Heike Walles Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik (IGB), Translationszentrum Würzburg 'Regenerative Therapien für Krebs- und Muskuloskelettale Erkrankung' Institutsteil Würzburg Biography Publications Institution JoVE Articles Heike Walles has not added a biography. If you are Heike Walles and would like to personalize this page please email our Author Liaison for assistance. Publications Advanced Therapy Medicinal Products: A Guide for Bone Marrow-derived MSC Application in Bone and Cartilage Tissue Engineering Tissue Engineering. Part B, Reviews. Dec, 2017 | Pubmed ID: 28990462 Calcium Fluoride Based Multifunctional Nanoparticles for Multimodal Imaging Beilstein Journal of Nanotechnology. 2017 | Pubmed ID: 28900602 Preparation of a Three-Dimensional Full Thickness Skin Equivalent Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 28634944 A Comparative Multi-parametric in Vitro Model Identifies the Power of Test Conditions to Predict the Fibrotic Tendency of a Biomaterial Scientific Reports. May, 2017 | Pubmed ID: 28490729 * An Injectable Recombinant Collagen I Peptide-Based Macroporous Microcarrier Allows Superior Expansion of C2C12 and Human Bone Marrow-Derived Mesenchymal Stromal Cells and Supports Deposition of Mineralized Matrix Tissue Engineering. Part A. Sep, 2017 | Pubmed ID: 28437178 Osteogenesis and Mineralization of Mesenchymal Stem Cells in Collagen Type I-based Recombinant Peptide Scaffolds Journal of Biomedical Materials Research. Part A. Jul, 2017 | Pubmed ID: 28247927 Three-Dimensional Coculture of Meniscal Cells and Mesenchymal Stem Cells in Collagen Type I Hydrogel on a Small Intestinal Matrix-A Pilot Study Toward Equine Meniscus Tissue Engineering Tissue Engineering. Part A. May, 2017 | Pubmed ID: 28095754 Ex Vivo Culture Platform for Assessment of Cartilage Repair Treatment Strategies ALTEX. 2017 | Pubmed ID: 27768805 In Vitro Chemotaxis and Tissue Remodeling Assays Quantitatively Characterize Foreign Body Reaction ALTEX. 2017 | Pubmed ID: 27725990 Human Barrier Models for the in Vitro Assessment of Drug Delivery Drug Delivery and Translational Research. Apr, 2017 | Pubmed ID: 27549106 A Versatile Modular Bioreactor Platform for Tissue Engineering Biotechnology Journal. Feb, 2017 | Pubmed ID: 27492568 Non-Coding RNAs in Lung Cancer: Contribution of Bioinformatics Analysis to the Development of Non-Invasive Diagnostic Tools Genes. Dec, 2016 | Pubmed ID: 28035947 Human Organotypic Lung Tumor Models: Suitable For Preclinical 18F-FDG PET-Imaging PloS One. 2016 | Pubmed ID: 27501455 Catch-up Validation Study of an in Vitro Skin Irritation Test Method Based on an Open Source Reconstructed Epidermis (phase II) Toxicology in Vitro : an International Journal Published in Association with BIBRA. Oct, 2016 | Pubmed ID: 27435616 Feasibility Study on a Microwave-Based Sensor for Measuring Hydration Level Using Human Skin Models PloS One. 2016 | Pubmed ID: 27046226 Activation of Myenteric Glia During Acute Inflammation In Vitro and In Vivo PloS One. 2016 | Pubmed ID: 26964064 Differential Regulation of SOX9 Protein During Chondrogenesis of Induced Pluripotent Stem Cells Versus Mesenchymal Stromal Cells: A Shortcoming for Cartilage Formation Stem Cells and Development. Mar, 2016 | Pubmed ID: 26906619 Alternative Methods for the Replacement of Eye Irritation Testing ALTEX. 2016 | Pubmed ID: 26626125 Non-animal Models of Epithelial Barriers (skin, Intestine and Lung) in Research, Industrial Applications and Regulatory Toxicology ALTEX. 