Eiji Shigetomi Department of Neuropharmacology, Faculty of Medicine University of Yamanashi Biography Publications Institution JoVE Articles Eiji Shigetomi has not added a biography. If you are Eiji Shigetomi and would like to personalize this page please email our Author Liaison for assistance. Publications Transient Astrocytic MGluR5 Expression Drives Synaptic Plasticity and Subsequent Chronic Pain in Mice The Journal of Experimental Medicine. 04, 2022 | Pubmed ID: 35319723 Effects of Fatty Acid Metabolites on Nocturia Scientific Reports. 02, 2022 | Pubmed ID: 35197540 Abnormal Ca Signals in Reactive Astrocytes As a Common Cause of Brain Diseases International Journal of Molecular Sciences. Dec, 2021 | Pubmed ID: 35008573 Adenosine A Receptor Down-regulates Metabotropic Glutamate Receptor 5 in Astrocytes During Postnatal Development Glia. 11, 2021 | Pubmed ID: 34339538 Transnasal Transplantation of Human Induced Pluripotent Stem Cell-derived Microglia to the Brain of Immunocompetent Mice Glia. 10, 2021 | Pubmed ID: 34309082 Different Effects of GsMTx4 on Nocturia Associated with the Circadian Clock and Piezo1 Expression in Mice Life Sciences. Aug, 2021 | Pubmed ID: 33930366 Reactive Astrocyte-driven Epileptogenesis is Induced by Microglia Initially Activated Following Status Epilepticus JCI Insight. 05, 2021 | Pubmed ID: 33830944 Author Correction: Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. Nov, 2019 | Pubmed ID: 31700120 Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. 07, 2019 | Pubmed ID: 31296902 Aberrant Calcium Signals in Reactive Astrocytes: A Key Process in Neurological Disorders International Journal of Molecular Sciences. Feb, 2019 | Pubmed ID: 30823575 The Time-dependent Variation of ATP Release in Mouse Primary-cultured Urothelial Cells is Regulated by the Clock Gene Neurourology and Urodynamics. 11, 2018 | Pubmed ID: 30106187 Anti-Depressant Fluoxetine Reveals Its Therapeutic Effect Via Astrocytes EBioMedicine. Jun, 2018 | Pubmed ID: 29887330 The Oscillation of Intracellular Ca Influx Associated with the Circadian Expression of Piezo1 and TRPV4 in the Bladder Urothelium Scientific Reports. 04, 2018 | Pubmed ID: 29632308 Aberrant Astrocyte Ca Signals "AxCa Signals" Exacerbate Pathological Alterations in an Alexander Disease Model Glia. 05, 2018 | Pubmed ID: 29383757 Role of Purinergic Receptor P2Y1 in Spatiotemporal Ca Dynamics in Astrocytes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 02, 2018 | Pubmed ID: 29305530 The Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT, Associated with the Expression Levels of the Clock Genes in Mouse Primary Cultured Urothelial Cells Neurourology and Urodynamics. 03, 2018 | Pubmed ID: 28881406 Author Correction: Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 11, 2017 | Pubmed ID: 29138397 Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence Neuron. Aug, 2017 | Pubmed ID: 28712653 Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 06, 2017 | Pubmed ID: 28642575 Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia Via P2Y Receptor Downregulation Cell Reports. 05, 2017 | Pubmed ID: 28494865 P2Y-deficiency Increases Micturition Frequency and Attenuates Sustained Contractility of the Urinary Bladder in Mice Scientific Reports. 04, 2017 | Pubmed ID: 28396595 Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa PloS One. 2017 | Pubmed ID: 28060940 The Clock Mutant Mouse is a Novel Experimental Model for Nocturia and Nocturnal Polyuria Neurourology and Urodynamics. Apr, 2017 | Pubmed ID: 27348079 Urothelial ATP Exocytosis: Regulation of Bladder Compliance in the Urine Storage Phase Scientific Reports. 