Dunja Bruder Immune Regulation Group Helmholtz Centre for Infection Research Biography Publications Institution JoVE Articles Dunja Bruder has not added a biography. If you are Dunja Bruder and would like to personalize this page please email our Author Liaison for assistance. Publications Eosinophilic Pulmonary Vasculitis As a Manifestation of the Hyperinflammatory Phase of COVID-19 The Journal of Allergy and Clinical Immunology. 01, 2021 | Pubmed ID: 33139059 Resolved Influenza A Virus Infection Has Extended Effects on Lung Homeostasis and Attenuates Allergic Airway Inflammation in a Mouse Model Microorganisms. Nov, 2020 | Pubmed ID: 33260910 NMP4: a Nuclear Driver of Innate Inflammatory Responses During Influenza A Virus Infection Cellular & Molecular Immunology. Dec, 2020 | Pubmed ID: 32747686 Topological Data Analysis to Model the Shape of Immune Responses During Co-infections Communications in Nonlinear Science & Numerical Simulation. Jun, 2020 | Pubmed ID: 32288422 ADAP Promotes Degranulation and Migration of NK Cells Primed During Infection in Mice Frontiers in Immunology. 2019 | Pubmed ID: 32038647 Mucosal CD8+ T Cell Responses Induced by an MCMV Based Vaccine Vector Confer Protection Against Influenza Challenge PLoS Pathogens. 09, 2019 | Pubmed ID: 31525249 Neutralization of Pro-inflammatory Cytokines During Secondary Infection Post Influenza A Virus Infection Frontiers in Immunology. 2019 | Pubmed ID: 31474978 The STING Activator C-di-AMP Exerts Superior Adjuvant Properties Than the Formulation Poly(I:C)/CpG After Subcutaneous Vaccination with Soluble Protein Antigen or DEC-205-mediated Antigen Targeting to Dendritic Cells Vaccine. 08, 2019 | Pubmed ID: 31320219 Essential Role of IκB for in Vivo CD4 T-cell Activation, Proliferation, and Th1-cell Differentiation During Listeria Monocytogenes Infection in Mice European Journal of Immunology. 09, 2019 | Pubmed ID: 31049948 Gamma Secretase Dependent Release of the CD44 Cytoplasmic Tail Upregulates IFI16 in Cd44-/- Tumor Cells, MEFs and Macrophages PloS One. 2018 | Pubmed ID: 30540779 Activates Human Mucosal-Associated Invariant T Cells Frontiers in Microbiology. 2018 | Pubmed ID: 30410474 Presence of Infected Gr-1CD11bCD11c Monocytic Myeloid Derived Suppressor Cells Subverts T Cell Response and Is Associated With Impaired Dendritic Cell Function in -Infected Mice Frontiers in Immunology. 2018 | Pubmed ID: 30386330 Hemodialysis-related Changes in Phenotypical Features of Monocytes Scientific Reports. 09, 2018 | Pubmed ID: 30228352 Respiratory Carriage is Associated with Broad Phenotypic Alterations of Peripheral CD4⁺CD25⁺ T Cells and Differentially Affects Immune Responses to Secondary Non-Infectious and Infectious Stimuli in Mice International Journal of Molecular Sciences. Sep, 2018 | Pubmed ID: 30200513 Proteomic Definition of Human Mucosal-associated Invariant T cells Determines Their Unique Molecular Effector Phenotype European Journal of Immunology. 08, 2018 | Pubmed ID: 29749611 Respiratory Influenza A Virus Infection Triggers Local and Systemic Natural Killer Cell Activation Toll-Like Receptor 7 Frontiers in Immunology. 2018 | Pubmed ID: 29497422 Chronic Lung Inflammation Primes Humoral Immunity and Augments Antipneumococcal Resistance Scientific Reports. 07, 2017 | Pubmed ID: 28694492 IL-33: a Jack of All Trades in the Orchestration of Respiratory Antibacterial Immunity Cellular & Molecular Immunology. Jul, 2017 | Pubmed ID: 28690328 C-REL and IκB Govern Common and Independent Steps of Regulatory T Cell Development from Novel CD122-Expressing Pre-Precursors Journal of Immunology (Baltimore, Md. : 1950). 