Jeffrey Parvin Department of Biomedical Informatics The Ohio State University Biography Publications Institution JoVE Articles Jeffrey Parvin has not added a biography. If you are Jeffrey Parvin and would like to personalize this page please email our Author Liaison for assistance. Publications BRCA1 Contributes to Transcription-coupled Repair of DNA Damage Through Polyubiquitination and Degradation of Cockayne Syndrome B Protein Cancer Science. Oct, 2011 | Pubmed ID: 21756275 KIAA0101 Interacts with BRCA1 and Regulates Centrosome Number Molecular Cancer Research : MCR. Aug, 2011 | Pubmed ID: 21673012 Comparing Multiple ChIP-sequencing Experiments Journal of Bioinformatics and Computational Biology. Apr, 2011 | Pubmed ID: 21523932 Fanconi Anemia Protein FANCD2 Inhibits TRF1 PolyADP-ribosylation Through Tankyrase1-dependent Manner Genome Integrity. 2011 | Pubmed ID: 21314979 Histone Deacetylases 9 and 10 Are Required for Homologous Recombination The Journal of Biological Chemistry. Mar, 2011 | Pubmed ID: 21247901 Inference of Hierarchical Regulatory Network of Estrogen-dependent Breast Cancer Through ChIP-based Data BMC Systems Biology. 2010 | Pubmed ID: 21167036 PI 3 Kinase Related Kinases-independent Proteolysis of BRCA1 Regulates Rad51 Recruitment During Genotoxic Stress in Human Cells PloS One. 2010 | Pubmed ID: 21103343 BRCA1 Represses Amphiregulin Gene Expression Cancer Research. Feb, 2010 | Pubmed ID: 20103632 Identification of Breast Tumor Mutations in BRCA1 That Abolish Its Function in Homologous DNA Recombination Cancer Research. Feb, 2010 | Pubmed ID: 20103620 BRCA1/BARD1 E3 Ubiquitin Ligase Can Modify Histones H2A and H2B in the Nucleosome Particle Journal of Biomolecular Structure & Dynamics. Feb, 2010 | Pubmed ID: 19916563 Enabling Data Analysis on High-Throughput Data in Large Data Depository Using Web-Based Analysis Platform - A Case Study on Integrating QUEST with GenePattern in Epigenetics Research Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. Nov, 2009 | Pubmed ID: 21151835 Cdk1 Participates in BRCA1-dependent S Phase Checkpoint Control in Response to DNA Damage Molecular Cell. Aug, 2009 | Pubmed ID: 19683496 Comparative Study on ChIP-seq Data: Normalization and Binding Pattern Characterization Bioinformatics (Oxford, England). Sep, 2009 | Pubmed ID: 19561022 The BRCA1-dependent Ubiquitin Ligase, Gamma-tubulin, and Centrosomes Environmental and Molecular Mutagenesis. Oct, 2009 | Pubmed ID: 19274767 Regulation of Centrosomes by the BRCA1-dependent Ubiquitin Ligase Cancer Biology & Therapy. Oct, 2008 | Pubmed ID: 18927495 Multiple Mechanisms Contribute to Inhibit Transcription in Response to DNA Damage The Journal of Biological Chemistry. Apr, 2008 | Pubmed ID: 18281289 BRCA1 Regulates Gamma-tubulin Binding to Centrosomes Cancer Biology & Therapy. Dec, 2007 | Pubmed ID: 18087219 Aurora-A Kinase Regulates Breast Cancer Associated Gene 1 Inhibition of Centrosome-dependent Microtubule Nucleation Cancer Research. Dec, 2007 | Pubmed ID: 18056443 Network Modeling Links Breast Cancer Susceptibility and Centrosome Dysfunction Nature Genetics. Nov, 2007 | Pubmed ID: 17922014 BRCA1 Control of Steroid Receptor Ubiquitination Science's STKE : Signal Transduction Knowledge Environment. Jun, 2007 | Pubmed ID: 17579243 A Mechanism for Transcriptional Repression Dependent on the BRCA1 E3 Ubiquitin Ligase Proceedings of the National Academy of Sciences of the United States of America. Apr, 2007 | Pubmed ID: 17420471 The BRCA1 E3 Ubiquitin Ligase Controls Centrosome Dynamics Cell Cycle (Georgetown, Tex.). Sep, 2006 | Pubmed ID: 16969086 Alpha-synuclein Acts in the Nucleus to Inhibit Histone Acetylation and Promote Neurotoxicity Human Molecular Genetics. Oct, 2006 | Pubmed ID: 16959795 Centrosome Function in Normal and Tumor Cells