Gareth J.S. Jenkins In vitro Toxicology Group Swansea University Medical School Biography Publications Institution JoVE Articles Gareth J.S. Jenkins has not added a biography. If you are Gareth J.S. Jenkins and would like to personalize this page please email our Author Liaison for assistance. Publications Comparison of Passive-dosed and Solvent Spiked Exposures of Pro-carcinogen, Benzo[a]pyrene, to Human Lymphoblastoid Cell Line, MCL-5 Toxicology in Vitro : an International Journal Published in Association with BIBRA. Jun, 2020 | Pubmed ID: 32497684 Nanomaterials and Innate Immunity: A Perspective of the Current Status in Nanosafety Chemical Research in Toxicology. May, 2020 | Pubmed ID: 32307980 Reprint Of: A Three-dimensional in Vitro HepG2 Cells Liver Spheroid Model for Genotoxicity Studies Mutation Research. Genetic Toxicology and Environmental Mutagenesis. Oct, 2018 | Pubmed ID: 30173862 A Three-dimensional in Vitro HepG2 Cells Liver Spheroid Model for Genotoxicity Studies Mutation Research. Genetic Toxicology and Environmental Mutagenesis. Jan, 2018 | Pubmed ID: 29307375 A Novel, Integrated in Vitro Carcinogenicity Test to Identify Genotoxic and Non-genotoxic Carcinogens Using Human Lymphoblastoid Cells Archives of Toxicology. Feb, 2018 | Pubmed ID: 29110037 The Role of Intracellular Trafficking of CdSe/ZnS QDs on Their Consequent Toxicity Profile Journal of Nanobiotechnology. Jun, 2017 | Pubmed ID: 28619032 Critical Review of the Current and Future Challenges Associated with Advanced in Vitro Systems Towards the Study of Nanoparticle (secondary) Genotoxicity Mutagenesis. 01, 2017 | Pubmed ID: 27815329 A Comparison of the Genotoxicity of Benzo[a]pyrene in Four Cell Lines with Differing Metabolic Capacity Mutation Research. Genetic Toxicology and Environmental Mutagenesis. Sep, 2016 | Pubmed ID: 27637481 Genetic Toxicity Assessment of Engineered Nanoparticles Using a 3D in Vitro Skin Model (EpiDerm™) Particle and Fibre Toxicology. 09, 2016 | Pubmed ID: 27613375 Genotoxic Thresholds, DNA Repair, and Susceptibility in Human Populations Toxicology. Dec, 2010 | Pubmed ID: 19932733 The Bile Acid Deoxycholic Acid Has a Non-linear Dose Response for DNA Damage and Possibly NF-kappaB Activation in Oesophageal Cells, with a Mechanism of Action Involving ROS Mutagenesis. Sep, 2008 | Pubmed ID: 18515815 Immunohistochemical Study of Nuclear Factor-kappaB Activity and Interleukin-8 Abundance in Oesophageal Adenocarcinoma; a Useful Strategy for Monitoring These Biomarkers Journal of Clinical Pathology. Nov, 2007 | Pubmed ID: 17220207 Deoxycholic Acid at Neutral and Acid PH, is Genotoxic to Oesophageal Cells Through the Induction of ROS: The Potential Role of Anti-oxidants in Barrett's Oesophagus Carcinogenesis. Jan, 2007 | Pubmed ID: 16905748 The Restriction Site Mutation (RSM) Method: Clinical Applications Mutagenesis. Jan, 2004 | Pubmed ID: 14681308 The Bile Acid Deoxycholic Acid (DCA) at Neutral PH Activates NF-kappaB and Induces IL-8 Expression in Oesophageal Cells in Vitro Carcinogenesis. Mar, 2004 | Pubmed ID: 14656946 Early P53 Mutations in Nondysplastic Barrett's Tissue Detected by the Restriction Site Mutation (RSM) Methodology British Journal of Cancer. Apr, 2003 | Pubmed ID: 12698195 Molecular Analysis of the Chemoprotective Effects of Topical Sunscreen and Vitamin C in Preventing UV-induced and Reactive Oxygen Species-induced DNA Damage, Respectively, Using the PCR Inhibition Methodology Anticancer Research. Nov-Dec, 2002 | Pubmed ID: 12553007 Genetic Pathways Involved in the Progression of Barrett's Metaplasia to Adenocarcinoma The British Journal of Surgery. Jul, 2002 | Pubmed ID: 12081731 Restriction Enzymes in the Analysis of Genetic Alterations Responsible for Cancer Progression The British Journal of Surgery. Jan, 2002 | Pubmed ID: 11851658 The Detection of Mutations Induced in Vitro in the Human P53 Gene by Hydrogen Peroxide with the Restriction Site Mutation (RSM) Assay Mutation Research. Nov, 2001 | Pubmed ID: 11673079 PCR-based Methodology for the Determination of the Photoprotection Afforded by Sunscreen Application BioTechniques. Dec, 2000 | Pubmed ID: 11126135 Restriction Site Mutation (RSM) Analysis of 2-acetylaminofluorene (2-AAF)-induced Mouse Liver Mutations and Comparison with the Measurement of in Vivo Micronucleus Induction in the Bone Marrows of (2-AAF)-treated Mice Teratogenesis, Carcinogenesis, and Mutagenesis. 2000 | Pubmed ID: 10820421 Inverse Restriction Site Mutation (iRSM) Analysis. Mutation Detection Involving the Formation of Restriction Enzyme Sites in Target Genes Mutagenesis. Jan, 1999 | Pubmed ID: 10474819 The Restriction Site Mutation Assay: a Review of the Methodology Development and the Current Status of the Technique Mutagenesis. Sep, 1999 | Pubmed ID: 10473646 A Study of ENU-induced Mutagenesis in the Mouse Using the Restriction Site Mutation (RSM) Assay Teratogenesis, Carcinogenesis, and Mutagenesis. 1999 | Pubmed ID: 10406892 Mutation Analysis Using the Restriction Site Mutation (RSM) Assay Mutation Research. Sep, 1998 | Pubmed ID: 9748583 Investigating FlowSight® Imaging Flow Cytometry As a Platform to Assess Chemically Induced Micronuclei Using Human Lymphoblastoid Cells in Vitro Mutagenesis. | Pubmed ID: 30204902 Advanced 3D Liver Models for In vitro Genotoxicity Testing Following Long-Term Nanomaterial Exposure Samantha V. Llewellyn1, Gillian E. Conway1, Ume-Kulsoom Shah1, Stephen J. Evans1, Gareth J.S. Jenkins1, Martin J.D. Clift1, Shareen H. Doak1 1In vitro Toxicology Group, Swansea University Medical School JoVE 61141 Bioengineering
Advanced 3D Liver Models for In vitro Genotoxicity Testing Following Long-Term Nanomaterial Exposure Samantha V. Llewellyn1, Gillian E. Conway1, Ume-Kulsoom Shah1, Stephen J. Evans1, Gareth J.S. Jenkins1, Martin J.D. Clift1, Shareen H. Doak1 1In vitro Toxicology Group, Swansea University Medical School JoVE 61141 Bioengineering
