Guenther Gastl Internal Medicine V Medical University of Innsbruck Biography Publications Institution JoVE Articles Guenther Gastl has not added a biography. If you are Guenther Gastl and would like to personalize this page please email our Author Liaison for assistance. Publications Treatment of Patients with Refractory Metastatic Cancer According to Molecular Profiling on Tumor Tissue in the Clinical Routine: an Interim-analysis of the ONCO-T-PROFILE Project Genes & Cancer. Sep, 2016 | Pubmed ID: 28050231 Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche Biochimica Et Biophysica Acta. Dec, 2016 | Pubmed ID: 27751894 Long-term Treatment of Hairy Cell Leukemia with Interferon-α: Still A viable Therapeutic Option Memo. 2016 | Pubmed ID: 27429657 High Prevalence of Side Population in Human Cancer Cell Lines Oncoscience. 2016 | Pubmed ID: 27226981 Predominant Expression of Truncated EpCAM is Associated with a More Aggressive Phenotype and Predicts Poor Overall Survival in Colorectal Cancer International Journal of Cancer. Aug, 2016 | Pubmed ID: 26996277 Oncotyrol--Center for Personalized Cancer Medicine: Methods and Applications of Health Technology Assessment and Outcomes Research Zeitschrift Fur Evidenz, Fortbildung Und Qualitat Im Gesundheitswesen. 2015 | Pubmed ID: 26354133 Detection of Soluble EpCAM (sEpCAM) in Malignant Ascites Predicts Poor Overall Survival in Patients Treated with Catumaxomab Oncotarget. Sep, 2015 | Pubmed ID: 26296970 Ropeginterferon Alfa-2b, a Novel IFNα-2b, Induces High Response Rates with Low Toxicity in Patients with Polycythemia Vera Blood. Oct, 2015 | Pubmed ID: 26261238 Drug Transporter-Mediated Protection of Cancer Stem Cells From Ionophore Antibiotics Stem Cells Translational Medicine. Sep, 2015 | Pubmed ID: 26136502 Soluble EpCAM Levels in Ascites Correlate with Positive Cytology and Neutralize Catumaxomab Activity in Vitro BMC Cancer. May, 2015 | Pubmed ID: 25947366 Treg(s) in Cancer: Friends or Foe? Journal of Cellular Physiology. Nov, 2015 | Pubmed ID: 25913194 Marine Compounds Inhibit Growth of Multiple Myeloma in Vitro and in Vivo Oncotarget. Apr, 2015 | Pubmed ID: 25860931 Molecular Responses and Chromosomal Aberrations in Patients with Polycythemia Vera Treated with Peg-proline-interferon Alpha-2b American Journal of Hematology. Apr, 2015 | Pubmed ID: 25545244 (68)Ga-DOTATOC PET/CT Provides Accurate Tumour Extent in Patients with Extraadrenal Paraganglioma Compared to (123)I-MIBG SPECT/CT European Journal of Nuclear Medicine and Molecular Imaging. Jan, 2015 | Pubmed ID: 25134670 The Side Population of Ovarian Cancer Cells Defines a Heterogeneous Compartment Exhibiting Stem Cell Characteristics Oncotarget. Aug, 2014 | Pubmed ID: 25216521 Expression of EpCAM(MF) and EpCAM(MT) Variants in Human Carcinomas Journal of Clinical Pathology. May, 2014 | Pubmed ID: 24465008 Systematic Assessment of Decision-analytic Models for Chronic Myeloid Leukemia Applied Health Economics and Health Policy. Apr, 2014 | Pubmed ID: 24385259 Medical Decision Analysis for First-line Therapy of Chronic Myeloid Leukemia Leukemia & Lymphoma. Aug, 2014 | Pubmed ID: 24160847 Loss of Membranous Expression of the Intracellular Domain of EpCAM is a Frequent Event and Predicts Poor Survival in Patients with Pancreatic Cancer Histopathology. Apr, 2014 | Pubmed ID: 24117877 Transition of Idiopathic CD4 + Lymphocytopenia into Mycosis Fungoides? Leukemia & Lymphoma. Jul, 2014 | Pubmed ID: 24033108 EpCAM Overexpression Prolongs Proliferative Capacity of Primary Human Breast Epithelial Cells and Supports Hyperplastic Growth Molecular Cancer. 2013 | Pubmed ID: 23758908 Phenotype-dependent Effects of EpCAM Expression on Growth and Invasion of Human Breast Cancer Cell Lines BMC Cancer. 