James Howells Central Clinical School, Faculty of Medicine and Health University of Sydney Biography Publications Institution JoVE Articles James Howells has not added a biography. If you are James Howells and would like to personalize this page please email our Author Liaison for assistance. Publications Early Diagnosis of Amyotrophic Lateral Sclerosis by Threshold Tracking and Conventional Transcranial Magnetic Stimulation European Journal of Neurology. Sep, 2021 | Pubmed ID: 34233060 Motor Cortical Excitability Predicts Cognitive Phenotypes in Amyotrophic Lateral Sclerosis Scientific Reports. Jan, 2021 | Pubmed ID: 33500476 Comparison of Figure-of-8 and Circular Coils for Threshold Tracking Transcranial Magnetic Stimulation Measurements Neurophysiologie Clinique = Clinical Neurophysiology. Mar, 2021 | Pubmed ID: 33468370 Electrophysiological Investigation of Motor Axonal Excitability in a Mouse Model of Nerve Constriction Injury Journal of the Peripheral Nervous System : JPNS. 03, 2021 | Pubmed ID: 33432642 Short-interval Intracortical Inhibition As a Function of Inter-stimulus Interval: Three Methods Compared Brain Stimulation. Jan-Feb, 2021 | Pubmed ID: 33166726 Motor Unit Changes in Children with Symptomatic Spinal Muscular Atrophy Treated with Nusinersen Journal of Neurology, Neurosurgery, and Psychiatry. Oct, 2020 | Pubmed ID: 33106369 Neuropathy in Sporadic Inclusion Body Myositis: A Multi-modality Neurophysiological Study Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 11, 2020 | Pubmed ID: 32928695 Acute Changes in Nerve Excitability Following Oxaliplatin Treatment in Mice Journal of Neurophysiology. 07, 2020 | Pubmed ID: 32519566 Interrogating Interneurone Function Using Threshold Tracking of the H Reflex in Healthy Subjects and Patients with Motor Neurone Disease Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 08, 2020 | Pubmed ID: 32336595 Early Focality and Spread of Cortical Dysfunction in Amyotrophic Lateral Sclerosis: A Regional Study Across the Motor Cortices Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 04, 2020 | Pubmed ID: 31959568 The Effect of Coil Type and Limb Dominance in the Assessment of Lower-limb Motor Cortex Excitability Using TMS Neuroscience Letters. 04, 2019 | Pubmed ID: 30710665 Amyotrophic Lateral Sclerosis Diagnostic Index: Toward a Personalized Diagnosis of ALS Neurology. 02, 2019 | Pubmed ID: 30709964 I Contributes to Increased Motoneuron Excitability in Restless Legs Syndrome The Journal of Physiology. 01, 2019 | Pubmed ID: 30430565 Utility of Threshold Tracking Transcranial Magnetic Stimulation in ALS Clinical Neurophysiology Practice. 2018 | Pubmed ID: 30560220 In Vivo Evidence for Reduced Ion Channel Expression in Motor Axons of Patients with Amyotrophic Lateral Sclerosis The Journal of Physiology. 11, 2018 | Pubmed ID: 30175403 Anti-MAG Neuropathy: Role of IgM Antibodies, the Paranodal Junction and Juxtaparanodal Potassium Channels Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 10, 2018 | Pubmed ID: 30144659 A Unified Model of the Excitability of Mouse Sensory and Motor Axons Journal of the Peripheral Nervous System : JPNS. 09, 2018 | Pubmed ID: 29920851 Primary Lateral Sclerosis and the Amyotrophic Lateral Sclerosis-frontotemporal Dementia Spectrum Journal of Neurology. Aug, 2018 | Pubmed ID: 29868980 Physiological Processes Underlying Short Interval Intracortical Facilitation in the Human Motor Cortex Frontiers in Neuroscience. 2018 | Pubmed ID: 29695952 Excitability of Sensory Axons in Amyotrophic Lateral Sclerosis Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 07, 2018 | Pubmed ID: 29661595 Inter-session Reliability of Short-interval Intracortical Inhibition Measured by Threshold Tracking TMS Neuroscience Letters. 05, 2018 | Pubmed ID: 29501687 Tracking Small Sensory Nerve Action Potentials in Human Axonal Excitability Studies Journal of Neuroscience Methods. 03, 2018 | Pubmed ID: 29444448 Neurofascin-155 IGG4 Neuropathy: Pathophysiological Insights, Spectrum of Clinical Severity and Response To Treatment Muscle & Nerve. 05, 2018 | Pubmed ID: 29130507 In vivo Assessment of Neurological Channelopathies: Application of Peripheral Nerve Excitability Studies Neuropharmacology. 04, 2018 | Pubmed ID: 28476643 Motor Unit Remodelling in Multifocal Motor Neuropathy: The Importance of Axonal Loss Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. Oct, 2017 | Pubmed ID: 28837908 Cortical Function and Corticomotoneuronal Adaptation in Monomelic Amyotrophy Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 08, 2017 | Pubmed ID: 28624492 The Evolution of Motor Cortical Dysfunction in Amyotrophic Lateral Sclerosis Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 06, 2017 | Pubmed ID: 28400096 Peripheral Nerve Diffusion Tensor Imaging As a Measure of Disease Progression in ALS Journal of Neurology. May, 2017 | Pubmed ID: 28265751 Diuretic-sensitive Electroneutral Na Movement and Temperature Effects on Central Axons The Journal of Physiology. 06, 2017 | Pubmed ID: 28213919 Burning Pain: Axonal Dysfunction in Erythromelalgia Pain. 05, 2017 | Pubmed ID: 28134657 Differentiating Lower Motor Neuron Syndromes Journal of Neurology, Neurosurgery, and Psychiatry. Jun, 2017 | Pubmed ID: 28003344 Laterality of Motor Cortical Function Measured by Transcranial Magnetic Stimulation Threshold Tracking Muscle & Nerve. 