Douglas S. Auld Chemical Biology and Therapeutics Novartis Institutes for Biomedical Research Biography Publications Institution JoVE Articles Douglas S. Auld has not added a biography. If you are Douglas S. Auld and would like to personalize this page please email our Author Liaison for assistance. Publications Characterization and Use of TurboLuc Luciferase As a Reporter for High-Throughput Assays Biochemistry. Aug, 2018 | Pubmed ID: 29641191 Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Format Applied to Yes1 Tyrosine Kinase, Glucokinase, and PI5P4Kα Lipid Kinase Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26501901 Variomics Screen Identifies the Re-entrant Loop of the Calcium-activated Chloride Channel ANO1 That Facilitates Channel Activation The Journal of Biological Chemistry. Jan, 2015 | Pubmed ID: 25425649 Composition and Applications of Focus Libraries to Phenotypic Assays Frontiers in Pharmacology. 2014 | Pubmed ID: 25104937 Biochemical, Cellular, and Biophysical Characterization of a Potent Inhibitor of Mutant Isocitrate Dehydrogenase IDH1 The Journal of Biological Chemistry. May, 2014 | Pubmed ID: 24668804 Application of Titration-Based Screening for the Rapid Pilot Testing of High-Throughput Assays Journal of Biomolecular Screening. Jun, 2014 | Pubmed ID: 24246376 Bioluminescent Assays for Cytochrome P450 Enzymes Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23475663 A Homogeneous, High-throughput Assay for Phosphatidylinositol 5-phosphate 4-kinase with a Novel, Rapid Substrate Preparation PloS One. 2013 | Pubmed ID: 23326584 Comparison of Compound Administration Methods in Biochemical Assays: Effects on Apparent Compound Potency Using Either Assay-ready Compound Plates or Pin Tool-delivered Compounds Journal of Biomolecular Screening. Jan, 2013 | Pubmed ID: 22904199 Geração de esferoides Tumor tridimensional de alta produtividade para triagem de drogas Lesley Mathews Griner1, Kalyani Gampa1, Toan Do2, Huyen Nguyen2, David Farley2, Christopher J. Hogan2, Douglas S. Auld2, Serena J. Silver1 1Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research, 2Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research JoVE 57476 Cancer Research
Geração de esferoides Tumor tridimensional de alta produtividade para triagem de drogas Lesley Mathews Griner1, Kalyani Gampa1, Toan Do2, Huyen Nguyen2, David Farley2, Christopher J. Hogan2, Douglas S. Auld2, Serena J. Silver1 1Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research, 2Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research JoVE 57476 Cancer Research