2012 | Pubmed ID: 23110550 Low Expression of Junctional Adhesion Molecule A is Associated with Metastasis and Poor Survival in Pancreatic Cancer Annals of Surgical Oncology. Dec, 2012 | Pubmed ID: 22549289 High-dose Imatinib Induction Followed by Standard-dose Maintenance in Pre-treated Chronic Phase Chronic Myeloid Leukemia Patients--final Analysis of a Randomized, Multicenter, Phase III Trial Haematologica. Oct, 2012 | Pubmed ID: 22511495 EpCAM Expression in Primary Tumour Tissues and Metastases: an Immunohistochemical Analysis Journal of Clinical Pathology. May, 2011 | Pubmed ID: 21415054 Clinical Aspects, Diagnostic Challenges and Management of Patients with Neuroendocrine Tumors (NETs) Onkologie. 2011 | Pubmed ID: 21358221 Effects of EpCAM Overexpression on Human Breast Cancer Cell Lines BMC Cancer. 2011 | Pubmed ID: 21281469 High-dose Imatinib Improves Cytogenetic and Molecular Remissions in Patients with Pretreated Philadelphia-positive, BCR-ABL-positive Chronic Phase Chronic Myeloid Leukemia: First Results from the Randomized CELSG Phase III CML 11 "ISTAHIT" Study Haematologica. Jun, 2010 | Pubmed ID: 20145273 GRP-78 Secreted by Tumor Cells Blocks the Antiangiogenic Activity of Bortezomib Blood. Oct, 2009 | Pubmed ID: 19713465 The Sphingosine 1-phosphate Receptor Agonist FTY720 Potently Inhibits Regulatory T Cell Proliferation in Vitro and in Vivo Journal of Immunology (Baltimore, Md. : 1950). Sep, 2009 | Pubmed ID: 19692647 Hodgkin Lymphoma in Tyrol-a Population-based Study Annals of Hematology. May, 2009 | Pubmed ID: 18846373 Possible Role for Gene Expression Profiling in Predicting Responses to Conventional or Targeted Drugs in Patients with Chronic Myeloid Leukemia Leukemia & Lymphoma. Apr, 2008 | Pubmed ID: 18398726 TROP2: a Novel Prognostic Marker in Squamous Cell Carcinoma of the Oral Cavity Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Feb, 2008 | Pubmed ID: 18084248 EpCAM Expression in Squamous Cell Carcinoma of the Oral Cavity: Frequency and Relationship to Clinicopathologic Features Oral Oncology. Jan, 2008 | Pubmed ID: 17418618 Measurement of Cyclin E Genomic Copy Number and Strand Length in Cell-free DNA Distinguish Malignant Versus Benign Effusions Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2007 | Pubmed ID: 17908972 Role of Forkhead Box Protein 3 Expression in Invasive Breast Cancer Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2007 | Pubmed ID: 17906214 Knockdown of PgP Resensitizes Leukemic Cells to Proteasome Inhibitors Biochemical and Biophysical Research Communications. Sep, 2007 | Pubmed ID: 17662692 STAT1 Activation in Squamous Cell Cancer of the Oral Cavity: a Potential Predictive Marker of Response to Adjuvant Chemotherapy Cancer. Jul, 2007 | Pubmed ID: 17559122 Increased Angiogenesis in Chronic Idiopathic Myelofibrosis: Vascular Endothelial Growth Factor As a Prominent Angiogenic Factor Human Pathology. Jul, 2007 | Pubmed ID: 17442379 High EGFR Expression Predicts Poor Prognosis in Patients with Squamous Cell Carcinoma of the Oral Cavity and Oropharynx: a TMA-based Immunohistochemical Analysis Oral Oncology. Feb, 2007 | Pubmed ID: 16854613 Methylierung Status Des Gebietes Projektträger Ep-CAM in Der Menschlichen Brust-Krebs-Zelllinien Und Krebs Brustgewebe Cancer Letters. Feb, 2007 | Pubmed ID: 16624485 The Effect of Zoledronic Acid on the Function and Differentiation of Myeloid Cells Haematologica. Sep, 2006 | Pubmed ID: 16956814 Synergistic and Additive Antiproliferative Effects on Human Leukemia Cell Lines Induced by Combining Acetylenehexacarbonyldicobalt Complexes with the Tyrosine Kinase Inhibitor Imatinib Journal of Inorganic Biochemistry. Nov, 2006 | Pubmed ID: 16908070 Overexpression of Epithelial Cell Adhesion Molecule (Ep-CAM) is an Independent Prognostic Marker for Reduced Survival of Patients with Epithelial Ovarian Cancer Gynecologic Oncology. Nov, 2006 | Pubmed ID: 16678891 Telomere Length of in Vivo Expanded CD4(+)CD25 (+) Regulatory T-cells is Preserved in Cancer Patients