Denis Wirtz Department of Chemical and Biomolecular Engineering Johns Hopkins University Biography Publications Institution JoVE Articles Denis Wirtz has not added a biography. If you are Denis Wirtz and would like to personalize this page please email our Author Liaison for assistance. Publications EB1 and Cytoplasmic Dynein Mediate Protrusion Dynamics for Efficient 3-dimensional Cell Migration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2017 | Pubmed ID: 29097501 Loss of Giant Obscurins Alters Breast Epithelial Cell Mechanosensing of Matrix Stiffness Oncotarget. Aug, 2017 | Pubmed ID: 28903319 Pluri-IQ: Quantification of Embryonic Stem Cell Pluripotency Through An Image-Based Analysis Software Stem Cell Reports. Aug, 2017 | Pubmed ID: 28712847 Synergistic IL-6 and IL-8 Paracrine Signalling Pathway Infers a Strategy to Inhibit Tumour Cell Migration Nature Communications. May, 2017 | Pubmed ID: 28548090 Affine and Non-affine Deformations Quantified in Cytoskeletal Networks Through Three-dimensional Form-finding Model Journal of the Mechanical Behavior of Biomedical Materials. Aug, 2017 | Pubmed ID: 28448922 Hypoxia Selectively Enhances Integrin α5β1 Receptor Expression in Breast Cancer to Promote Metastasis Molecular Cancer Research : MCR. Jun, 2017 | Pubmed ID: 28213554 Modeling the Two-way Feedback Between Contractility and Matrix Realignment Reveals a Nonlinear Mode of Cancer Cell Invasion Proceedings of the National Academy of Sciences of the United States of America. Feb, 2017 | Pubmed ID: 28196892 Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes Neuron. Feb, 2017 | Pubmed ID: 28132831 Engineered Models of Confined Cell Migration Annual Review of Biomedical Engineering. Jul, 2016 | Pubmed ID: 27420571 Confinement Sensing and Signal Optimization Via Piezo1/PKA and Myosin II Pathways Cell Reports. 05, 2016 | Pubmed ID: 27160899 Biophysical Changes Reduce Energetic Demand in Growth Factor-deprived Lymphocytes The Journal of Cell Biology. Feb, 2016 | Pubmed ID: 26880201 Differential Vesicular Sorting of AMPA and GABAA Receptors Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26839408 A Robust Nonlinear Tissue-component Discrimination Method for Computational Pathology Laboratory Investigation; a Journal of Technical Methods and Pathology. Apr, 2016 | Pubmed ID: 26779829 Local 3D Matrix Confinement Determines Division Axis Through Cell Shape Oncotarget. Feb, 2016 | Pubmed ID: 26515603 Evolution of Cellular Morpho-phenotypes in Cancer Metastasis Scientific Reports. Dec, 2015 | Pubmed ID: 26675084 The Mechanobiology of Aging Annual Review of Biomedical Engineering. 2015 | Pubmed ID: 26643020 Collective Cancer Cell Invasion Induced by Coordinated Contractile Stresses Oncotarget. Dec, 2015 | Pubmed ID: 26528856 Senescent Stromal Cells Induce Cancer Cell Migration Via Inhibition of RhoA/ROCK/myosin-based Cell Contractility Oncotarget. Oct, 2015 | Pubmed ID: 26483365 Three-dimensional Matrix Fiber Alignment Modulates Cell Migration and MT1-MMP Utility by Spatially and Temporally Directing Protrusions Scientific Reports. Oct, 2015 | Pubmed ID: 26423227 Normal Mammary Epithelial Cells Promote Carcinoma Basement Membrane Invasion by Inducing Microtubule-rich Protrusions Oncotarget. Oct, 2015 | Pubmed ID: 26334095 Distinct Kinetic and Mechanical Properties Govern Mucin 16- and Podocalyxin-mediated