2015 | Pubmed ID: 26536291 Applicability of Second-generation Upcyte® Human Hepatocytes for Use in CYP Inhibition and Induction Studies Pharmacology Research & Perspectives. Oct, 2015 | Pubmed ID: 26516577 In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells PloS One. 2015 | Pubmed ID: 26488607 A Perfusion Bioreactor System Efficiently Generates Cell-loaded Bone Substitute Materials for Addressing Critical Size Bone Defects Biotechnology Journal. Sep, 2015 | Pubmed ID: 26011163 Host-integration of a Tissue-engineered Airway Patch: Two-year Follow-up in a Single Patient Tissue Engineering. Part A. Feb, 2015 | Pubmed ID: 25316325 An Engineered 3D Human Airway Mucosa Model Based on an SIS Scaffold Biomaterials. Aug, 2014 | Pubmed ID: 24912816 Establishment of a Human 3D Lung Cancer Model Based on a Biological Tissue Matrix Combined with a Boolean in Silico Model Molecular Oncology. Mar, 2014 | Pubmed ID: 24388494 A Human in Vitro Model That Mimics the Renal Proximal Tubule Tissue Engineering. Part C, Methods. Jul, 2014 | Pubmed ID: 24266327 Integrating Biological Vasculature into a Multi-organ-chip Microsystem Lab on a Chip. Sep, 2013 | Pubmed ID: 23743770 Bone Tissue Engineering in Osteoporosis Maturitas. Jun, 2013 | Pubmed ID: 23562167 Strategies in Tissue Engineering and Regenerative Medicine Biotechnology Journal. Mar, 2013 | Pubmed ID: 23460549 Bioreactors in Tissue Engineering - Principles, Applications and Commercial Constraints Biotechnology Journal. Mar, 2013 | Pubmed ID: 23161827 Ammonia Plasma Treatment of Polystyrene Surfaces Enhances Proliferation of Primary Human Mesenchymal Stem Cells and Human Endothelial Cells Biotechnology Journal. Mar, 2013 | Pubmed ID: 23070995 A Bioreactor System for Interfacial Culture and Physiological Perfusion of Vascularized Tissue Equivalents Biotechnology Journal. Mar, 2013 | Pubmed ID: 23047238 Upcyte® Microvascular Endothelial Cells Repopulate Decellularized Scaffold Tissue Engineering. Part C, Methods. Jan, 2013 | Pubmed ID: 22799502 'Human-on-a-chip' Developments: a Translational Cutting-edge Alternative to Systemic Safety Assessment and Efficiency Evaluation of Substances in Laboratory Animals and Man? Alternatives to Laboratory Animals : ATLA. Oct, 2012 | Pubmed ID: 23215661 Oligonucleotide and Parylene Surface Coating of Polystyrene and EPTFE for Improved Endothelial Cell Attachment and Hemocompatibility International Journal of Biomaterials. 2012 | Pubmed ID: 22481939 Terapie Rigenerative Basate Su Cellule Staminali E Fattore Di Crescita Per Necrosi Avascolare Della Testa Femorale Stem Cell Research & Therapy. 2012 | Pubmed ID: 22356811 In Situ Guided Tissue Regeneration in Musculoskeletal Diseases and Aging : Implementing Pathology into Tailored Tissue Engineering Strategies Cell and Tissue Research. Mar, 2012 | Pubmed ID: 22011785 Raman Spectroscopy for the Non-contact and Non-destructive Monitoring of Collagen Damage Within Tissues Journal of Biophotonics. Jan, 2012 | Pubmed ID: 21954177 Raman Spectroscopy: a Noninvasive Analysis Tool for the Discrimination of Human Skin Cells Tissue Engineering. Part C, Methods. Oct, 2011 | Pubmed ID: 21774693 The Physiological Performance of a Three-dimensional Model That Mimics the Microenvironment of the Small Intestine Biomaterials. Oct, 2011 | Pubmed ID: 21764120 Stem Cell Microenvironments--unveiling the Secret of How Stem Cell Fate is Defined Macromolecular Bioscience. Nov, 2010 | Pubmed ID: 20715131 Elettrofilate Poly(D/L-lactide-co-L-lactide) Matrice Ibrida: Un Materiale