Frederick A. Villamena

Publications

• Guest Inclusion in Cucurbiturils Studied by ESR and DFT: The Case of Nitroxide Radicals and Spin Adducts of DMPO and MNP
  The Journal of Physical Chemistry. A. Aug, 2012  |   Pubmed ID: 22830598
• Reactive Nitrogen Species Reactivities with Nitrones: Theoretical and Experimental Studies
  Chemical Research in Toxicology. Jul, 2012  |   Pubmed ID: 22775566
• Potential Implication of the Chemical Properties and Bioactivity of Nitrone Spin Traps for Therapeutics
  Future Medicinal Chemistry. Jun, 2012  |   Pubmed ID: 22709256
• Theoretical and Experimental Studies of the Spin Trapping of Inorganic Radicals by 5,5-Dimethyl-1-pyrroline N-Oxide (DMPO). 3. Sulfur Dioxide, Sulfite, and Sulfate Radical Anions
  The Journal of Physical Chemistry. A. Jul, 2012  |   Pubmed ID: 22668066
• Inhibition of ROS-induced Apoptosis in Endothelial Cells by Nitrone Spin Traps Via Induction of Phase II Enzymes and Suppression of Mitochondria-dependent Pro-apoptotic Signaling
  Biochemical Pharmacology. Aug, 2012  |   Pubmed ID: 22580046
• Synthesis of Tris-hydroxymethyl-based Nitrone Derivatives with Highly Reactive Nitronyl Carbon
  The Journal of Organic Chemistry. Jan, 2012  |   Pubmed ID: 22188016
• Reactivities of Superoxide and Hydroperoxyl Radicals with Disubstituted Cyclic Nitrones: a DFT Study
  The Journal of Physical Chemistry. A. Jan, 2012  |   Pubmed ID: 22085265
• Physicochemical and Toxicological Properties of Commercial Carbon Blacks Modified by Reaction with Ozone
  Environmental Science & Technology. Dec, 2011  |   Pubmed ID: 22054302
• Synthesis of Trityl Radical-conjugated Disulfide Biradicals for Measurement of Thiol Concentration
  The Journal of Organic Chemistry. May, 2011  |   Pubmed ID: 21488696
• Fast Reactivity of a Cyclic Nitrone-Calix[4]pyrrole Conjugate with Superoxide Radical Anion: Theoretical and Experimental Studies (†)
  Journal of the American Chemical Society. Nov, 2010  |   Pubmed ID: 21070040
• Synthesis of (14)N- and (15)N-labeled Trityl-nitroxide Biradicals with Strong Spin-Spin Interaction and Improved Sensitivity to Redox Status and Oxygen
  The Journal of Organic Chemistry. Oct, 2010  |   Pubmed ID: 21028905
• Amphiphilic Amide Nitrones: a New Class of Protective Agents Acting As Modifiers of Mitochondrial Metabolism
  Journal of Medicinal Chemistry. Jul, 2010  |   Pubmed ID: 20527971
• Trityl-nitroxide Biradicals As Unique Molecular Probes for the Simultaneous Measurement of Redox Status and Oxygenation
  Chemical Communications (Cambridge, England). Jan, 2010  |   Pubmed ID: 20062884
• Superoxide Radical Anion Adduct of 5,5-dimethyl-1-pyrroline N-oxide. 6. Redox Properties
  The Journal of Physical Chemistry. A. Jan, 2010  |   Pubmed ID: 19968309
• Perchlorotrityl Radical-fluorophore Conjugates As Dual Fluorescence and EPR Probes for Superoxide Radical Anion
  Bioorganic & Medicinal Chemistry. Jan, 2010  |   Pubmed ID: 19963389
• Spin Trapping and Cytoprotective Properties of Fluorinated Amphiphilic Carrier Conjugates of Cyclic Versus Linear Nitrones
  Chemical Research in Toxicology. Sep, 2009  |   Pubmed ID: 19678661
