Jamal Tazi

Publications

• Antagonistic Functions of LMNA Isoforms in Energy Expenditure and Lifespan
  EMBO Reports. May, 2014  |   Pubmed ID: 24639560
• MBNL1 and RBFOX2 Cooperate to Establish a Splicing Programme Involved in Pluripotent Stem Cell Differentiation
  Nature Communications. 2013  |   Pubmed ID: 24048253
• The Sirtuin SIRT6 Regulates Stress Granule Formation in C. Elegans and Mammals
  Journal of Cell Science. Nov, 2013  |   Pubmed ID: 24013546
• Tissue-specific and SRSF1-dependent Splicing of Fibronectin, a Matrix Protein That Controls Host Cell Invasion
  Molecular Biology of the Cell. Oct, 2013  |   Pubmed ID: 23966470
• Deficiency of G3BP1, the Stress Granules Assembly Factor, Results in Abnormal Synaptic Plasticity and Calcium Homeostasis in Neurons
  Journal of Neurochemistry. Feb, 2013  |   Pubmed ID: 23373770
• RBFOX2 is an Important Regulator of Mesenchymal Tissue-specific Splicing in Both Normal and Cancer Tissues
  Molecular and Cellular Biology. Jan, 2013  |   Pubmed ID: 23149937
• Regulated Functional Alternative Splicing in Drosophila
  Nucleic Acids Research. Jan, 2012  |   Pubmed ID: 21908400
• Tissue-specific Alternative Splicing of Tak1 is Conserved in Deuterostomes
  Molecular Biology and Evolution. Jan, 2012  |   Pubmed ID: 21873631
• Revisiting G3BP1 As a RasGAP Binding Protein: Sensitization of Tumor Cells to Chemotherapy by the RasGAP 317-326 Sequence Does Not Involve G3BP1
  PloS One. 2011  |   Pubmed ID: 22205990
• Splicing-directed Therapy in a New Mouse Model of Human Accelerated Aging
  Science Translational Medicine. Oct, 2011  |   Pubmed ID: 22030750
• A Conserved Splicing Mechanism of the LMNA Gene Controls Premature Aging
  Human Molecular Genetics. Dec, 2011  |   Pubmed ID: 21875900
• Pro-metastatic Splicing of Ron Proto-oncogene MRNA Can Be Reversed: Therapeutic Potential of Bifunctional Oligonucleotides and Indole Derivatives
  RNA Biology. Jul-Aug, 2010  |   Pubmed ID: 20864806
• The SR Protein B52/SRp55 is Required for DNA Topoisomerase I Recruitment to Chromatin, MRNA Release and Transcription Shutdown
  PLoS Genetics. Sep, 2010  |   Pubmed ID: 20862310
• Exon Definition Complexes Contain the Tri-snRNP and Can Be Directly Converted into B-like Precatalytic Splicing Complexes
  Molecular Cell. Apr, 2010  |   Pubmed ID: 20417601
• Exon-based Clustering of Murine Breast Tumor Transcriptomes Reveals Alternative Exons Whose Expression is Associated with Metastasis
  Cancer Research. Feb, 2010  |   Pubmed ID: 20103641
• Alternative Splicing: Regulation of HIV-1 Multiplication As a Target for Therapeutic Action
  The FEBS Journal. Feb, 2010  |   Pubmed ID: 20082634
• Topoisomerase I Suppresses Genomic Instability by Preventing Interference Between Replication and Transcription
  Nature Cell Biology. Nov, 2009  |   Pubmed ID: 19838172
• Protection Against Retrovirus Pathogenesis by SR Protein Inhibitors
  PloS One. 2009  |   Pubmed ID: 19225570
• Alternative Splicing and Disease
  Biochimica Et Biophysica Acta. Jan, 2009  |   Pubmed ID: 18992329
• A Large Fraction of Unclassified Variants of the Mismatch Repair Genes MLH1 and MSH2 is Associated with Splicing Defects
  Human Mutation. Dec, 2008  |   Pubmed ID: 18561205
• A Novel Role for PA28gamma-proteasome in Nuclear Speckle Organization and SR Protein Trafficking
  Molecular Biology of the Cell. Apr, 2008  |   Pubmed ID: 18256291
• Small-molecule Inhibition of HIV Pre-mRNA Splicing As a Novel Antiretroviral Therapy to Overcome Drug Resistance
  PLoS Pathogens. Oct, 2007  |   Pubmed ID: 17967062
• Inhibition of Nonsense-mediated MRNA Decay (NMD) by a New Chemical Molecule Reveals the Dynamic of NMD Factors in P-bodies
