Frank Maldarelli The virology Core at the HIV Drug Resistance Program NCI-Frederick Biography Publications Institution JoVE Articles Frank Maldarelli has not added a biography. If you are Frank Maldarelli and would like to personalize this page please email our Author Liaison for assistance. Publications Short-course Raltegravir Intensification Does Not Increase 2 Long Terminal Repeat Episomal HIV-1 DNA in Patients on Effective Antiretroviral Therapy Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Feb, 2012 | Pubmed ID: 22016501 Short-course Combivir After Single-dose Nevirapine Reduces but Does Not Eliminate the Emergence of Nevirapine Resistance in Women Antiviral Therapy. Nov, 2011 | Pubmed ID: 22293443 Clinical Management of HIV Drug Resistance Viruses. Apr, 2011 | Pubmed ID: 21994737 Genotypic Resistance at Viral Rebound Among Patients Who Received Lopinavir/ritonavir-based or Efavirenz-based First Antiretroviral Therapy in South Africa Journal of Acquired Immune Deficiency Syndromes (1999). Nov, 2011 | Pubmed ID: 21694608 Majority of CD4+ T Cells from Peripheral Blood of HIV-1-infected Individuals Contain Only One HIV DNA Molecule Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21690402 Transmitted Raltegravir Resistance in an HIV-1 CRF_AG-infected Patient Antiviral Therapy. 2011 | Pubmed ID: 21447876 Estimate of Effective Recombination Rate and Average Selection Coefficient for HIV in Chronic Infection Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21436045 High Dose Atorvastatin Decreases Cellular Markers of Immune Activation Without Affecting HIV-1 RNA Levels: Results of a Double-blind Randomized Placebo Controlled Clinical Trial The Journal of Infectious Diseases. Mar, 2011 | Pubmed ID: 21325137 CD4 and CD8 T Cell Immune Activation During Chronic HIV Infection: Roles of Homeostasis, HIV, Type I IFN, and IL-7 Journal of Immunology (Baltimore, Md. : 1950). Feb, 2011 | Pubmed ID: 21257970 Targeting Viral Reservoirs: Ability of Antiretroviral Therapy to Stop Viral Replication Current Opinion in HIV and AIDS. Jan, 2011 | Pubmed ID: 21228755 Genetic Diversity of Simian Immunodeficiency Virus Encoding HIV-1 Reverse Transcriptase Persists in Macaques Despite Antiretroviral Therapy Journal of Virology. Jan, 2011 | Pubmed ID: 21084490 Characterization of the Meiosis-specific Recombinase Dmc1 of Pneumocystis The Journal of Infectious Diseases. Dec, 2010 | Pubmed ID: 21050123 XMRV: a New Virus in Prostate Cancer? Cancer Research. Dec, 2010 | Pubmed ID: 20966126 Current Status of Xenotropic Murine Leukemia Virus-related Retrovirus in Chronic Fatigue Syndrome and Prostate Cancer: Reach for a Scorecard, Not a Prescription Pad The Journal of Infectious Diseases. Nov, 2010 | Pubmed ID: 20936981 HIV-1 Continues to Replicate and Evolve in Patients with Natural Control of HIV Infection Journal of Virology. Dec, 2010 | Pubmed ID: 20926564 Patterns of Human Immunodeficiency Virus Type 1 Recombination Ex Vivo Provide Evidence for Coadaptation of Distant Sites, Resulting in Purifying Selection for Intersubtype Recombinants During Replication Journal of Virology. Aug, 2010 | Pubmed ID: 20504919 Comparison of Standard PCR/cloning to Single Genome Sequencing for Analysis of HIV-1 Populations Journal of Virological Methods. Sep, 2010 | Pubmed ID: 20451557 Optimization of Allele-specific PCR Using Patient-specific HIV Consensus Sequences for Primer Design Journal of Virological Methods. Mar, 2010 | Pubmed ID: 19948190 RT-SHIV Subpopulation Dynamics in Infected Macaques During Anti-HIV Therapy Retrovirology. 