• Lipophilic Beta-cyclodextrin Cyclic-nitrone Conjugate: Synthesis and Spin Trapping Studies
  The Journal of Organic Chemistry. Aug, 2009  |   Pubmed ID: 19530689
• Superoxide Radical Anion Adduct of 5,5-dimethyl-1-pyrroline N-oxide. 5. Thermodynamics and Kinetics of Unimolecular Decomposition
  The Journal of Physical Chemistry. A. Jun, 2009  |   Pubmed ID: 19425559
• The Radical Trap 5,5-dimethyl-1-pyrroline N-oxide Exerts Dose-dependent Protection Against Myocardial Ischemia-reperfusion Injury Through Preservation of Mitochondrial Electron Transport
  The Journal of Pharmacology and Experimental Therapeutics. May, 2009  |   Pubmed ID: 19201989
• Esterified Trityl Radicals As Intracellular Oxygen Probes
  Free Radical Biology & Medicine. Apr, 2009  |   Pubmed ID: 19135524
• Superoxide Radical Anion Adduct of 5,5-dimethyl-1-pyrroline N-oxide. 4. Conformational Effects on the EPR Hyperfine Splitting Constants
  The Journal of Physical Chemistry. A. Dec, 2008  |   Pubmed ID: 19012384
• Reactivity of Superoxide Radical Anion and Hydroperoxyl Radical with Alpha-phenyl-N-tert-butylnitrone (PBN) Derivatives
  The Journal of Physical Chemistry. A. Dec, 2008  |   Pubmed ID: 18998656
• Theoretical and Experimental Studies of Tyrosyl Hydroperoxide Formation in the Presence of H-bond Donors
  Chemical Research in Toxicology. Oct, 2008  |   Pubmed ID: 18816073
• Highly Stable Dendritic Trityl Radicals As Oxygen and PH Probe
  Chemical Communications (Cambridge, England). Sep, 2008  |   Pubmed ID: 18802562
• Improved Spin Trapping Properties by Beta-cyclodextrin-cyclic Nitrone Conjugate
  The Journal of Organic Chemistry. Sep, 2008  |   Pubmed ID: 18707169
• Synthesis and Spin-trapping Properties of a New Spirolactonyl Nitrone
  The Journal of Organic Chemistry. Apr, 2008  |   Pubmed ID: 18331054
• Superoxide Radical Anion Adduct of 5,5-dimethyl-1-pyrroline N-oxide (DMPO). 3. Effect of Mildly Acidic PH on the Thermodynamics and Kinetics of Adduct Formation
  The Journal of Physical Chemistry. A. Mar, 2008  |   Pubmed ID: 18303874
• Synthesis and Characterization of Ester-derivatized Tetrathiatriarylmethyl Radicals As Intracellular Oxygen Probes
  The Journal of Organic Chemistry. Feb, 2008  |   Pubmed ID: 18201099
• Inactivation of Mitochondrial Respiratory Chain Complex I Leads Mitochondrial Nitric Oxide Synthase to Become Pro-oxidative
  Biochemical and Biophysical Research Communications. Mar, 2008  |   Pubmed ID: 18191636
• Reactivity of Superoxide Anion Radical with a Perchlorotriphenylmethyl (trityl) Radical
  The Journal of Physical Chemistry. B. Jan, 2008  |   Pubmed ID: 18081340
• Large-scale Synthesis of a Persistent Trityl Radical for Use in Biomedical EPR Applications and Imaging
  Bioorganic & Medicinal Chemistry Letters. Dec, 2007  |   Pubmed ID: 17964156
• Rate Constants of Hydroperoxyl Radical Addition to Cyclic Nitrones: a DFT Study
  The Journal of Physical Chemistry. A. Oct, 2007  |   Pubmed ID: 17845014
• Reactivity of Superoxide Radical Anion with Cyclic Nitrones: Role of Intramolecular H-bond and Electrostatic Effects