08, 2017 | Pubmed ID: 28652399 Targeted Antigen Delivery to Dendritic Cells Elicits Robust Antiviral T Cell-mediated Immunity in the Liver Scientific Reports. Mar, 2017 | Pubmed ID: 28266658 Soluble CD200 Correlates With Interleukin-6 Levels in Sera of COPD Patients: Potential Implication of the CD200/CD200R Axis in the Disease Course Lung. 02, 2017 | Pubmed ID: 27864635 Mechanism of Granuloma Formation in Sarcoidosis Current Opinion in Hematology. 01, 2017 | Pubmed ID: 27755127 ADAP Plays a Pivotal Role in CD4+ T Cell Activation but is Only Marginally Involved in CD8+ T Cell Activation, Differentiation, and Immunity to Pathogens Journal of Leukocyte Biology. 02, 2017 | Pubmed ID: 27605210 Hierarchical Effects of Pro-inflammatory Cytokines on the Post-influenza Susceptibility to Pneumococcal Coinfection Scientific Reports. 11, 2016 | Pubmed ID: 27872472 A Cell Culture-derived Whole Virus Influenza A Vaccine Based on Magnetic Sulfated Cellulose Particles Confers Protection in Mice Against Lethal Influenza A Virus Infection Vaccine. 12, 2016 | Pubmed ID: 27816372 Influenza A Virus Infection Predisposes Hosts to Secondary Infection with Different Streptococcus Pneumoniae Serotypes with Similar Outcome but Serotype-Specific Manifestation Infection and Immunity. Dec, 2016 | Pubmed ID: 27647871 Oseltamivir PK/PD Modeling and Simulation to Evaluate Treatment Strategies Against Influenza-Pneumococcus Coinfection Frontiers in Cellular and Infection Microbiology. 2016 | Pubmed ID: 27379214 Alveolar Type II Epithelial Cells Contribute to the Anti-Influenza A Virus Response in the Lung by Integrating Pathogen- and Microenvironment-Derived Signals MBio. May, 2016 | Pubmed ID: 27143386 ImmunoPET/MR Imaging Allows Specific Detection of Aspergillus Fumigatus Lung Infection in Vivo Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26787852 Modeling Influenza Virus Infection: A Roadmap for Influenza Research Viruses. Oct, 2015 | Pubmed ID: 26473911 Erratum To: Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease Lung. Dec, 2015 | Pubmed ID: 26459043 Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease Lung. Dec, 2015 | Pubmed ID: 26319657 First Genomic Analysis of Dendritic Cells from Lung and Draining Lymph Nodes in Murine Asthma International Journal of Genomics. 2015 | Pubmed ID: 25811019 Ly6C(high) Monocytes Control Cerebral Toxoplasmosis Journal of Immunology (Baltimore, Md. : 1950). Apr, 2015 | Pubmed ID: 25710908 Evidence for a Causal Link Between Adaptor Protein PDZK1 Downregulation and Na⁺/H⁺ Exchanger NHE3 Dysfunction in Human and Murine Colitis Pflugers Archiv : European Journal of Physiology. Aug, 2015 | Pubmed ID: 25271043 Attenuation of Immune-mediated Influenza Pneumonia by Targeting the Inducible Co-stimulator (ICOS) Molecule on T Cells PloS One. 2014 | Pubmed ID: 25029240 Interferon Regulatory Factor-1 Protects from Fatal Neurotropic Infection with Vesicular Stomatitis Virus by Specific Inhibition of Viral Replication in Neurons PLoS Pathogens. Mar, 2014 | Pubmed ID: 24675692 ChIP-on-chip Analisi Identifica IL 22 Come Gene Bersaglio Diretto Del Fattore Di Trascrizione FOXP3 Ectopically Espressa Nelle Cellule T Umane BMC Genomics. Dec, 2012 | Pubmed ID: 23244505 TLR7 Contribuisce a Rapida Progressione, Ma Non La Complessiva Fatale Esito Del Secondario Pneumococco Dopo Infezione Da Virus Dell'Influenza A Journal of Innate Immunity. Nov, 2012 | Pubmed ID: 23154432 IL-4 Attenua Soppressione Epiteliale Polmonare Cellulo-mediata Di Adescamento Delle Cellule T PloS One. 2012 | Pubmed ID: 23029313 CD8 + Cellule T Risponde a Alveolare Espressione Di CD25 Mancanza Di Auto-antigene E Non Riescono a Far Precipitare L'autoimmunità American Journal of Respiratory Cell and Molecular Biology. Dec, 2012 | Pubmed ID: 22984087 Intervento Terapeutico in Cancro E Infezioni Virali Croniche: Anticorpo Mediata Manipolazione Dell'interazione PD-1/PD-L1 Reviews on Recent Clinical Trials. Feb, 2012 | Pubmed ID: 22023178 Mappatura QTL Espressione Nella Regolamentazione E Cellule T Helper Dalla Famiglia Dei Ceppi BXD Rivela Nuovi Geni Specifici Delle Cellule, Le Interazioni Gene-gene E Geni Candidati Per Malattia Auto-immune BMC Genomics. 