Hu Shengquan Department of Applied Biology and Chemistry Technology, Institute of Modern Chinese Medicine The Hong Kong Polytechnic University Biography Publications Institution JoVE Articles Hu Shengquan has not added a biography. If you are Hu Shengquan and would like to personalize this page please email our Author Liaison for assistance. Publications Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis Via Concurrently Inhibiting GSK3β and the ERK Pathway Cellular and Molecular Neurobiology. May, 2017 | Pubmed ID: 27412761 Neuroprotection Against Glutamate-induced Excitotoxicity and Induction of Neurite Outgrowth by T-006, a Novel Multifunctional Derivative of Tetramethylpyrazine in Neuronal Cell Models Neurochemistry International. Oct, 2016 | Pubmed ID: 27445088 Potent Protection Against MPP(+)-Induced Neurotoxicity Via Activating Transcription Factor MEF2D by a Novel Derivative of Naturally Occurring Danshensu/Tetramethylpyrazine Neuromolecular Medicine. Dec, 2016 | Pubmed ID: 27277280 Sunitinib, a Clinically Used Anticancer Drug, Is a Potent AChE Inhibitor and Attenuates Cognitive Impairments in Mice ACS Chemical Neuroscience. Aug, 2016 | Pubmed ID: 27046396 Tanshinone II A, a Multiple Target Neuroprotectant, Promotes Caveolae-dependent Neuronal Differentiation European Journal of Pharmacology. Oct, 2015 | Pubmed ID: 26363255 Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells Via Activating MEF2D Through the Inhibition of GSK3β Journal of Molecular Neuroscience : MN. Dec, 2015 | Pubmed ID: 26346600 Protection Against β-amyloid-induced Synaptic and Memory Impairments Via Altering β-amyloid Assembly by Bis(heptyl)-cognitin Scientific Reports. Jul, 2015 | Pubmed ID: 26194093 Substantial Neuroprotective and Neurite Outgrowth-Promoting Activities by Bis(propyl)-cognitin Via the Activation of Alpha7-nAChR, a Promising Anti-Alzheimer's Dimer ACS Chemical Neuroscience. Sep, 2015 | Pubmed ID: 26147504 Inhibiting β-amyloid-associated Alzheimer's Pathogenesis in Vitro and in Vivo by a Multifunctional Dimeric Bis(12)-hupyridone Derived from Its Natural Analogue Journal of Molecular Neuroscience : MN. Apr, 2015 | Pubmed ID: 25407821 Synergistic Inhibition on Acetylcholinesterase by the Combination of Berberine and Palmatine Originally Isolated from Chinese Medicinal Herbs Journal of Molecular Neuroscience : MN. Jul, 2014 | Pubmed ID: 24793543 Bis(propyl)-cognitin Protects Against Glutamate-induced Neuro-excitotoxicity Via Concurrent Regulation of NO, MAPK/ERK and PI3-K/Akt/GSK3β Pathways Neurochemistry International. Mar, 2013 | Pubmed ID: 23357479 Bis(12)-hupyridone, a Novel Acetylcholinesterase Inhibitor, Protects Against Glutamate-induced Neuronal Excitotoxicity Via Activating α7 Nicotinic Acetylcholine Receptor/phosphoinositide 3-kinase/Akt Cascade Chemico-biological Interactions. Mar, 2013 | Pubmed ID: 23085120 The Anti-cancer Agent SU4312 Unexpectedly Protects Against MPP(+) -induced Neurotoxicity Via Selective and Direct Inhibition of Neuronal NOS British Journal of Pharmacology. Mar, 2013 | Pubmed ID: 23062100 Unexpected Neuronal Protection of SU5416 Against 1-Methyl-4-phenylpyridinium Ion-induced Toxicity Via Inhibiting Neuronal Nitric Oxide Synthase PloS One. 2012 | Pubmed ID: 23049997 Tacrine(2)-ferulic Acid, a Novel Multifunctional Dimer, Attenuates 6-hydroxydopamine-induced Apoptosis in PC12 Cells by Activating Akt Pathway Neurochemistry International. Dec, 2011 | Pubmed ID: 21939707 PI3-K/Akt and ERK Pathways Activated by VEGF Play Opposite Roles in MPP+-induced Neuronal Apoptosis Neurochemistry International. Nov, 2011 | Pubmed ID: 21781996 Bis(12)-hupyridone, a Novel Multifunctional Dimer, Promotes Neuronal Differentiation More Potently Than Its Monomeric Natural Analog Huperzine A Possibly Through α7 NAChR Brain Research. Jul, 2011 | Pubmed ID: 21665194 Protection Against 1-methyl-4-phenylpyridinium Ion (MPP+)-induced Apoptosis by Water Extract of Ginseng (Panax Ginseng C.A. Meyer) in SH-SY5Y Cells Journal of Ethnopharmacology. Apr, 2011 | Pubmed ID: 21349320 使用荧光素二乙酸酯 - 碘化丙啶双重染色在小脑颗粒神经元培养中评估神经元活力 Lin Jiajia*1, Mak Shinghung*2, Zheng Jiacheng1, Wang Jialing1, Xu Dilin1, Hu Shengquan2, Zhang Zaijun3, Wang Qinwen1, Han Yifan2,4, Cui Wei1,2 1Ningbo Key Laboratory of Behavioral Neuroscience, Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, 2Department of Applied Biology and Chemistry Technology, Institute of Modern Chinese Medicine, The Hong Kong Polytechnic University, 3Institute of New Drug Research, Guangdong Provincial Key Laboratory of Pharmacodynamic, Constituents of Traditional Chinese Medicine & New Drug Research, College of Pharmacy, Jinan University, 4International Joint Laboratory (SYSU-PolyU HK) of Novel Anti-Dementia Drugs of Guangdong JoVE 55442 Neuroscience
使用荧光素二乙酸酯 - 碘化丙啶双重染色在小脑颗粒神经元培养中评估神经元活力 Lin Jiajia*1, Mak Shinghung*2, Zheng Jiacheng1, Wang Jialing1, Xu Dilin1, Hu Shengquan2, Zhang Zaijun3, Wang Qinwen1, Han Yifan2,4, Cui Wei1,2 1Ningbo Key Laboratory of Behavioral Neuroscience, Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, 2Department of Applied Biology and Chemistry Technology, Institute of Modern Chinese Medicine, The Hong Kong Polytechnic University, 3Institute of New Drug Research, Guangdong Provincial Key Laboratory of Pharmacodynamic, Constituents of Traditional Chinese Medicine & New Drug Research, College of Pharmacy, Jinan University, 4International Joint Laboratory (SYSU-PolyU HK) of Novel Anti-Dementia Drugs of Guangdong JoVE 55442 Neuroscience