07, 2016 | Pubmed ID: 27412485 Cortical Astrocytes Rewire Somatosensory Cortical Circuits for Peripheral Neuropathic Pain The Journal of Clinical Investigation. May, 2016 | Pubmed ID: 27064281 Probing the Complexities of Astrocyte Calcium Signaling Trends in Cell Biology. Apr, 2016 | Pubmed ID: 26896246 Müller Cell-mediated Neurite Outgrowth of the Retinal Ganglion Cells Via P2Y Receptor Signals Journal of Neurochemistry. Feb, 2016 | Pubmed ID: 26560804 Imaging Calcium Microdomains Within Entire Astrocyte Territories and Endfeet with GCaMPs Expressed Using Adeno-associated Viruses The Journal of General Physiology. May, 2013 | Pubmed ID: 23589582 TRPA1チャネルは、GAT-3を介してアストロ休憩カルシウムと抑制性シナプスの有効性を調節する Nature Neuroscience. Jan, 2012 | Pubmed ID: 22158513 ニューロンのP2X2受容体は活性化されると細胞膜情報モバイルATPセンサーです The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2011 | Pubmed ID: 22090499 [アストロ サイトによるシナプス調節]。 Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Oct, 2011 | Pubmed ID: 21986065 アストロ生理学を研究するためにカルシウム指示薬染料のバルクロード:形態学的マップを使用したキーの制限事項と改善点 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2011 | Pubmed ID: 21697385 改良された膜ターゲットGCaMPレポーターとアストロカルシウムミクロドメインを監視する Neuron Glia Biology. Dec, 2010 | Pubmed ID: 21205365 アストロプロセスでカルシウムシグナルを監視するように遺伝子をターゲット光学センサー Nature Neuroscience. Jun, 2010 | Pubmed ID: 20495558 アストロカルシウム興奮の2つの形態では、錐体細胞におけるNMDA受容体媒介遅い内向き電流に特殊効果を持つ The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2008 | Pubmed ID: 18579739 In Vitroおよびin Vivoで追跡トランスミッタゲートP2X陽イオンチャネルの活性化 Nature Methods. Jan, 2008 | Pubmed ID: 18084300 [脳シナプスにおけるプリン規制コンプレックス]。 Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2007 | Pubmed ID: 17633523 無酸素症による自発的なグリシン リリースの円滑化 NMDA 受容体のラット舌下神経運動ニューロンの現在を増強します。 The European Journal of Neuroscience. Mar, 2007 | Pubmed ID: 17408431 グルタミン酸の基になるブロッカー耐性シナプス電位依存性 Ca 2 + チャネル マウス核孤束脈でリリースします。 Brain Research. Aug, 2006 | Pubmed ID: 16814754 細胞外 ATP 核孤束脈ネットワークの周波数フィルタ リングによる演奏デュアル ロール。 Advances in Experimental Medicine and Biology. 2004 | Pubmed ID: 15602957 活動電位に依存しないリリース グルタミン酸による Ca 2 + エントリをシナプス前 P2X 受容体を介しての脳幹部の自律神経ネットワークにおけるシナプス後発火を引き出します。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2004 | Pubmed ID: 15044552 ATP とアデノシン-中枢神経系を介するシグナル伝達機構: シナプス機構に関する研究: その「デュアル役割」を演じる ATP のステージ。 Journal of Pharmacological Sciences. Feb, 2004 | Pubmed ID: 14978346 微分は次の迷走神経セクション ラット迷走神経の遠心性ニューロンにおける P2X 受容体レベルで増加します。 Brain Research. Jul, 2003 | Pubmed ID: 12788520 パッチ ・ クランプの脳幹のスライスを記録によってシナプス伝達を制御する分子機構の解析 Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Apr, 2003 | Pubmed ID: 12777844 インビボ 大きな頭蓋窓を用いたマウスからの広視野および2光子カルシウムイメージング Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 Neuroscience ヒト人工多能性幹細胞由来ミクログリアの免疫適格マウス脳への非侵襲的経鼻経路による移植 Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 Neuroscience アストロサイトの細胞膜とグローバル細胞内カルシウム動態の近くの測定 Eiji Shigetomi1, Baljit S. Khakh1 1Departments of Physiology and Neurobiology, David Geffen School of Medicine, University of California, Los Angeles JoVE 1142 Biology
インビボ 大きな頭蓋窓を用いたマウスからの広視野および2光子カルシウムイメージング Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 Neuroscience
ヒト人工多能性幹細胞由来ミクログリアの免疫適格マウス脳への非侵襲的経鼻経路による移植 Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 Neuroscience
アストロサイトの細胞膜とグローバル細胞内カルシウム動態の近くの測定 Eiji Shigetomi1, Baljit S. Khakh1 1Departments of Physiology and Neurobiology, David Geffen School of Medicine, University of California, Los Angeles JoVE 1142 Biology