03, 2017 | Pubmed ID: 27511622 Motor Cortical Function Determines Prognosis in Sporadic ALS Neurology. Aug, 2016 | Pubmed ID: 27402895 Effect of Fampridine on Axonal Excitability in Multiple Sclerosis Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. Jul, 2016 | Pubmed ID: 27291883 Threshold Tracking Transcranial Magnetic Stimulation: Effects of Age and Gender on Motor Cortical Function Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 06, 2016 | Pubmed ID: 27178853 Accommodation to Hyperpolarization of Human Axons Assessed in the Frequency Domain Journal of Neurophysiology. 08, 2016 | Pubmed ID: 27098023 In Vivo Evidence of Reduced Nodal and Paranodal Conductances in Type 1 Diabetes Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. Feb, 2016 | Pubmed ID: 26725257 Cortical Function in Asymptomatic Carriers and Patients With C9orf72 Amyotrophic Lateral Sclerosis JAMA Neurology. Nov, 2015 | Pubmed ID: 26348842 Increased HCN Channel Driven Inward Rectification in Benign Cramp Fasciculation Syndrome Brain : a Journal of Neurology. Nov, 2015 | Pubmed ID: 26342125 Sensitivity and Specificity of Threshold Tracking Transcranial Magnetic Stimulation for Diagnosis of Amyotrophic Lateral Sclerosis: a Prospective Study The Lancet. Neurology. May, 2015 | Pubmed ID: 25843898 Axonal Ion Channel Dysfunction in C9orf72 Familial Amyotrophic Lateral Sclerosis JAMA Neurology. Jan, 2015 | Pubmed ID: 25384182 Segmental Motoneuronal Dysfunction is a Feature of Amyotrophic Lateral Sclerosis Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. Apr, 2015 | Pubmed ID: 25220597 Axonal Excitability in X-linked Dominant Charcot Marie Tooth Disease Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. Jun, 2014 | Pubmed ID: 24290847 Evidence for a Causal Relationship Between Hyperkalaemia and Axonal Dysfunction in End-stage Kidney Disease Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. Jan, 2014 | Pubmed ID: 23867066 Excitability and the Safety Margin in Human Axons During Hyperthermia The Journal of Physiology. Jun, 2013 | Pubmed ID: 23613528 Effects of Hemodiafiltration and High Flux Hemodialysis on Nerve Excitability in End-stage Kidney Disease PloS One. 2013 | Pubmed ID: 23536855 The Voltage Dependence of I(h) in Human Myelinated Axons The Journal of Physiology. Apr, 2012 | Pubmed ID: 22310314 Properties of Low-threshold Motor Axons in the Human Median Nerve The Journal of Physiology. Jul, 2010 | Pubmed ID: 20478975 Threshold Behaviour of Human Axons Explored Using Subthreshold Perturbations to Membrane Potential The Journal of Physiology. Jan, 2009 | Pubmed ID: 19047204 Up-regulation of Slow K(+) Channels in Peripheral Motor Axons: a Transcriptional Channelopathy in Multiple Sclerosis Brain : a Journal of Neurology. Nov, 2008 | Pubmed ID: 18697908 Inflections in Threshold Electrotonus to Depolarizing Currents in Sensory Axons Muscle & Nerve. Dec, 2007 | Pubmed ID: 17654562 Plasticity of Inwardly Rectifying Conductances Following a Corticospinal Lesion in Human Subjects The Journal of Physiology. Jun, 2007 | Pubmed ID: 17363389 Outwardly Rectifying Deflections in Threshold Electrotonus Due to K+ Conductances The Journal of Physiology. Apr, 2007 | Pubmed ID: 17272346 Augmentation of the Contraction Force of Human Thenar Muscles by and During Brief Discharge Trains Muscle & Nerve. Mar, 2006 | Pubmed ID: 16435342 After-effects of Near-threshold Stimulation in Single Human Motor Axons The Journal of Physiology. May, 2005 | Pubmed ID: 15746167 Axonal Excitability Measured by Tracking Twitch Contraction Force Muscle & Nerve. Oct, 2004 | Pubmed ID: 15372538 Konventionella och tröskelspårning transkraniella magnetiska stimuleringstester för enhandsdrift Hatice Tankisi1, James Howells2, Bülent Cengiz3, Gintaute Samusyte4, Martin Koltzenburg5, Hugh Bostock6 1Department of Clinical Neurophysiology, Aarhus University Hospital, 2Central Clinical School, Faculty of Medicine and Health, University of Sydney, 3Department of Neurology, Gazi University Faculty of Medicine, 4Department of Neurology, Medical Academy, Lithuanian University of Health Sciences, 5Department of Clinical Neurophysiology, National Hospital for Neurology and Neurosurgery; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, 6Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology JoVE 62787 Neuroscience
Konventionella och tröskelspårning transkraniella magnetiska stimuleringstester för enhandsdrift Hatice Tankisi1, James Howells2, Bülent Cengiz3, Gintaute Samusyte4, Martin Koltzenburg5, Hugh Bostock6 1Department of Clinical Neurophysiology, Aarhus University Hospital, 2Central Clinical School, Faculty of Medicine and Health, University of Sydney, 3Department of Neurology, Gazi University Faculty of Medicine, 4Department of Neurology, Medical Academy, Lithuanian University of Health Sciences, 5Department of Clinical Neurophysiology, National Hospital for Neurology and Neurosurgery; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, 6Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology JoVE 62787 Neuroscience