2011 | Pubmed ID: 22182475 Sorveglianza Di Senescenza Di Epatociti Pre-maligne Limita Lo Sviluppo Di Cancro Al Fegato Nature. Nov, 2011 | Pubmed ID: 22080947 Umane Cellule T Regolatorie Nel Trapianto Di Cellule Staminali Allogeniche Blood. Sep, 2011 | Pubmed ID: 21778340 New Insights into La Patologia Molecolare Della Pneumopathy Indotta Da Radiazioni Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Oct, 2011 | Pubmed ID: 21722981 Sono Dispensabili Per Il Controllo Di CD8 + Infiammazione Polmonare Mediata Da Cellule T CD4 + CD25 + Foxp3 + Cellule T Regolatorie Journal of Immunology (Baltimore, Md. : 1950). Jun, 2011 | Pubmed ID: 21518973 Inibizione Del Traffico Dei Linfociti Protegge Il Cervello Contro Neuroinflammation Deleteri Dopo Ictus Brain : a Journal of Neurology. Mar, 2011 | Pubmed ID: 21354973 CX3CR1 + CD8alpha + Le Cellule Dendritiche Sono Una Popolazione Di Steady-stata Correlata Alle Cellule Dendritiche Plasmacytoid Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010 | Pubmed ID: 20679228 Topo Reporter Romanzo Rivela Espressione Costitutiva E Infiammatorie IFN-beta in Vivo Journal of Immunology (Baltimore, Md. : 1950). Sep, 2009 | Pubmed ID: 19667093 Profilo Di Espressione Genica E Frequenza Di Cellule T Regolatorie Nel Carcinoma a Cellule Renali Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. 2009 | Pubmed ID: 19609102 Host Background Genetico Influenza Fortemente La Risposta All'influenza a Infezioni Da Virus PloS One. 2009 | Pubmed ID: 19293935 Aumento Della Suscettibilità Per Superinfezione Con Streptococcus Pneumoniae Durante L'infezione Da Virus Dell'influenza Non è Causato Da Linfopenia TLR7-mediata PloS One. 2009 | Pubmed ID: 19290047 Cellule Epiteliali Alveolari Di Tipo II Presentano L'antigene Alle Cellule T CD4(+) E Inducono Le Cellule T Regolatorie Foxp3(+) American Journal of Respiratory and Critical Care Medicine. Mar, 2009 | Pubmed ID: 19096007 Probiotici Escherichia Coli Nissle 1917 Inibisce Leaky Gut Da Rafforzare L'integrità Della Mucosa PloS One. 2007 | Pubmed ID: 18074031 Stimolazione Cronica Dell'antigene in Vivo Induce Una Distinta Popolazione Di Cellule T Regolatorie Di Antigene-specifiche Foxp3 CD25 Journal of Immunology (Baltimore, Md. : 1950). Dec, 2007 | Pubmed ID: 18056346 Alterazioni Fenotipiche in Tipo II Epiteliale Cellule Alveolari in Cellule T CD4 + Mediato Infiammazione Polmonare Respiratory Research. 2007 | Pubmed ID: 17610738 Antigene Epiteliale Intestinale Induce Le Cellule T CD4 + Con Fenotipo Normativo in Un Modello Murino Transgenico Autoimmuni Annals of the New York Academy of Sciences. Aug, 2006 | Pubmed ID: 17057222 Autoimmune-mediata Infiammazione Intestinale-impatto E Regolamento Delle Cellule CD8 + T Antigene-specifiche Gastroenterology. Aug, 2006 | Pubmed ID: 16890605 Lesioni Del Polmone E L'immunità Cellulare Nell'infezione Da Virus Respiratorio Viral Immunology. 