David Kleinfeld Department of Physics University of California, San Diego Biography Publications Institution JoVE Articles David Kleinfeld has not added a biography. If you are David Kleinfeld and would like to personalize this page please email our Author Liaison for assistance. Publications The Brainstem Oscillator for Whisking and the Case for Breathing As the Master Clock for Orofacial Motor Actions Cold Spring Harbor Symposia on Quantitative Biology. Apr, 2015 | Pubmed ID: 25876629 Deflection of a Vibrissa Leads to a Gradient of Strain Across Mechanoreceptors in a Mystacial Follicle Journal of Neurophysiology. Apr, 2015 | Pubmed ID: 25855692 Fluorescently Labeled Peptide Increases Identification of Degenerated Facial Nerve Branches During Surgery and Improves Functional Outcome PloS One. 2015 | Pubmed ID: 25751149 Robust and Fragile Aspects of Cortical Blood Flow in Relation to the Underlying Angioarchitecture Microcirculation (New York, N.Y. : 1994). Apr, 2015 | Pubmed ID: 25705966 Feedback in the Brainstem: an Excitatory Disynaptic Pathway for Control of Whisking The Journal of Comparative Neurology. Apr, 2015 | Pubmed ID: 25503925 Muscles Involved in Naris Dilation and Nose Motion in Rat Anatomical Record (Hoboken, N.J. : 2007). Mar, 2015 | Pubmed ID: 25257748 The Musculature That Drives Active Touch by Vibrissae and Nose in Mice Anatomical Record (Hoboken, N.J. : 2007). Nov, 2014 | Pubmed ID: 25408106 Cell-based Reporters Reveal in Vivo Dynamics of Dopamine and Norepinephrine Release in Murine Cortex Nature Methods. Dec, 2014 | Pubmed ID: 25344639 Activation and Measurement of Free Whisking in the Lightly Anesthetized Rodent Nature Protocols. Aug, 2014 | Pubmed ID: 24992095 How the Brainstem Controls Orofacial Behaviors Comprised of Rhythmic Actions Trends in Neurosciences. Jul, 2014 | Pubmed ID: 24890196 More Than a Rhythm of Life: Breathing As a Binder of Orofacial Sensation Nature Neuroscience. May, 2014 | Pubmed ID: 24762718 Spectral Methods for Functional Brain Imaging Cold Spring Harbor Protocols. Mar, 2014 | Pubmed ID: 24591695 Optically Induced Occlusion of Single Blood Vessels in Rodent Neocortex Cold Spring Harbor Protocols. Dec, 2013 | Pubmed ID: 24298038 Mediation of Muscular Control of Rhinarial Motility in Rats by the Nasal Cartilaginous Skeleton Anatomical Record (Hoboken, N.J. : 2007). Dec, 2013 | Pubmed ID: 24249396 The Challenge of Connecting the Dots in the B.R.a.I.N Neuron. Oct, 2013 | Pubmed ID: 24139032 All-optical Osteotomy to Create Windows for Transcranial Imaging in Mice Optics Express. Oct, 2013 | Pubmed ID: 24104230 ReaChR: a Red-shifted Variant of Channelrhodopsin Enables Deep Transcranial Optogenetic Excitation Nature Neuroscience. Oct, 2013 | Pubmed ID: 23995068 Two-photon Imaging of Blood Flow in the Rat Cortex Cold Spring Harbor Protocols. Aug, 2013 | Pubmed ID: 23906919 The Cortical Angiome: an Interconnected Vascular Network with Noncolumnar Patterns of Blood Flow Nature Neuroscience. Jul, 2013 | Pubmed ID: 23749145 Hierarchy of Orofacial Rhythms Revealed Through Whisking and Breathing Nature. May, 2013 | Pubmed ID: 23624373 All-optical in Situ Histology of Brain Tissue with Femtosecond Laser Pulses Cold Spring Harbor Protocols. Apr, 2013 | Pubmed ID: 23547156 The Smallest Stroke: Occlusion of One Penetrating Vessel Leads to Infarction and a Cognitive Deficit Nature Neuroscience. Jan, 2013 | Pubmed ID: 23242312 Vectorization of Optically Sectioned Brain Microvasculature: Learning Aids Completion of Vascular Graphs by Connecting Gaps and Deleting Open-ended Segments Medical Image Analysis. Aug, 2012 | Pubmed ID: 22854035 Dorsorostral Snout Muscles in the Rat Subserve Coordinated Movement for Whisking and Sniffing Anatomical Record (Hoboken, N.J. : 2007). Jul, 2012 | Pubmed ID: 22641389 动作电位的干涉检测。 Cold Spring Harbor Protocols. 2012 | Pubmed ID: 22383643 作为一种工具来研究血液流动和耦合在鼠脑中的神经血管的双光子显微镜。 Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2012 | Pubmed ID: 22293983 展望反馈指导用超短脉冲的激光手术。 Current Opinion in Neurobiology. Feb, 2012 | Pubmed ID: 22088392 探查和搅拌在啮齿类动物。 Current Opinion in Neurobiology. Dec, 2011 | Pubmed ID: 22177596 触须扫描感觉运动系统中的对象位置的神经基础。 Neuron. Nov, 2011 | Pubmed ID: 22078505 大型自动化的组织学的 Connectomes 的追求。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2011 | Pubmed ID: 22072665 运动皮层报告传出的触须运动控制多个时间尺度。 Neuron. Oct, 2011 | Pubmed ID: 22017992 质量度量标准来陪峰值的胞外信号进行排序。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2011 | Pubmed ID: 21677152 一本指南,划定的信号在大脑中的神经血管的逻辑。 Frontiers in Neuroenergetics. 2011 | Pubmed ID: 21559095 啮齿动物皮质的波动和感官诱导 Vasodynamics 延长小动脉的能力。 Proceedings of the National Academy of Sciences of the United States of America. May, 2011 | Pubmed ID: 21536897 光子计数、 检查员更正和寿命改进检测的双光子显微镜成像。 Journal of Neurophysiology. Jun, 2011 | Pubmed ID: 21471395 表征与基因编码 Ca2 + + 传感器配体门控离子通道受体。 PloS One. 2011 | Pubmed ID: 21305050 时空暂时集中 Nonreciprocal 光学透明材料写作的飞秒激光脉冲。 Optics Express. Nov, 2010 | Pubmed ID: 21164813 通过抛光和钢筋稀疏颅骨慢性光纤接入。 Nature Methods. Dec, 2010 | Pubmed ID: 20966916 暂时集中通过光学透明材料低数值孔径微细加工的飞秒激光脉冲。 Optics Express. Aug, 2010 | Pubmed ID: 20721196 对鼠大脑皮层血液的鲁棒分布的拓扑基础。 Proceedings of the National Academy of Sciences of the United States of America. Jul, 2010 | Pubmed ID: 20616030 遗传物质标记的脑细胞快速功能成像的自动识别。 Journal of Neurophysiology. Sep, 2010 | Pubmed ID: 20610792 优化双光子激光扫描显微镜与色散补偿的收益,荧光。 Optics Express. Jun, 2010 | Pubmed ID: 20588500 神经递质释放和原位受体活性的体内生物传感器。 Nature Neuroscience. Jan, 2010 | Pubmed ID: 20010818 从时空图像使用氡变换的粒子速度的快速测定。 Journal of Computational Neuroscience. Aug, 2010 | Pubmed ID: 19459038 揭示的直接计数和原子核和船只的共定位的小鼠皮质神经元和微血管密度的相关性。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2009 | Pubmed ID: 19923289 输入 Ratrix。 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2009 | Pubmed ID: 19906991 严重血脑屏障的破坏和周围软组织损伤。 Stroke; a Journal of Cerebral Circulation. Dec, 2009 | Pubmed ID: 19893002 神经胶质细胞反应的是低氧诱导小鼠红细胞生成的重要组成部分。 The Journal of Clinical Investigation. Nov, 2009 | Pubmed ID: 19809162 急性血管中断和脑卒中后的水通道蛋白 4 损失。 