Isabel Fariñas

Publications

• Regulation of the P19(Arf)/p53 Pathway by Histone Acetylation Underlies Neural Stem Cell Behavior in Senescence-prone SAMP8 Mice
  Aging Cell. Jun, 2015  |   Pubmed ID: 25728253
• The Cyclin-dependent Kinase Inhibitor P27 Kip1 Regulates Radial Stem Cell Quiescence and Neurogenesis in the Adult Hippocampus
  Stem Cells (Dayton, Ohio). Jan, 2015  |   Pubmed ID: 25185890
• Endothelial NT-3 Delivered by Vasculature and CSF Promotes Quiescence of Subependymal Neural Stem Cells Through Nitric Oxide Induction
  Neuron. Aug, 2014  |   Pubmed ID: 25043422
• MT5-MMP Regulates Adult Neural Stem Cell Functional Quiescence Through the Cleavage of N-cadherin
  Nature Cell Biology. Jul, 2014  |   Pubmed ID: 24952463
• Lewy Body Extracts from Parkinson Disease Brains Trigger α-synuclein Pathology and Neurodegeneration in Mice and Monkeys
  Annals of Neurology. Mar, 2014  |   Pubmed ID: 24243558
• The APC/C Cofactor Cdh1 Prevents Replicative Stress and P53-dependent Cell Death in Neural Progenitors
  Nature Communications. 2013  |   Pubmed ID: 24301385
• Transcriptional Repression of Bmp2 by P21(Waf1/Cip1) Links Quiescence to Neural Stem Cell Maintenance
  Nature Neuroscience. Nov, 2013  |   Pubmed ID: 24097040
• Cyclin-dependent Kinase Inhibitor P21 Controls Adult Neural Stem Cell Expansion by Regulating Sox2 Gene Expression
  Cell Stem Cell. Jan, 2013  |   Pubmed ID: 23260487
• Symmetric Expansion of Neural Stem Cells from the Adult Olfactory Bulb is Driven by Astrocytes Via WNT7A
  Stem Cells (Dayton, Ohio). Dec, 2012  |   Pubmed ID: 22987443
• IRS2 Signalling is Required for the Development of a Subset of Sensory Spinal Neurons
  The European Journal of Neuroscience. Feb, 2012  |   Pubmed ID: 22288475
• Postnatal Loss of Dlk1 Imprinting in Stem Cells and Niche Astrocytes Regulates Neurogenesis
  Nature. Jul, 2011  |   Pubmed ID: 21776083
• Regulated Segregation of Kinase Dyrk1A During Asymmetric Neural Stem Cell Division is Critical for EGFR-mediated Biased Signaling
  Cell Stem Cell. Sep, 2010  |   Pubmed ID: 20804972
• Signaling Through BMPR-IA Regulates Quiescence and Long-term Activity of Neural Stem Cells in the Adult Hippocampus
  Cell Stem Cell. Jul, 2010  |   Pubmed ID: 20621052
• Perivascular Nerve Fiber α-synuclein Regulates Contractility of Mouse Aorta: a Link to Autonomic Dysfunction in Parkinson's Disease
  Neurochemistry International. Jul, 2010  |   Pubmed ID: 20420875
• Vulnerability of Peripheral Catecholaminergic Neurons to MPTP is Not Regulated by Alpha-synuclein
  Neurobiology of Disease. Apr, 2010  |   Pubmed ID: 20079841
• BDNF is Essentially Required for the Early Postnatal Survival of Nociceptors
  Developmental Biology. Mar, 2010  |   Pubmed ID: 20067784
• Ikaros-1 Couples Cell Cycle Arrest of Late Striatal Precursors with Neurogenesis of Enkephalinergic Neurons
  The Journal of Comparative Neurology. Feb, 2010  |   Pubmed ID: 19950118
• Telomere Shortening in Neural Stem Cells Disrupts Neuronal Differentiation and Neuritogenesis
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2009  |   Pubmed ID: 19923274
• Glial Precursors Clear Sensory Neuron Corpses During Development Via Jedi-1, an Engulfment Receptor
  Nature Neuroscience. Dec, 2009  |   Pubmed ID: 19915564
• Vascular Niche Factor PEDF Modulates Notch-dependent Stemness in the Adult Subependymal Zone
  Nature Neuroscience. Dec, 2009  |   Pubmed ID: 19898467
• Metalloproteinase MT5-MMP is an Essential Modulator of Neuro-immune Interactions in Thermal Pain Stimulation
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2009  |   Pubmed ID: 19805319
• Satb2 Regulates Callosal Projection Neuron Identity in the Developing Cerebral Cortex
  Neuron. Feb, 2008  |   Pubmed ID: 18255030
• Cell Expression of GDAP1 in the Nervous System and Pathogenesis of Charcot-Marie-Tooth Type 4A Disease
  Journal of Cellular and Molecular Medicine. Apr, 2008  |   Pubmed ID: 18021315
• A Combined Ex/in Vivo Assay to Detect Effects of Exogenously Added Factors in Neural Stem Cells
  Nature Protocols. 2007  |   Pubmed ID: 17474182
• SATB2 is a Multifunctional Determinant of Craniofacial Patterning and Osteoblast Differentiation
  Cell. Jun, 2006  |   Pubmed ID: 16751105
• Pigment Epithelium-derived Factor is a Niche Signal for Neural Stem Cell Renewal
  Nature Neuroscience. Mar, 2006  |   Pubmed ID: 16491078
• Selective Glial Cell Line-derived Neurotrophic Factor Production in Adult Dopaminergic Carotid Body Cells in Situ and After Intrastriatal Transplantation
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2005  |   Pubmed ID: 15843611
• BDNF, but Not NT-4, is Necessary for Normal Development of Meissner Corpuscles
  Neuroscience Letters. Mar, 2005  |   Pubmed ID: 15722178
• Stressor-related Impairment of Synaptic Transmission in Hippocampal Slices from Alpha-synuclein Knockout Mice
  The European Journal of Neuroscience. Dec, 2004  |   Pubmed ID: 15579163
• Alpha-Synuclein Expression Levels Do Not Significantly Affect Proteasome Function and Expression in Mice and Stably Transfected PC12 Cell Lines
  The Journal of Biological Chemistry. Dec, 2004  |   Pubmed ID: 15466467
• Telomere Shortening and Chromosomal Instability Abrogates Proliferation of Adult but Not Embryonic Neural Stem Cells
  Development (Cambridge, England). Aug, 2004  |   Pubmed ID: 15269166
• Erbb2 Regulates Neuromuscular Synapse Formation and is Essential for Muscle Spindle Development
  Development (Cambridge, England). Jun, 2003  |   Pubmed ID: 12702645
• Regulation of Neurogenesis by Neurotrophins in Developing Spinal Sensory Ganglia
  Brain Research Bulletin. Apr, 2002  |   Pubmed ID: 12031277