2006 | Pubmed ID: 16817757 Sovraespressione Dei Recettori Accoppiati a Proteine 83 G in Ingenuo CD4 + CD25-cellule T Porta Ad Induzione Di Foxp3 + Cellule T Regolatorie in Vivo Journal of Immunology (Baltimore, Md. : 1950). Jul, 2006 | Pubmed ID: 16785516 Polmone Epiteliali NF-kappaB E Stat1 Segnalazione in Risposta Al Riconoscimento Dell'antigene Di CD8 + T Cell Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. May, 2006 | Pubmed ID: 16689660 Più Sinergica Fattori Che Contribuiscono Alla Resistenza Della Risposta Delle Cellule T CD8 + Contro Listeriolysin O International Immunology. Jan, 2006 | Pubmed ID: 16291651 Sul Bordo Della Autoimmunità: Stimolazione Delle Cellule T Da Cellule Dendritiche Stazionario Previene Diabete Autoimmune Diabetes. Dec, 2005 | Pubmed ID: 16306354 Immunità Intestinale Di Escherichia Coli NISSLE 1917: Un Vettore Sicuro Per Molecole Terapeutiche FEMS Immunology and Medical Microbiology. Mar, 2005 | Pubmed ID: 15708311 Caratterizzazione Di Una Sottopopolazione Di Cellule Linfoidi B220 + Con Funzioni Immunitarie Schematizzate Nei Tessuti Linfoidi Associati Nasale Journal of Immunology (Baltimore, Md. : 1950). Feb, 2005 | Pubmed ID: 15661888 CD4 Malattia Polmonare Mediata Dei Linfociti T: Stazionario Tra Patologico E Tollerogenico Reazioni Immunitarie American Journal of Respiratory and Critical Care Medicine. Dec, 2004 | Pubmed ID: 15306530 Neuropilin-1: Un Marcatore Di Superficie Delle Cellule T Regolatorie European Journal of Immunology. Mar, 2004 | Pubmed ID: 14991591 Coniugazione chimica di un anticorpo purificato dec-205 diretto con proteina a lunghezza intera per il targeting di cellule dendritiche di topo in vitro e in vivo Julia Volckmar1,2, Laura Knop1,2,3, Tatjana Hirsch1, Sarah Frentzel1,2, Christian Erck4, Marco van Ham4, Sabine Stegemann-Koniszewski*1,2,5, Dunja Bruder*1,2 1Immune Regulation Group, Helmholtz Centre for Infection Research, 2Infection Immunology Group, Institute of Medical Microbiology, Infection Prevention and Control, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 3Institute for Molecular and Clinical Immunology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 4Cellular Proteome Research, Helmholtz Centre for Infection Research, 5Experimental Pneumology, University Hospital of Pneumology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg JoVE 62018 Cancer Research Flusso Isolamento citometrica di primari murini di tipo II cellule alveolari epiteliali per gli studi funzionali e molecolari Marcus Gereke1,2, Andrea Autengruber1,2, Lothar Gröbe3, Andreas Jeron2, Dunja Bruder1,2, Sabine Stegemann-Koniszewski1 1Research Group Immune Regulation, Helmholtz Centre for Infection Research, 2Research Group Infection Immunology, Institute of Medical Microbiology, Otto-von-Guericke University, 3Department of Experimental Immunology, Helmholtz Centre for Infection Research JoVE 4322 Immunology and Infection
Coniugazione chimica di un anticorpo purificato dec-205 diretto con proteina a lunghezza intera per il targeting di cellule dendritiche di topo in vitro e in vivo Julia Volckmar1,2, Laura Knop1,2,3, Tatjana Hirsch1, Sarah Frentzel1,2, Christian Erck4, Marco van Ham4, Sabine Stegemann-Koniszewski*1,2,5, Dunja Bruder*1,2 1Immune Regulation Group, Helmholtz Centre for Infection Research, 2Infection Immunology Group, Institute of Medical Microbiology, Infection Prevention and Control, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 3Institute for Molecular and Clinical Immunology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 4Cellular Proteome Research, Helmholtz Centre for Infection Research, 5Experimental Pneumology, University Hospital of Pneumology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg JoVE 62018 Cancer Research
Flusso Isolamento citometrica di primari murini di tipo II cellule alveolari epiteliali per gli studi funzionali e molecolari Marcus Gereke1,2, Andrea Autengruber1,2, Lothar Gröbe3, Andreas Jeron2, Dunja Bruder1,2, Sabine Stegemann-Koniszewski1 1Research Group Immune Regulation, Helmholtz Centre for Infection Research, 2Research Group Infection Immunology, Institute of Medical Microbiology, Otto-von-Guericke University, 3Department of Experimental Immunology, Helmholtz Centre for Infection Research JoVE 4322 Immunology and Infection