Stroke; a Journal of Cerebral Circulation. Jun, 2009 | Pubmed ID: 19372455 Brainwide 解剖结构连接的介观尺度模式生物测定协调努力的建议。 PLoS Computational Biology. Mar, 2009 | Pubmed ID: 19325892 相位到率转换编码扫描的感觉运动系统的皮层神经元的触摸。 Nature Neuroscience. Apr, 2009 | Pubmed ID: 19270688 介导等离子消融: 亚微米级手术对神经和血管系统的光学工具。 Current Opinion in Biotechnology. Feb, 2009 | Pubmed ID: 19269159 积极扩张的穿透小动脉局灶性脑卒中后将红细胞血流量恢复到半影大脑皮层。 Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Apr, 2009 | Pubmed ID: 19174826 刺激引起的变化,在血流量和 2-脱氧葡萄糖吸收游离在同侧躯体感觉皮层。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2008 | Pubmed ID: 19118167 第 10 章。体内测量血流量和神经胶质细胞功能与双光子激光扫描显微镜。 Methods in Enzymology. 2008 | Pubmed ID: 19007667 推进多焦非线性显微镜: 发展和应用的新型多波束 Yb:KGd (WO4) 2 振荡器。 Optics Express. Oct, 2008 | Pubmed ID: 18958037 纹理在大鼠晶须系统编码: 滑与微分共振。 PLoS Biology. Aug, 2008 | Pubmed ID: 18752354 在自发振荡中查找的一致性。 Nature Neuroscience. Sep, 2008 | Pubmed ID: 18725901 位置和什么晶感觉系统中。 Nature Reviews. Neuroscience. Aug, 2008 | Pubmed ID: 18641667 生物力学研究大鼠的触须电机厂: 节奏搅拌的胃壁神经肌肉活动组成。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2008 | Pubmed ID: 18367610 疯狂彭菲尔德时代的 YouTube: 可视化的感觉运动领域的顺序激活整个大脑皮层。 Neuron. Dec, 2007 | Pubmed ID: 18054853 抑制性神经元活动和并发动脉血管收缩可能解释负值血液氧合水平依赖的信号。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2007 | Pubmed ID: 17442830 大型双光子 Absorptivity 的血红蛋白在 780-880 Nm 红外范围内。 The Journal of Chemical Physics. Jan, 2007 | Pubmed ID: 17228976 在扫描感觉运动系统的触须的活动空间感知。 PLoS Biology. Feb, 2007 | Pubmed ID: 17227143 有共同的起源,环绕抑制与血流动力学变化的电活动通过看到吗?在"持续时间依赖响应硅中松鼠猴 Vibrotactile 刺激"的重点。 Journal of Neurophysiology. Mar, 2007 | Pubmed ID: 17215499 穿透小动脉灌注的大脑皮层中的一个瓶颈。 Proceedings of the National Academy of Sciences of the United States of America. Jan, 2007 | Pubmed ID: 17190804 积极的感觉: 从啮齿动物的触须感觉运动系统的见解。 Current Opinion in Neurobiology. Aug, 2006 | Pubmed ID: 16837190 探索性搅拌的大鼠不是锁定的海马 Theta 节奏的阶段。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2006 | Pubmed ID: 16775139 看到鼠标同其触须毛看到什么: 行为状态的问题。 Neuron. May, 2006 | Pubmed ID: 16701202 MPScope: 用于多光子显微镜多功能软件套件。 Journal of Neuroscience Methods. Sep, 2006 | Pubmed ID: 16621010 有针对性的对地下皮质血管用超短激光脉冲的侮辱: 脑卒中的三种模式。 Nature Methods. Feb, 2006 | Pubmed ID: 16432519 科学是一次冒险,不是一场战斗。 Nature. Jan, 2006 | Pubmed ID: 16397477 双光子成像的皮质表面微血管揭示了鲁棒重新分配在血流后血管闭塞。 PLoS Biology. Feb, 2006 | Pubmed ID: 16379497 编码的刺激频率由丘脑 GABAB 介导的反馈和刺激形状之间的相互作用通过网络中的延迟。 Journal of Neurophysiology. Mar, 2006 | Pubmed ID: 16267113 从艺术到工程?通过为基因标记和非线性成像的哺乳动物体内生理兴起。 PLoS Biology. Oct, 2005 | Pubmed ID: 16207078 激活核尺蛾便利皮质脑干电机程序控制。 Journal of Neurophysiology. Jul, 2005 | Pubmed ID: 15728764 在脑干触觉感觉运动循环中的积极反馈。 Neuron. Feb, 2005 | Pubmed ID: 15694330 当前流的触须运动皮层可以锁相与大鼠探索性节奏搅拌。 Journal of Neurophysiology. Sep, 2004 | Pubmed ID: 15331651 目标导向搅拌增加阶段锁定触须运动与大鼠初级感觉皮层电活动。 Proceedings of the National Academy of Sciences of the United States of America. Aug, 2004 | Pubmed ID: 15297618 发育调控的主动和被动的膜在大鼠触须 Motoneurones 属性。 The Journal of Physiology. Apr, 2004 | Pubmed ID: 14766934 跳来跳去胡须: 图案感官输入在大鼠触须系统。 Neuron. Jan, 2004 | Pubmed ID: 14741099 成像显示游泳终止在 CNS 水蛭神经元突触的目标。