Cancer Immunology, Immunotherapy : CII. Oct, 2006 | Pubmed ID: 16362412 The Expression of the Regulatory T Cell-specific Forkhead Box Transcription Factor FoxP3 is Associated with Poor Prognosis in Ovarian Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2005 | Pubmed ID: 16322292 The Kinase Inhibitor Imatinib Mesylate Inhibits TNF-{alpha} Production in Vitro and Prevents TNF-dependent Acute Hepatic Inflammation Proceedings of the National Academy of Sciences of the United States of America. Sep, 2005 | Pubmed ID: 16174751 Dendritic Cells from Patients with Chronic Myeloid Leukemia: Functional and Phenotypic Features Leukemia & Lymphoma. May, 2005 | Pubmed ID: 16019503 RNAi-mediated Knockdown of P-glycoprotein Using a Transposon-based Vector System Durably Restores Imatinib Sensitivity in Imatinib-resistant CML Cell Lines Experimental Hematology. Jul, 2005 | Pubmed ID: 15963852 Ovarialkarzinom Zellen Und IL-1beta-aktivierten Humanen Peritoneale Mesothelzellen Sind Mögliche Quellen Des Vaskulären Endothelialen Wachstumsfaktors Bei Entzündlichen Und Malignen Peritoneale Ergüsse Gynecologic Oncology. Jun, 2005 | Pubmed ID: 15943987 Hodgkin's Disease Variant of Richter's Syndrome in Chronic Lymphocytic Leukaemia Patients Previously Treated with Fludarabine British Journal of Haematology. Apr, 2005 | Pubmed ID: 15813847 CD4+CD25+ Regulatory T Cells Inhibit Experimental Anti-glomerular Basement Membrane Glomerulonephritis in Mice Journal of the American Society of Nephrology : JASN. May, 2005 | Pubmed ID: 15788479 High Ep-CAM Expression is Associated with Poor Prognosis in Node-positive Breast Cancer Breast Cancer Research and Treatment. Aug, 2004 | Pubmed ID: 15567937 Anagrelide for Thrombocytosis in Myeloproliferative Disorders: a Prospective Study to Assess Efficacy and Adverse Event Profile Cancer. Nov, 2004 | Pubmed ID: 15476273 Overexpression of Epithelial Cell Adhesion Molecule Antigen in Gallbladder Carcinoma is an Independent Marker for Poor Survival Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2004 | Pubmed ID: 15131054 Progressive Multifocal Leukoencephalopathy After Allogeneic Stem Cell Transplantation and Posttransplantation Rituximab Transplantation. Jul, 2003 | Pubmed ID: 12883208 Increase of Regulatory T Cells in the Peripheral Blood of Cancer Patients Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2003 | Pubmed ID: 12576425 Phenotypic and Functional Deficiencies of Leukaemic Dendritic Cells from Patients with Chronic Myeloid Leukaemia British Journal of Haematology. Jan, 2003 | Pubmed ID: 12492578 Low Concentrations of STI571 in the Cerebrospinal Fluid: a Case Report British Journal of Haematology. Jun, 2002 | Pubmed ID: 12028032 Hepatosplenic Gammadelta-T-cell Lymphoma with Leukemic Course After Renal Transplantation Human Pathology. Feb, 2002 | Pubmed ID: 11957154 Die DNA-Farbstoff-ausgelöste Seitenbevölkerung Phänotyp zur Erkennung und Reinigung von Krebsstammzellen aus biologischen Proben Maximilian Boesch*1,2,3, Elisabeth Hoflehner2,3, Dominik Wolf2,3,4, Guenther Gastl2, Sieghart Sopper*2,3 1Institute of Immunobiology, Kantonsspital St. Gallen, 2Internal Medicine V, Medical University of Innsbruck, 3Tyrolean Cancer Research Institute (TKFI), 4Medical Clinic III, Oncology, Hematology, Immunoncology and Rheumatology, University Clinic Bonn (UKB) JoVE 55634 Cancer Research
Die DNA-Farbstoff-ausgelöste Seitenbevölkerung Phänotyp zur Erkennung und Reinigung von Krebsstammzellen aus biologischen Proben Maximilian Boesch*1,2,3, Elisabeth Hoflehner2,3, Dominik Wolf2,3,4, Guenther Gastl2, Sieghart Sopper*2,3 1Institute of Immunobiology, Kantonsspital St. Gallen, 2Internal Medicine V, Medical University of Innsbruck, 3Tyrolean Cancer Research Institute (TKFI), 4Medical Clinic III, Oncology, Hematology, Immunoncology and Rheumatology, University Clinic Bonn (UKB) JoVE 55634 Cancer Research