Tumor Cell Adhesion to E- and L-selectin in Shear Flow Oncotarget. Sep, 2015 | Pubmed ID: 26329844 Volume Regulation and Shape Bifurcation in the Cell Nucleus Journal of Cell Science. Sep, 2015 | Pubmed ID: 26243474 Multiple Scale Model for Cell Migration in Monolayers: Elastic Mismatch Between Cells Enhances Motility Scientific Reports. Jul, 2015 | Pubmed ID: 26134134 Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules Cancer Cell. Jul, 2015 | Pubmed ID: 26096845 Statistical Analysis of Cell Migration in 3D Using the Anisotropic Persistent Random Walk Model Nature Protocols. Mar, 2015 | Pubmed ID: 25719270 COX-2 Dependent Regulation of Mechanotransduction in Human Breast Cancer Cells Cancer Biology & Therapy. 2015 | Pubmed ID: 25701047 Cytoskeletal Tension Induces the Polarized Architecture of the Nucleus Biomaterials. Apr, 2015 | Pubmed ID: 25701041 Switching from Protease-independent to Protease-dependent Cancer Cell Invasion Biophysical Journal. Dec, 2014 | Pubmed ID: 25468324 Hypoxia and the Extracellular Matrix: Drivers of Tumour Metastasis Nature Reviews. Cancer. 06, 2014 | Pubmed ID: 24827502 Water Permeation Drives Tumor Cell Migration in Confined Microenvironments Cell. Apr, 2014 | Pubmed ID: 24726433 Local Mechanical Response of Cells to the Controlled Rotation of Magnetic Nanorods Journal of Biomedical Materials Research. Part B, Applied Biomaterials. Nov, 2014 | Pubmed ID: 24700696 Tight Coupling Between Nucleus and Cell Migration Through the Perinuclear Actin Cap Journal of Cell Science. Jun, 2014 | Pubmed ID: 24639463 Three-dimensional Cell Migration Does Not Follow a Random Walk Proceedings of the National Academy of Sciences of the United States of America. Mar, 2014 | Pubmed ID: 24594603 Nuclear Envelope in Nuclear Positioning and Cell Migration Advances in Experimental Medicine and Biology. 2014 | Pubmed ID: 24563361 Hypoxia-inducible Factors Mediate Coordinated RhoA-ROCK1 Expression and Signaling in Breast Cancer Cells Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014 | Pubmed ID: 24324133 Morphological Effects on Expression of Growth Differentiation Factor 15 (GDF15), a Marker of Metastasis Journal of Cellular Physiology. Mar, 2014 | Pubmed ID: 23996089 β-Catenin Serves As a Clutch Between Low and High Intercellular E-cadherin Bond Strengths Biophysical Journal. Nov, 2013 | Pubmed ID: 24268141 Form-finding Model Shows How Cytoskeleton Network Stiffness is Realized PloS One. 2013 | Pubmed ID: 24146992 Adhesion and Fusion Efficiencies of Human Immunodeficiency Virus Type 1 (HIV-1) Surface Proteins Scientific Reports. 2013 | Pubmed ID: 24145278 Modulation of Keratocyte Phenotype by Collagen Fibril Nanoarchitecture in Membranes for Corneal Repair Biomaterials. Dec, 2013 | Pubmed ID: 24041426 The Multi-faceted Role of the Actin Cap in Cellular Mechanosensation and Mechanotransduction Soft Matter. Jun, 2013 | Pubmed ID: 23930135 The Arp2/3 Complex Mediates Multigeneration Dendritic Protrusions for Efficient 3-dimensional Cancer Cell Migration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2013 | Pubmed ID: 23796785 Age-dependent Stochastic Models for Understanding Population Fluctuations in Continuously Cultured Cells Journal of the Royal Society, Interface. Aug, 2013 | Pubmed ID: 23760298 Predicting How Cells Spread and Migrate: Focal Adhesion Size Does Matter Cell