Romanzo Impalcatura Per L'ingegneria Dei Tessuti Molli Journal of Materials Science. Materials in Medicine. Sep, 2010 | Pubmed ID: 20640490 Raman Spectroscopy As a Tool for Quality and Sterility Analysis for Tissue Engineering Applications Like Cartilage Transplants The International Journal of Artificial Organs. Apr, 2010 | Pubmed ID: 20458692 Vascularised Human Tissue Models: a New Approach for the Refinement of Biomedical Research Journal of Biotechnology. Jul, 2010 | Pubmed ID: 20399817 Site-Directed immobilizzazione della proteina morfogenetica ossea 2 a superfici solide di Click Chemistry Claudia Siverino1, Barbara Tabisz2, Tessa Lühmann3, Lorenz Meinel3, Thomas Müller4, Heike Walles1,2, Joachim Nickel1,2 1Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik (IGB), Translationszentrum Würzburg 'Regenerative Therapien für Krebs- und Muskuloskelettale Erkrankung', Institutsteil Würzburg, 2Lehrstuhl für Tissue Engineering und Regenerative Medizin, Universitätsklinikum Würzburg, 3Lehrstuhl für Pharmazeutische Technologie und Biopharmazie, Universität Würzburg, 4Lehrstuhl für molekulare Pflanzenphysiologie und Biophysik, Julius-von-Sachs Institut für Biowissenschaften, Universität Würzburg JoVE 56616 Bioengineering Ricombinante collagene Peptide Microcarriers per l'espansione delle cellule e loro potenziale utilizzo come sistema di consegna di cella in un bioreattore modello Melva Suarez Muñoz1, Davide Confalonieri1, Heike Walles1,2, Elisabeth M. W. M. van Dongen3, Gudrun Dandekar1,2 1Department Tissue Engineering and Regenerative Medicine, University Hospital Wuerzburg, 2Translational Center Regenerative Therapies (TLC-RT), Fraunhofer Institute for Silicate Research ISC, 3Fujifilm Manufacturing Europe B.V. JoVE 57363 Bioengineering Un Tessuto 3D combinata Engineered Claudia Göttlich*1, Lena C. Müller*1, Meik Kunz*3, Franziska Schmitt1, Heike Walles1,4, Thorsten Walles2, Thomas Dandekar3, Gudrun Dandekar1,4, Sarah L. Nietzer1 1Department of Tissue Engineering and Regenerative Medicine (TERM), University Hospital Wuerzburg, 2Department of Cardiothoracic Surgery, University Hospital Wuerzburg, 3Department of Bioinformatics, University Wuerzburg, 4Translational Center Wuerzburg, Fraunhofer Institute Interfacial Engineering and Biotechnology IGB Bioengineering Generazione di una tridimensionale a tutto spessore della pelle Equivalent e Automated Ferimento Angela Rossi*1, Antje Appelt-Menzel*1, Szymon Kurdyn1, Heike Walles1,2, Florian Groeber2 1Department for Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, 2Translational Center Würzburg, Regenerative Therapies in Oncology and Musculoskelettal Disease, Würzburg Branch of the Fraunhofer-Institute Interfacial Engineering and Biotechnology, IGB Bioengineering Ingegneria dei tessuti di un Umano 3D Corinna Moll*1, Jenny Reboredo*1, Thomas Schwarz1, Antje Appelt1, Sebastian Schürlein1, Heike Walles1, Sarah Nietzer1 1Department of Tissue Engineering and Regenerative Medicine, University Hospital Würzburg JoVE 50460 Bioengineering Senza contatto, Label-free monitoraggio delle cellule e matrice extracellulare mediante Spettroscopia Raman Miriam Votteler1,2, Daniel A. Carvajal Berrio2, Marieke Pudlas2,3, Heike Walles2,4, Katja Schenke-Layland1,2 1Department of Thoracic and Cardiovascular Surgery and Inter-University Centre for Medical Technology Stuttgart-Tübingen (IZST), Eberhard Karls University, Tübingen, 2Department of Cell and Tissue Engineering, Fraunhofer Institute of Interfacial Engineering and Biotechnology (IGB) Stuttgart, Germany, 3Department for Medical Interfacial Engineering (IGVT), University of Stuttgart, Germany, 4Institute of Tissue Engineering and Regenerative Medicine, Julius-Maximillians University, Würzburg, Germany JoVE 3977 Bioengineering
