In JoVE (1)
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Articles by Elena Reinhard in JoVE
Rapid In Vivo Assessment of Adjuvant's Cytotoxic T Lymphocytes Generation Capabilities for Vaccine Development Darío Lirussi1, Thomas Ebensen1, Kai Schulze1, Elena Reinhard1, Stephanie Trittel1, Peggy Riese1, Blair Prochnow1, Carlos A. Guzmán1 1Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research We present here an application for a standard immunological technique (CFSE stained OT-I proliferation) intended to rapidly monitor adjuvant-mediated cytotoxic T lymphocyte (CTL) generation in vivo. This fast estimation of CTL capacities is useful for the development of prophylactic vaccines against intracellular pathogens as well as therapeutic cancer vaccines.