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2003 | Pubmed ID: 14673004 扭转小脑的长期萧条。 Proceedings of the National Academy of Sciences of the United States of America. Dec, 2003 | Pubmed ID: 14671315 触须运动诱发节奏电微刺激对运动皮层中探索性引起的大鼠模拟搅拌。 Journal of Neurophysiology. Nov, 2003 | Pubmed ID: 12904336 单方面的触须联系人: 振幅但不是计时的节奏搅拌的变化。 Somatosensory & Motor Research. 2003 | Pubmed ID: 12850826 全光组织学用超短激光脉冲。 Neuron. Jul, 2003 | Pubmed ID: 12848930 大鼠的节奏搅拌: 退缩,以及前方的触须毛是主动肌肉控制下。 Journal of Neurophysiology. Jan, 2003 | Pubmed ID: 12522163 闭环神经元计算: 侧重于大鼠触须 Somatosensation。 Cerebral Cortex (New York, N.Y. : 1991). Jan, 2003 | Pubmed ID: 12466215 光谱混合的节奏感觉皮层的神经元信号。 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2002 | Pubmed ID: 12403828 自适应滤波的触须的大鼠运动皮层中的投入。 Neuron. Jun, 2002 | Pubmed ID: 12086648 触须感官领域的小脑和大脑皮层之间的连贯电活动被增强期间免费搅拌。 Journal of Neurophysiology. Apr, 2002 | Pubmed ID: 11929931 通过使用双光子激光扫描显微镜的头骨完好无损鼠标的皮质成像。 Microscopy Research and Technique. Feb, 2002 | Pubmed ID: 11877806 构建基于细胞的神经递质荧光工程记者(CNiFERs)神经递质的光学检测 Emre Lacin1, Arnaud Muller2, Marian Fernando1, David Kleinfeld2,3, Paul A. Slesinger1 1Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 2Department of Physics, University of California, San Diego, 3Section of Neurobiology, University of California, San Diego JoVE 53290 Neuroscience 警报,头抑制大鼠子皮层的大脑结构中Juxtacellular监测和本地化单神经元 Jeffrey D. Moore1, Martin Deschênes2, David Kleinfeld1 1Department of Physics 0374, University of California, San Diego, 2Department of Psychiatry and Neuroscience, Centre de Recherche de l’Université Laval Robert-Giffard Neuroscience 抛光和钢筋,颅骨变薄窗口,为长期的小鼠脑成像 Andy Y. Shih1, Celine Mateo1, Patrick J. Drew2,3, Philbert S. Tsai1, David Kleinfeld1,4 1Department of Physics, University of California, San Diego, 2Department of Engineering Science and Mechanics, Pennsylvania State University, 3Department of Neurosurgery, Pennsylvania State University, 4Section of Neurobiology, University of California, San Diego JoVE 3742 Neuroscience
构建基于细胞的神经递质荧光工程记者(CNiFERs)神经递质的光学检测 Emre Lacin1, Arnaud Muller2, Marian Fernando1, David Kleinfeld2,3, Paul A. Slesinger1 1Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 2Department of Physics, University of California, San Diego, 3Section of Neurobiology, University of California, San Diego JoVE 53290 Neuroscience
警报,头抑制大鼠子皮层的大脑结构中Juxtacellular监测和本地化单神经元 Jeffrey D. Moore1, Martin Deschênes2, David Kleinfeld1 1Department of Physics 0374, University of California, San Diego, 2Department of Psychiatry and Neuroscience, Centre de Recherche de l’Université Laval Robert-Giffard Neuroscience
抛光和钢筋,颅骨变薄窗口,为长期的小鼠脑成像 Andy Y. Shih1, Celine Mateo1, Patrick J. Drew2,3, Philbert S. Tsai1, David Kleinfeld1,4 1Department of Physics, University of California, San Diego, 2Department of Engineering Science and Mechanics, Pennsylvania State University, 3Department of Neurosurgery, Pennsylvania State University, 4Section of Neurobiology, University of California, San Diego JoVE 3742 Neuroscience