Adhesion & Migration. May-Jun, 2013 | Pubmed ID: 23628962 Collagen Prolyl Hydroxylases Are Essential for Breast Cancer Metastasis Cancer Research. Jun, 2013 | Pubmed ID: 23539444 Simultaneously Defining Cell Phenotypes, Cell Cycle, and Chromatin Modifications at Single-cell Resolution FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2013 | Pubmed ID: 23538711 Interstitial Friction Greatly Impacts Membrane Mechanics Biophysical Journal. Mar, 2013 | Pubmed ID: 23528079 Dimensional Control of Cancer Cell Migration Biophysical Journal. Jan, 2013 | Pubmed ID: 23442847 Hypoxia-inducible Factor 1 (HIF-1) Promotes Extracellular Matrix Remodeling Under Hypoxic Conditions by Inducing P4HA1, P4HA2, and PLOD2 Expression in Fibroblasts The Journal of Biological Chemistry. Apr, 2013 | Pubmed ID: 23423382 Procollagen Lysyl Hydroxylase 2 is Essential for Hypoxia-induced Breast Cancer Metastasis Molecular Cancer Research : MCR. May, 2013 | Pubmed ID: 23378577 High-throughput Secretomic Analysis of Single Cells to Assess Functional Cellular Heterogeneity Analytical Chemistry. Feb, 2013 | Pubmed ID: 23339603 The LINC-anchored Actin Cap Connects the Extracellular Milieu to the Nucleus for Ultrafast Mechanotransduction Scientific Reports. 2013 | Pubmed ID: 23336069 Functional Interplay Between the Cell Cycle and Cell Phenotypes Integrative Biology : Quantitative Biosciences from Nano to Macro. Mar, 2013 | Pubmed ID: 23319145 Focal Adhesion Size Uniquely Predicts Cell Migration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2013 | Pubmed ID: 23254340 Effect of Modifying Quantum Dot Surface Charge on Airway Epithelial Cell Uptake in Vitro Nanotoxicology. Sep, 2013 | Pubmed ID: 22783847 Distinct Kinetic and Molecular Requirements Govern CD44 Binding to Hyaluronan Versus Fibrin(ogen) Biophysical Journal. Aug, 2012 | Pubmed ID: 22947857 Actin Cap Associated Focal Adhesions and Their Distinct Role in Cellular Mechanosensing Scientific Reports. 2012 | Pubmed ID: 22870384 The Distinct Roles of the Nucleus and Nucleus-cytoskeleton Connections in Three-dimensional Cell Migration Scientific Reports. 2012 | Pubmed ID: 22761994 NAC1 is an Actin-binding Protein That is Essential for Effective Cytokinesis in Cancer Cells Cancer Research. Aug, 2012 | Pubmed ID: 22761335 Mismatch in Mechanical and Adhesive Properties Induces Pulsating Cancer Cell Migration in Epithelial Monolayer Biophysical Journal. Jun, 2012 | Pubmed ID: 22735523 The Differential Formation of the LINC-mediated Perinuclear Actin Cap in Pluripotent and Somatic Cells PloS One. 2012 | Pubmed ID: 22574215 Divergent Roles of CD44 and Carcinoembryonic Antigen in Colon Cancer Metastasis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2012 | Pubmed ID: 22415308 Dimensional and Temporal Controls of Three-dimensional Cell Migration by Zyxin and Binding Partners Nature Communications. Mar, 2012 | Pubmed ID: 22395610 High-throughput Ballistic Injection Nanorheology to Measure Cell Mechanics Nature Protocols. Jan, 2012 | Pubmed ID: 22222790 Nucleation and Decay Initiation Are the Stiffness-sensitive Phases of Focal Adhesion Maturation Biophysical Journal. Dec, 2011 | Pubmed ID: 22208190 SMRT Analysis of MTOC and Nuclear Positioning Reveals the Role of EB1 and LIC1 in Single-cell Polarization Journal of Cell Science. Dec, 2011 | Pubmed ID: 22193958 Magnetic Manipulation of