2009 | Pubmed ID: 19889213 Subtype-specific Differences in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Connection Subdomain of CRF01_AE Are Associated with Higher Levels of Resistance to 3'-azido-3'-deoxythymidine Journal of Virology. Sep, 2009 | Pubmed ID: 19553318 Evaluation of the Pathogenesis of Decreasing CD4(+) T Cell Counts in Human Immunodeficiency Virus Type 1-infected Patients Receiving Successfully Suppressive Antiretroviral Therapy The Journal of Infectious Diseases. Jun, 2009 | Pubmed ID: 19432547 Regimen Simplification to Atazanavir-ritonavir Alone As Maintenance Antiretroviral Therapy: Final 48-week Clinical and Virologic Outcomes The Journal of Infectious Diseases. Mar, 2009 | Pubmed ID: 19191590 Inferiority of IL-2 Alone Versus IL-2 with HAART in Maintaining CD4 T Cell Counts During HAART Interruption: a Randomized Controlled Trial AIDS (London, England). Jan, 2009 | Pubmed ID: 19098490 Lytic Granule Loading of CD8+ T Cells is Required for HIV-infected Cell Elimination Associated with Immune Control Immunity. Dec, 2008 | Pubmed ID: 19062316 Iatrogenic Cushing Syndrome After Epidural Triamcinolone Injections in an HIV Type 1-infected Patient Receiving Therapy with Ritonavir-lopinavir Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Dec, 2008 | Pubmed ID: 18991509 Efavirenz Induces CYP2B6-mediated Hydroxylation of Bupropion in Healthy Subjects Journal of Acquired Immune Deficiency Syndromes (1999). Dec, 2008 | Pubmed ID: 18989234 Variation in the Major Surface Glycoprotein Genes in Pneumocystis Jirovecii The Journal of Infectious Diseases. Sep, 2008 | Pubmed ID: 18627244 Low-level Viremia Persists for at Least 7 Years in Patients on Suppressive Antiretroviral Therapy Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008 | Pubmed ID: 18332425 Frequent Polymorphism at Drug Resistance Sites in HIV-1 Protease and Reverse Transcriptase AIDS (London, England). Feb, 2008 | Pubmed ID: 18301062 Suppression of Viremia and Evolution of Human Immunodeficiency Virus Type 1 Drug Resistance in a Macaque Model for Antiretroviral Therapy Journal of Virology. Nov, 2007 | Pubmed ID: 17855539 ART Suppresses Plasma HIV-1 RNA to a Stable Set Point Predicted by Pretherapy Viremia PLoS Pathogens. Apr, 2007 | Pubmed ID: 17411338 Enfuvirtide Antiviral Activity Despite Rebound Viremia and Resistance Mutations: Fitness Tampering or a Case of Persistent Braking on Entering? The Journal of Infectious Diseases. Feb, 2007 | Pubmed ID: 17205468 Mutations in the Connection Domain of HIV-1 Reverse Transcriptase Increase 3'-azido-3'-deoxythymidine Resistance Proceedings of the National Academy of Sciences of the United States of America. Jan, 2007 | Pubmed ID: 17179211 Tenofovir Disoproxil Fumarate and an Optimized Background Regimen of Antiretroviral Agents As Salvage Therapy: Impact on Bone Mineral Density in HIV-infected Children Pediatrics. Sep, 2006 | Pubmed ID: 16923923 Consistent Effects of TSG101 Genetic Variability on Multiple Outcomes of Exposure to Human Immunodeficiency Virus Type 1 Journal of Virology. Jul, 2006 | Pubmed ID: 16809281 Selection and Persistence of Non-nucleoside Reverse Transcriptase Inhibitor-resistant HIV-1 in Patients Starting and Stopping Non-nucleoside Therapy AIDS (London, England). Mar, 