  The Journal of Cell Biology. Sep, 2007  |   Pubmed ID: 17893241
• Eye Development Under the Control of SRp55/B52-mediated Alternative Splicing of Eyeless
  PloS One. 2007  |   Pubmed ID: 17327915
• The SR Family Proteins B52 and DASF/SF2 Modulate Development of the Drosophila Visual System by Regulating Specific RNA Targets
  Molecular and Cellular Biology. Apr, 2007  |   Pubmed ID: 17283056
• SR Proteins As Potential Targets for Therapy
  Progress in Molecular and Subcellular Biology. 2006  |   Pubmed ID: 17076265
• [Alternative Splicing: a Novel Pharmacological Target with Wide Therapeutic Potential]
  Bulletin De L'Académie Nationale De Médecine. May, 2005  |   Pubmed ID: 16433465
• [Selective Modification of Alternative Splicing by Indole Derivatives That Target SR Protein Splicing Factors]
  Médecine Sciences : M/S. Oct, 2005  |   Pubmed ID: 16197888
• Control of Fetal Growth and Neonatal Survival by the RasGAP-associated Endoribonuclease G3BP
  Molecular and Cellular Biology. Oct, 2005  |   Pubmed ID: 16166649
• The Spliceosome: a Novel Multi-faceted Target for Therapy
  Trends in Biochemical Sciences. Aug, 2005  |   Pubmed ID: 16009556
• Selective Modification of Alternative Splicing by Indole Derivatives That Target Serine-arginine-rich Protein Splicing Factors
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2005  |   Pubmed ID: 15939885
• The SR Protein SC35 is Responsible for Aberrant Splicing of the E1alpha Pyruvate Dehydrogenase MRNA in a Case of Mental Retardation with Lactic Acidosis
  Molecular and Cellular Biology. Apr, 2005  |   Pubmed ID: 15798212
• Selective Inhibition of Topoisomerase I and Various Steps of Spliceosome Assembly by Diospyrin Derivatives
  Molecular Pharmacology. Apr, 2005  |   Pubmed ID: 15625279
• A Key Role for Stress-induced Satellite III Transcripts in the Relocalization of Splicing Factors into Nuclear Stress Granules
  Journal of Cell Science. Sep, 2004  |   Pubmed ID: 15331664
• Regulation of Cytoplasmic Stress Granules by Apoptosis-inducing Factor
  Journal of Cell Science. Sep, 2004  |   Pubmed ID: 15316071
• Topoisomerase I and II Inhibitors Control Caspase-2 Pre-messenger RNA Splicing in Human Cells
  Molecular Cancer Research : MCR. Jan, 2004  |   Pubmed ID: 14757846
• Altered Serine/arginine-rich Protein Phosphorylation and Exonic Enhancer-dependent Splicing in Mammalian Cells Lacking Topoisomerase I
  Cancer Research. Dec, 2003  |   Pubmed ID: 14678976
• Resistance to Senescence Induction and Telomere Shortening by a G-quadruplex Ligand Inhibitor of Telomerase
  Cancer Research. Oct, 2003  |   Pubmed ID: 14559794
• Sequence-structure-function Relationships of Tgs1, the Yeast SnRNA/snoRNA Cap Hypermethylase
  Nucleic Acids Research. Aug, 2003  |   Pubmed ID: 12907733
• Interaction Between the Small-nuclear-RNA Cap Hypermethylase and the Spinal Muscular Atrophy Protein, Survival of Motor Neuron
  EMBO Reports. Jun, 2003  |   Pubmed ID: 12776181
• The RasGAP-associated Endoribonuclease G3BP Assembles Stress Granules
  The Journal of Cell Biology. Mar, 2003  |   Pubmed ID: 12642610
• MRNA Degradation Machines in Eukaryotic Cells
  Biochimie. Aug, 2002  |   Pubmed ID: 12457569
• A Conserved Drosophila Transportin-serine/arginine-rich (SR) Protein Permits Nuclear Import of Drosophila SR Protein Splicing Factors and Their Antagonist Repressor Splicing Factor 1
  Molecular Biology of the Cell. Jul, 2002  |   Pubmed ID: 12134081
• Hypermethylation of the Cap Structure of Both Yeast SnRNAs and SnoRNAs Requires a Conserved Methyltransferase That is Localized to the Nucleolus
  Molecular Cell. Apr, 2002  |   Pubmed ID: 11983179