Nanorods in the Nucleus of Living Cells Biophysical Journal. Oct, 2011 | Pubmed ID: 22004741 Hypoxia-inducible Factor 1 is a Master Regulator of Breast Cancer Metastatic Niche Formation Proceedings of the National Academy of Sciences of the United States of America. Sep, 2011 | Pubmed ID: 21911388 The Physics of Cancer: the Role of Physical Interactions and Mechanical Forces in Metastasis Nature Reviews. Cancer. Jun, 2011 | Pubmed ID: 21701513 Single-molecule Binding of CD44 to Fibrin Versus P-selectin Predicts Their Distinct Shear-dependent Interactions in Cancer Journal of Cell Science. Jun, 2011 | Pubmed ID: 21558419 Recapitulating Cancer Cell Invasion in Vitro Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21490296 Biophysics of Selectin-ligand Interactions in Inflammation and Cancer Physical Biology. Feb, 2011 | Pubmed ID: 21301059 The Perinuclear Actin Cap in Health and Disease Nucleus (Austin, Tex.). Jul-Aug, 2010 | Pubmed ID: 21327082 Differences in the Microrheology of Human Embryonic Stem Cells and Human Induced Pluripotent Stem Cells Biophysical Journal. Dec, 2010 | Pubmed ID: 21112280 Interplay of RhoA and Motility in the Programmed Spreading of Daughter Cells Postmitosis Biophysical Journal. Dec, 2010 | Pubmed ID: 21112276 Torsional Mechanics of DNA Are Regulated by Small-molecule Intercalation The Journal of Physical Chemistry. B. Dec, 2010 | Pubmed ID: 21090816 Cross-linking FtsZ Polymers into Coherent Z Rings Molecular Microbiology. Nov, 2010 | Pubmed ID: 20969647 PEG-based Hydrogels with Collagen Mimetic Peptide-mediated and Tunable Physical Cross-links Biomacromolecules. Sep, 2010 | Pubmed ID: 20715762 Organization of Cellular Receptors into a Nanoscale Junction During HIV-1 Adhesion PLoS Computational Biology. Jul, 2010 | Pubmed ID: 20657663 MEX-5 Enrichment in the C. Elegans Early Embryo Mediated by Differential Diffusion Development (Cambridge, England). Aug, 2010 | Pubmed ID: 20627961 Triggering Cell Detachment from Patterned Electrode Arrays by Programmed Subcellular Release Nature Protocols. Jul, 2010 | Pubmed ID: 20595956 A Distinctive Role for Focal Adhesion Proteins in Three-dimensional Cell Motility Nature Cell Biology. Jun, 2010 | Pubmed ID: 20473295 Dynamics of the Bacterial Intermediate Filament Crescentin in Vitro and in Vivo PloS One. Jan, 2010 | Pubmed ID: 20140233 A Perinuclear Actin Cap Regulates Nuclear Shape Proceedings of the National Academy of Sciences of the United States of America. Nov, 2009 | Pubmed ID: 19850871 Resolving the Role of Actoymyosin Contractility in Cell Microrheology PloS One. Sep, 2009 | Pubmed ID: 19756147 Loss of Alpha-catenin Decreases the Strength of Single E-cadherin Bonds Between Human Cancer Cells The Journal of Biological Chemistry. Jul, 2009 | Pubmed ID: 19458087 Particle-tracking Microrheology of Living Cells: Principles and Applications Annual Review of Biophysics. 