of Biomedical Engineering, Johns Hopkins University, 2Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, 3Department of Medicine (Cardiology), Johns Hopkins University, 4The Australian School of Advanced Medicine, Macquarie University Medicine
测量升主动脉刚度 Maggie M. Kuo1, Viachaslau Barodka2, Theodore P. Abraham3, Jochen Steppan2, Artin A. Shoukas1, Mark Butlin4, Alberto Avolio4, Dan E. Berkowitz1,2, Lakshmi Santhanam1,2 1Department of Biomedical Engineering, Johns Hopkins University, 2Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, 3Department of Medicine (Cardiology), Johns Hopkins University, 4The Australian School of Advanced Medicine, Macquarie University Medicine