2006 | Pubmed ID: 16514300 Tenofovir Disoproxil Fumarate and an Optimized Background Regimen of Antiretroviral Agents As Salvage Therapy for Pediatric HIV Infection Pediatrics. Dec, 2005 | Pubmed ID: 16291735 Pravastatin Does Not Have a Consistent Antiviral Effect in Chronically HIV-infected Individuals on Antiretroviral Therapy AIDS (London, England). Jul, 2005 | Pubmed ID: 15958846 Mechanisms of Nonrandom Human Immunodeficiency Virus Type 1 Infection and Double Infection: Preference in Virus Entry is Important but is Not the Sole Factor Journal of Virology. Apr, 2005 | Pubmed ID: 15767415 Mechanism for Nucleoside Analog-mediated Abrogation of HIV-1 Replication: Balance Between RNase H Activity and Nucleotide Excision Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15684061 Multiple, Linked Human Immunodeficiency Virus Type 1 Drug Resistance Mutations in Treatment-experienced Patients Are Missed by Standard Genotype Analysis Journal of Clinical Microbiology. Jan, 2005 | Pubmed ID: 15635002 Prion Diseases: Update on Mad Cow Disease, Variant Creutzfeldt-Jakob Disease, and the Transmissible Spongiform Encephalopathies Current Infectious Disease Reports. Aug, 2004 | Pubmed ID: 15265460 A Proof-of-concept Study of Short-cycle Intermittent Antiretroviral Therapy with a Once-daily Regimen of Didanosine, Lamivudine, and Efavirenz for the Treatment of Chronic HIV Infection The Journal of Infectious Diseases. Jun, 2004 | Pubmed ID: 15143462 Changes in Hepatitis C Viral Response After Initiation of Highly Active Antiretroviral Therapy and Control of HIV Viremia in Chronically Co-infected Individuals HIV Clinical Trials. Jan-Feb, 2004 | Pubmed ID: 15002084 Nonrandom HIV-1 Infection and Double Infection Via Direct and Cell-mediated Pathways Proceedings of the National Academy of Sciences of the United States of America. Jan, 2004 | Pubmed ID: 14707263 New Real-time Reverse Transcriptase-initiated PCR Assay with Single-copy Sensitivity for Human Immunodeficiency Virus Type 1 RNA in Plasma Journal of Clinical Microbiology. Oct, 2003 | Pubmed ID: 14532178 Innate Immunity in Human Immunodeficiency Virus Infection: Effect of Viremia on Natural Killer Cell Function The Journal of Infectious Diseases. Apr, 2003 | Pubmed ID: 12660917 HIV-1 Fitness and Replication Capacity: What Are They and Can They Help in Patient Management? Current Infectious Disease Reports. Feb, 2003 | Pubmed ID: 12525294 Amplificar e Quantificação do HIV-1 RNA no indivíduos infectados pelo HIV com carga viral abaixo do limite de detecção pela Standard Ensaios Clínicos Helene Mens1, Mary Kearney1, Ann Wiegand1, Jonathan Spindler1, Frank Maldarelli1, John W. Mellors2, John M. Coffin3 1The virology Core at the HIV Drug Resistance Program, NCI-Frederick, 2Division of Infectious Diseases, University of Pittsburgh, 3Department of Molecular Biology and Microbiology, Tuffts University JoVE 2960 Immunology and Infection
Amplificar e Quantificação do HIV-1 RNA no indivíduos infectados pelo HIV com carga viral abaixo do limite de detecção pela Standard Ensaios Clínicos Helene Mens1, Mary Kearney1, Ann Wiegand1, Jonathan Spindler1, Frank Maldarelli1, John W. Mellors2, John M. Coffin3 1The virology Core at the HIV Drug Resistance Program, NCI-Frederick, 2Division of Infectious Diseases, University of Pittsburgh, 3Department of Molecular Biology and Microbiology, Tuffts University JoVE 2960 Immunology and Infection