2009 | Pubmed ID: 19416071 Magnetic Tweezers Measurement of Single Molecule Torque Nano Letters. Apr, 2009 | Pubmed ID: 19301859 Asymmetric Enrichment of PIE-1 in the Caenorhabditis Elegans Zygote Mediated by Binary Counterdiffusion The Journal of Cell Biology. Feb, 2009 | Pubmed ID: 19221192 Alpha-actinin and Filamin Cooperatively Enhance the Stiffness of Actin Filament Networks PloS One. 2009 | Pubmed ID: 19198659 Programmed Subcellular Release for Studying the Dynamics of Cell Detachment Nature Methods. Mar, 2009 | Pubmed ID: 19182793 Altering Mucus Rheology to "solidify" Human Mucus at the Nanoscale PloS One. 2009 | Pubmed ID: 19173002 Micro- and Macrorheology of Mucus Advanced Drug Delivery Reviews. Feb, 2009 | Pubmed ID: 19166889 Condensation of FtsZ Filaments Can Drive Bacterial Cell Division Proceedings of the National Academy of Sciences of the United States of America. Jan, 2009 | Pubmed ID: 19116281 Chapter 18: Sensing Cytoskeletal Mechanics by Ballistic Intracellular Nanorheology (BIN) Coupled with Cell Transfection Methods in Cell Biology. 2008 | Pubmed ID: 19118687 Chapter 15: Live-cell Single-molecule Force Spectroscopy Methods in Cell Biology. 2008 | Pubmed ID: 19118684 {alpha}-Catenin Mediates Initial E-cadherin-dependent Cell-cell Recognition and Subsequent Bond Strengthening Proceedings of the National Academy of Sciences of the United States of America. Nov, 2008 | Pubmed ID: 19017792 The Filamentous Actin Cross-linking/bundling Activity of Mammalian Formins Journal of Molecular Biology. Dec, 2008 | Pubmed ID: 18835565 Dysfunctional Connections Between the Nucleus and the Actin and Microtubule Networks in Laminopathic Models Biophysical Journal. Dec, 2008 | Pubmed ID: 18790843 Mapping Local Matrix Remodeling Induced by a Migrating Tumor Cell Using Three-dimensional Multiple-particle Tracking Biophysical Journal. Oct, 2008 | Pubmed ID: 18641063 Polymerization and Bundling Kinetics of FtsZ Filaments Biophysical Journal. Oct, 2008 | Pubmed ID: 18621825 Monitoring Early Fusion Dynamics of Human Immunodeficiency Virus Type 1 at Single-molecule Resolution Journal of Virology. Jul, 2008 | Pubmed ID: 18480458 Fibronectin Fibrillogenesis Regulates Three-dimensional Neovessel Formation Genes & Development. May, 2008 | Pubmed ID: 18451110 Structural Requirements for the Assembly of LINC Complexes and Their Function in Cellular Mechanical Stiffness Experimental Cell Research. May, 2008 | Pubmed ID: 18396275 MinC Spatially Controls Bacterial Cytokinesis by Antagonizing the Scaffolding Function of FtsZ Current Biology : CB. Feb, 2008 | Pubmed ID: 18291654 Nuclear Lamin A/C Deficiency Induces Defects in Cell Mechanics, Polarization, and Migration Biophysical Journal. Oct, 2007 | Pubmed ID: 17631533 Probing Cellular Mechanical Responses to Stimuli Using Ballistic Intracellular Nanorheology Methods in Cell Biology. 2007 | Pubmed ID: 17613307 A Direct Interaction Between Actin and Vimentin Filaments Mediated by the Tail Domain of Vimentin The Journal of Biological Chemistry. Oct, 2006 | Pubmed ID: 16901892 Microrheology and ROCK Signaling of Human Endothelial Cells Embedded in a 3D Matrix Biophysical Journal. Nov, 2006 | Pubmed ID: 16891369 Ballistic Intracellular Nanorheology Reveals ROCK-hard Cytoplasmic Stiffening Response to Fluid Flow Journal of Cell Science. May, 2006 | Pubmed ID: 16636071 Probing Single-cell Micromechanics in Vivo: the Microrheology of C. Elegans Developing Embryos Biophysical Journal. Jun, 2006 | Pubmed ID: 16581841 Probing Intercellular Interactions Between Vascular Endothelial Cadherin Pairs at Single-molecule Resolution and in Living Cells Journal of Molecular Biology. May, 2006 | Pubmed ID: 16540120 GTPase Activity, Structure, and Mechanical Properties of Filaments Assembled from Bacterial Cytoskeleton Protein MreB Journal of Bacteriology. Feb, 