Site-Directed immobilizzazione della proteina morfogenetica ossea 2 a superfici solide di Click Chemistry Claudia Siverino1, Barbara Tabisz2, Tessa Lühmann3, Lorenz Meinel3, Thomas Müller4, Heike Walles1,2, Joachim Nickel1,2 1Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik (IGB), Translationszentrum Würzburg 'Regenerative Therapien für Krebs- und Muskuloskelettale Erkrankung', Institutsteil Würzburg, 2Lehrstuhl für Tissue Engineering und Regenerative Medizin, Universitätsklinikum Würzburg, 3Lehrstuhl für Pharmazeutische Technologie und Biopharmazie, Universität Würzburg, 4Lehrstuhl für molekulare Pflanzenphysiologie und Biophysik, Julius-von-Sachs Institut für Biowissenschaften, Universität Würzburg JoVE 56616 Bioengineering
Ricombinante collagene Peptide Microcarriers per l'espansione delle cellule e loro potenziale utilizzo come sistema di consegna di cella in un bioreattore modello Melva Suarez Muñoz1, Davide Confalonieri1, Heike Walles1,2, Elisabeth M. W. M. van Dongen3, Gudrun Dandekar1,2 1Department Tissue Engineering and Regenerative Medicine, University Hospital Wuerzburg, 2Translational Center Regenerative Therapies (TLC-RT), Fraunhofer Institute for Silicate Research ISC, 3Fujifilm Manufacturing Europe B.V. JoVE 57363 Bioengineering
Un Tessuto 3D combinata Engineered Claudia Göttlich*1, Lena C. Müller*1, Meik Kunz*3, Franziska Schmitt1, Heike Walles1,4, Thorsten Walles2, Thomas Dandekar3, Gudrun Dandekar1,4, Sarah L. Nietzer1 1Department of Tissue Engineering and Regenerative Medicine (TERM), University Hospital Wuerzburg, 2Department of Cardiothoracic Surgery, University Hospital Wuerzburg, 3Department of Bioinformatics, University Wuerzburg, 4Translational Center Wuerzburg, Fraunhofer Institute Interfacial Engineering and Biotechnology IGB Bioengineering
Generazione di una tridimensionale a tutto spessore della pelle Equivalent e Automated Ferimento Angela Rossi*1, Antje Appelt-Menzel*1, Szymon Kurdyn1, Heike Walles1,2, Florian Groeber2 1Department for Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, 2Translational Center Würzburg, Regenerative Therapies in Oncology and Musculoskelettal Disease, Würzburg Branch of the Fraunhofer-Institute Interfacial Engineering and Biotechnology, IGB Bioengineering
Ingegneria dei tessuti di un Umano 3D Corinna Moll*1, Jenny Reboredo*1, Thomas Schwarz1, Antje Appelt1, Sebastian Schürlein1, Heike Walles1, Sarah Nietzer1 1Department of Tissue Engineering and Regenerative Medicine, University Hospital Würzburg JoVE 50460 Bioengineering
Senza contatto, Label-free monitoraggio delle cellule e matrice extracellulare mediante Spettroscopia Raman Miriam Votteler1,2, Daniel A. Carvajal Berrio2, Marieke Pudlas2,3, Heike Walles2,4, Katja Schenke-Layland1,2 1Department of Thoracic and Cardiovascular Surgery and Inter-University Centre for Medical Technology Stuttgart-Tübingen (IZST), Eberhard Karls University, Tübingen, 2Department of Cell and Tissue Engineering, Fraunhofer Institute of Interfacial Engineering and Biotechnology (IGB) Stuttgart, Germany, 3Department for Medical Interfacial Engineering (IGVT), University of Stuttgart, Germany, 4Institute of Tissue Engineering and Regenerative Medicine, Julius-Maximillians University, Würzburg, Germany JoVE 3977 Bioengineering