  Journal of the American Chemical Society. Jul, 2007  |   Pubmed ID: 17564447
• Synthesis and Characterization of a Perchlorotriphenylmethyl (trityl) Triester Radical: a Potential Sensor for Superoxide and Oxygen in Biological Systems
  Bioorganic & Medicinal Chemistry Letters. Jul, 2007  |   Pubmed ID: 17499990
• 4-Aryl-1,3,2-oxathiazolylium-5-olates As PH-controlled NO-donors: the Next Generation of S-nitrosothiols
  Journal of the American Chemical Society. May, 2007  |   Pubmed ID: 17419627
• Theoretical and Experimental Studies of the Spin Trapping of Inorganic Radicals by 5,5-dimethyl-1-pyrroline N-oxide (DMPO). 2. Carbonate Radical Anion
  The Journal of Physical Chemistry. A. Jan, 2007  |   Pubmed ID: 17214476
• Theoretical and Experimental Studies of the Spin Trapping of Inorganic Radicals by 5,5-dimethyl-1-pyrroline N-oxide (DMPO). 1. Carbon Dioxide Radical Anion
  The Journal of Physical Chemistry. A. Dec, 2006  |   Pubmed ID: 17149843
• Reactivity of Molecular Oxygen with Ethoxycarbonyl Derivatives of Tetrathiatriarylmethyl Radicals
  The Journal of Organic Chemistry. Sep, 2006  |   Pubmed ID: 16958520
• Evidence for Increased Exchange Interactions with 5d Compared to 4d Metal Ions. Experimental and Theoretical Insights into the Ferromagnetic Interactions of a Series of Trinuclear [{M(CN)8}3-/NiII] Compounds (M = MoV or WV)
  Journal of the American Chemical Society. Aug, 2006  |   Pubmed ID: 16881650
• Superoxide Radical Anion Adduct of 5,5-dimethyl-1-pyrroline N-oxide (DMPO). 2. The Thermodynamics of Decay and EPR Spectral Properties
  The Journal of Physical Chemistry. A. Jul, 2005  |   Pubmed ID: 16833946
• Superoxide Radical Anion Adduct of 5,5-dimethyl-1-pyrroline N-oxide (DMPO). 1. The Thermodynamics of Formation and Its Acidity
  The Journal of Physical Chemistry. A. Jul, 2005  |   Pubmed ID: 16833945
• Comparative DFT Study of the Spin Trapping of Methyl, Mercapto, Hydroperoxy, Superoxide, and Nitric Oxide Radicals by Various Substituted Cyclic Nitrones
  The Journal of Physical Chemistry. A. Mar, 2005  |   Pubmed ID: 16833491
• Nitric Oxide Release from the Unimolecular Decomposition of the Superoxide Radical Anion Adduct of Cyclic Nitrones in Aqueous Medium
  Organic & Biomolecular Chemistry. Sep, 2005  |   Pubmed ID: 16106305
• Glutathione-mediated Formation of Oxygen Free Radicals by the Major Metabolite of Oltipraz
  Chemical Research in Toxicology. Jun, 2005  |   Pubmed ID: 15962931
• Cancer Chemopreventive Oltipraz Generates Superoxide Anion Radical
  Archives of Biochemistry and Biophysics. Mar, 2005  |   Pubmed ID: 15680910
• Spin Trapping by 5-carbamoyl-5-methyl-1-pyrroline N-oxide (AMPO): Theoretical and Experimental Studies
  The Journal of Organic Chemistry. Nov, 2004  |   Pubmed ID: 15527282
• Detection of Reactive Oxygen and Nitrogen Species by EPR Spin Trapping
  Antioxidants & Redox Signaling. Jun, 2004  |   Pubmed ID: 15130289
• Theoretical Study of the Spin Trapping of Hydroxyl Radical by Cyclic Nitrones: a Density Functional Theory Approach
  Journal of the American Chemical Society. Feb, 2004  |   Pubmed ID: 14871114