2006 | Pubmed ID: 16428401 Single-molecule Analysis of Cadherin-mediated Cell-cell Adhesion Journal of Cell Science. Jan, 2006 | Pubmed ID: 16371651 Mechanics of Enveloped Virus Entry into Host Cells Biophysical Journal. Jan, 2006 | Pubmed ID: 16284274 Mechanics and Dynamics of Actin-driven Thin Membrane Protrusions Biophysical Journal. Jan, 2006 | Pubmed ID: 16214866 Single-molecule Analysis of Human Immunodeficiency Virus Type 1 Gp120-receptor Interactions in Living Cells Journal of Virology. Dec, 2005 | Pubmed ID: 16282475 Mechanical Shear Can Accelerate the Gelation of Actin Filament Networks Physical Review Letters. Jul, 2005 | Pubmed ID: 16090845 Morphology of the Lamellipodium and Organization of Actin Filaments at the Leading Edge of Crawling Cells Biophysical Journal. Nov, 2005 | Pubmed ID: 16085776 How Actin Crosslinking and Bundling Proteins Cooperate to Generate an Enhanced Cell Mechanical Response Biochemical and Biophysical Research Communications. Aug, 2005 | Pubmed ID: 15992772 The Rapid Onset of Elasticity During the Assembly of the Bacterial Cell-division Protein FtsZ Biochemical and Biophysical Research Communications. Jul, 2005 | Pubmed ID: 15950938 Cell Migration Without a Lamellipodium: Translation of Actin Dynamics into Cell Movement Mediated by Tropomyosin The Journal of Cell Biology. Feb, 2005 | Pubmed ID: 15716379 Cdc42 Mediates Nucleus Movement and MTOC Polarization in Swiss 3T3 Fibroblasts Under Mechanical Shear Stress Molecular Biology of the Cell. Feb, 2005 | Pubmed ID: 15548602 The Assembly of MreB, a Prokaryotic Homolog of Actin The Journal of Biological Chemistry. Jan, 2005 | Pubmed ID: 15548516 Intracellular Mechanics of Migrating Fibroblasts Molecular Biology of the Cell. Jan, 2005 | Pubmed ID: 15483053 Dendritic Branching and Homogenization of Actin Networks Mediated by Arp2/3 Complex Physical Review Letters. Dec, 2004 | Pubmed ID: 15697951 Intracellular Microrheology As a Tool for the Measurement of the Local Mechanical Properties of Live Cells Methods in Cell Biology. 2004 | Pubmed ID: 15646615 Structure-function Relationship of Biological Gels Revealed by Multiple-particle Tracking and Differential Interference Contrast Microscopy: the Case of Human Lamin Networks Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. Oct, 2004 | Pubmed ID: 15600434 Nuclear Envelope Breakdown Requires Overcoming the Mechanical Integrity of the Nuclear Lamina The Journal of Biological Chemistry. Oct, 2004 | Pubmed ID: 15292200 Transport of Polymeric Nanoparticle Gene Carriers in Gastric Mucus Biotechnology Progress. May-Jun, 2004 | Pubmed ID: 15176891 Distinct Kinetic and Mechanical Properties Govern Selectin-leukocyte Interactions Journal of Cell Science. May, 2004 | Pubmed ID: 15159451 Rho Kinase Regulates the Intracellular Micromechanical Response of Adherent Cells to Rho Activation Molecular Biology of the Cell. Jul, 2004 | Pubmed ID: 15146061 Micro-organization and Visco-elasticity of the Interphase Nucleus Revealed by Particle Nanotracking Journal of Cell Science. Apr, 2004 | Pubmed ID: 15090601 Real-time Intracellular Transport of Gene Nanocarriers Studied by Multiple Particle Tracking Biotechnology Progress. Mar-Apr, 2004 | Pubmed ID: 15059007 The Bimodal Role of Filamin in Controlling the Architecture and Mechanics of F-actin Networks The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14594947 