Journal of Cellular Biochemistry. Dec, 2006 | Pubmed ID: 16817224 Oncoprotein EWS-FLI1 Activity is Enhanced by RNA Helicase A Cancer Research. Jun, 2006 | Pubmed ID: 16740692 Identification of Domains of BRCA1 Critical for the Ubiquitin-dependent Inhibition of Centrosome Function Cancer Research. Apr, 2006 | Pubmed ID: 16618730 BRCA1 DNA-binding Activity is Stimulated by BARD1 Cancer Research. Feb, 2006 | Pubmed ID: 16489000 Substrates of the BRCA1-dependent Ubiquitin Ligase Cancer Biology & Therapy. Feb, 2006 | Pubmed ID: 16479151 Direct Stimulation of Transcription Initiation by BRCA1 Requires Both Its Amino and Carboxyl Termini The Journal of Biological Chemistry. Mar, 2006 | Pubmed ID: 16473884 Recruitment of ORC or CDC6 to DNA is Sufficient to Create an Artificial Origin of Replication in Mammalian Cells Genes & Development. Dec, 2005 | Pubmed ID: 16322558 Centrosomal Microtubule Nucleation Activity is Inhibited by BRCA1-dependent Ubiquitination Molecular and Cellular Biology. Oct, 2005 | Pubmed ID: 16166645 BRCA1/BARD1 Ubiquitinate Phosphorylated RNA Polymerase II The Journal of Biological Chemistry. Jul, 2005 | Pubmed ID: 15886201 Degradation of Cdt1 During S Phase is Skp2-independent and is Required for Efficient Progression of Mammalian Cells Through S Phase The Journal of Biological Chemistry. Jun, 2005 | Pubmed ID: 15855168 Direct DNA Binding Activity of the Fanconi Anemia D2 Protein The Journal of Biological Chemistry. Jun, 2005 | Pubmed ID: 15849361 The Tumor Suppressor Protein P53 Functions Similarly to P63 and P73 in Activating Transcription in Vitro Cancer Biology & Therapy. Apr, 2005 | Pubmed ID: 15846087 BRCA1-dependent Ubiquitination of Gamma-tubulin Regulates Centrosome Number Molecular and Cellular Biology. Oct, 2004 | Pubmed ID: 15367667 Overview of History and Progress in BRCA1 Research: the First BRCA1 Decade Cancer Biology & Therapy. Jun, 2004 | Pubmed ID: 15197353 A Unified Nomenclature for Protein Subunits of Mediator Complexes Linking Transcriptional Regulators to RNA Polymerase II Molecular Cell. Jun, 2004 | Pubmed ID: 15175151 Expression of an Amino-terminal BRCA1 Deletion Mutant Causes a Dominant Growth Inhibition in MCF10A Cells Oncogene. Jul, 2004 | Pubmed ID: 15122325 Phosphorylation of Histone H2A Inhibits Transcription on Chromatin Templates The Journal of Biological Chemistry. May, 2004 | Pubmed ID: 15010469 Elongation by RNA Polymerase II on Chromatin Templates Requires Topoisomerase Activity Nucleic Acids Research. Sep, 2003 | Pubmed ID: 12930951 Transcription from the Perspective of the DNA: Twists and Bumps in the Road Critical Reviews in Eukaryotic Gene Expression. 2003 | Pubmed ID: 12839093 The Multiple Nuclear Functions of BRCA1: Transcription, Ubiquitination and DNA Repair Current Opinion in Cell Biology. Jun, 2003 | Pubmed ID: 12787778 Overexpression of a Protein Fragment of RNA Helicase A Causes Inhibition of Endogenous BRCA1 Function and Defects in Ploidy and Cytokinesis in Mammary Epithelial Cells Oncogene. Feb, 2003 | Pubmed ID: 12592385 Creating a Tool-kit for Exploring BRCA1 Function Cancer Biology & Therapy. Sep-Oct, 2002 | Pubmed ID: 12496478 The BRCA1 and BARD1 Association with the RNA Polymerase II Holoenzyme Cancer Research. Aug, 2002 | Pubmed ID: 12154023 Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1 Jeffrey Parvin1, Natsuko Chiba2, Derek Ransburgh1 1Department of Biomedical Informatics, The Ohio State University, 2Departments of Molecular Immunology and Clinical Oncology, Tohoku University JoVE 2468 Biology
Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1 Jeffrey Parvin1, Natsuko Chiba2, Derek Ransburgh1 1Department of Biomedical Informatics, The Ohio State University, 2Departments of Molecular Immunology and Clinical Oncology, Tohoku University JoVE 2468 Biology