Enhanced Viscoelasticity of Human Cystic Fibrotic Sputum Correlates with Increasing Microheterogeneity in Particle Transport The Journal of Biological Chemistry. Dec, 2003 | Pubmed ID: 13679362 Receptor-ligand Binding: 'catch' Bonds Finally Caught Current Biology : CB. Aug, 2003 | Pubmed ID: 12906816 The Mechanical Properties of Simple Epithelial Keratins 8 and 18: Discriminating Between Interfacial and Bulk Elasticities Journal of Structural Biology. Jul, 2003 | Pubmed ID: 12892725 Efficient Active Transport of Gene Nanocarriers to the Cell Nucleus Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12644705 A Mechanism of Coupling RCC1 Mobility to RanGTP Production on the Chromatin in Vivo The Journal of Cell Biology. Mar, 2003 | Pubmed ID: 12604592 Single Molecule Characterization of P-selectin/ligand Binding The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12522146 Micromechanical Mapping of Live Cells by Multiple-particle-tracking Microrheology Biophysical Journal. Dec, 2002 | Pubmed ID: 12496086 Effect of Length, Topology, and Concentration on the Microviscosity and Microheterogeneity of DNA Solutions Journal of Molecular Biology. Oct, 2002 | Pubmed ID: 12381315 Micromechanical Coupling Between Cell Surface Receptors and RGD Peptides Biochemical and Biophysical Research Communications. Aug, 2002 | Pubmed ID: 12176050 Functional Synergy of Actin Filament Cross-linking Proteins The Journal of Biological Chemistry. Jul, 2002 | Pubmed ID: 12006593 Microheterogeneity Controls the Rate of Gelation of Actin Filament Networks The Journal of Biological Chemistry. May, 2002 | Pubmed ID: 11889122 Pairwise Assembly Determines the Intrinsic Potential for Self-organization and Mechanical Properties of Keratin Filaments Molecular Biology of the Cell. Jan, 2002 | Pubmed ID: 11809846 The Nonhelical Tail Domain of Keratin 14 Promotes Filament Bundling and Enhances the Mechanical Properties of Keratin Intermediate Filaments in Vitro The Journal of Cell Biology. Nov, 2001 | Pubmed ID: 11724817 Shape Anisotropy of a Single Random-walk Polymer Proceedings of the National Academy of Sciences of the United States of America. Sep, 2000 | Pubmed ID: 10984514 Divisão celular dos mamíferos em matrizes 3D através de microscopia de reflexão Confocal quantitativa Lijuan He*1,2, Alexandra Sneider*1, Weitong Chen1, Michelle Karl1, Vishnu Prasath3, Pei-Hsun Wu1,2, Gunnar Mattson3, Denis Wirtz1,2,4 1Department of Chemical and Biomolecular Engineering, Johns Hopkins University, 2Johns Hopkins Physical Sciences - Oncology Center, Johns Hopkins University, 3Department of Biomedical Engineering, Johns Hopkins University, 4Departments of Oncology and Pathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine JoVE 56364 Bioengineering
Divisão celular dos mamíferos em matrizes 3D através de microscopia de reflexão Confocal quantitativa Lijuan He*1,2, Alexandra Sneider*1, Weitong Chen1, Michelle Karl1, Vishnu Prasath3, Pei-Hsun Wu1,2, Gunnar Mattson3, Denis Wirtz1,2,4 1Department of Chemical and Biomolecular Engineering, Johns Hopkins University, 2Johns Hopkins Physical Sciences - Oncology Center, Johns Hopkins University, 3Department of Biomedical Engineering, Johns Hopkins University, 4Departments of Oncology and Pathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine JoVE 56364 Bioengineering