Job Dekker Department of Systems Biology University of Massachusetts Medical School Biography Publications Institution JoVE Articles Job Dekker has not added a biography. If you are Job Dekker and would like to personalize this page please email our Author Liaison for assistance. Publications Multiscale Reorganization of the Genome Following DNA Damage Facilitates Chromosome Translocations Via Nuclear Actin Polymerization Nature Structural & Molecular Biology. Jan, 2023 | Pubmed ID: 36564591 Diverse Silent Chromatin States Modulate Genome Compartmentalization and Loop Extrusion Barriers Nature Structural & Molecular Biology. Jan, 2023 | Pubmed ID: 36550219 A Cohesin Traffic Pattern Genetically Linked to Gene Regulation Nature Structural & Molecular Biology. Dec, 2022 | Pubmed ID: 36482254 Regulation of the Mitotic Chromosome Folding Machines The Biochemical Journal. Oct, 2022 | Pubmed ID: 36268993 CTCF-CTCF Loops and Intra-TAD Interactions Show Differential Dependence on Cohesin Ring Integrity Nature Cell Biology. Oct, 2022 | Pubmed ID: 36202971 Nutritional Control Regulates Symbiont Proliferation and Life History in Coral-dinoflagellate Symbiosis BMC Biology. May, 2022 | Pubmed ID: 35549698 Author Correction: Expanded Encyclopaedias of DNA Elements in the Human and Mouse Genomes Nature. May, 2022 | Pubmed ID: 35474001 Loops, Topologically Associating Domains, Compartments, and Territories Are Elastic and Robust to Dramatic Nuclear Volume Swelling Scientific Reports. Mar, 2022 | Pubmed ID: 35304523 Spatial Organization of Transcribed Eukaryotic Genes Nature Cell Biology. Mar, 2022 | Pubmed ID: 35177821 Mechanisms of Chromosome Folding and Nuclear Organization: Their Interplay and Open Questions Cold Spring Harbor Perspectives in Biology. Jul, 2022 | Pubmed ID: 34518339 Inner Nuclear Protein Matrin-3 Coordinates Cell Differentiation by Stabilizing Chromatin Architecture Nature Communications. Oct, 2021 | Pubmed ID: 34716321 Symbiodinium Microadriaticum (coral Microalgal Endosymbiont) Trends in Genetics : TIG. Nov, 2021 | Pubmed ID: 34518054 Systematic Evaluation of Chromosome Conformation Capture Assays Nature Methods. Sep, 2021 | Pubmed ID: 34480151 Linker Histone H1.8 Inhibits Chromatin Binding of Condensins and DNA Topoisomerase II to Tune Chromosome Length and Individualization ELife. Aug, 2021 | Pubmed ID: 34406118 Hi-C 3.0: Improved Protocol for Genome-Wide Chromosome Conformation Capture Current Protocols. Jul, 2021 | Pubmed ID: 34286910 Chromosome-Level Assembly of the Atlantic Silverside Genome Reveals Extreme Levels of Sequence Diversity and Structural Genetic Variation Genome Biology and Evolution. Jun, 2021 | Pubmed ID: 33964136 Genetic and Spatial Organization of the Unusual Chromosomes of the Dinoflagellate Symbiodinium Microadriaticum Nature Genetics. May, 2021 | Pubmed ID: 33927399 Liquid Chromatin Hi-C Characterizes Compartment-dependent Chromatin Interaction Dynamics Nature Genetics. Mar, 2021 | Pubmed ID: 33574602 Cohesin Mutations Alter DNA Damage Repair and Chromatin Structure and Create Therapeutic Vulnerabilities in MDS/AML JCI Insight. Feb, 2021 | Pubmed ID: 33351783 Is Involved in Corneal Stroma Development by Regulating Neural Crest Migration International Journal of Molecular Sciences. Oct, 2020 | Pubmed ID: 33096935 Detecting Chromatin Interactions Between and Along Sister Chromatids with SisterC Nature Methods. Oct, 2020 | Pubmed ID: 32968250 Clustering of Strong Replicators Associated with Active Promoters is Sufficient to Establish an Early-replicating Domain The EMBO Journal. Nov, 2020 | Pubmed ID: 32935369 Multi-contact 3C Reveals That the Human Genome During Interphase is Largely Not Entangled Nature Structural & Molecular Biology. Dec, 2020 | Pubmed ID: 32929283 Large Domains of Heterochromatin Direct the Formation of Short Mitotic Chromosome Loops ELife. Sep, 2020 | Pubmed ID: 32915140 Expanded Encyclopaedias of DNA Elements in the Human and Mouse Genomes Nature. Jul, 2020 | Pubmed ID: 32728249 Mechanisms and Functions of Chromosome Compartmentalization Trends in Biochemical Sciences. May, 2020 | Pubmed ID: 32311333 Ultrastructural Details of Mammalian Chromosome Architecture Molecular Cell. May, 2020 | Pubmed ID: 32213324 SPEN Integrates Transcriptional and Epigenetic Control of X-inactivation Nature. 02, 2020 | Pubmed ID: 32025035 Transcriptional Silencers in Drosophila Serve a Dual Role As Transcriptional Enhancers in Alternate Cellular Contexts Molecular Cell. Jan, 2020 | Pubmed ID: 31704182 A Chromosome Folding Intermediate at the Condensin-to-cohesin Transition During Telophase Nature Cell Biology. Nov, 2019 | Pubmed ID: 31685986 Highly Structured Homolog Pairing Reflects Functional Organization of the Drosophila Genome Nature Communications. Oct, 2019 | Pubmed ID: 31582763 The Genome-wide Multi-layered Architecture of Chromosome Pairing in Early Drosophila Embryos Nature Communications. Oct, 2019 | Pubmed ID: 31582744 Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation Cell Stem Cell. Nov, 2019 | Pubmed ID: 31495782 Publisher Correction: Heterochromatin Drives Compartmentalization of Inverted and Conventional Nuclei Nature. Aug, 2019 | Pubmed ID: 31375785 Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance Between Replication Timing and Chromatin Compartment Stem Cell Reports. Jul, 2019 | Pubmed ID: 31231024 Heterochromatin Drives Compartmentalization of Inverted and Conventional Nuclei Nature. Jun, 2019 | Pubmed ID: 31168090 Measuring the Reproducibility and Quality of Hi-C Data Genome Biology. Mar, 2019 | Pubmed ID: 30890172 Extensive Heterogeneity and Intrinsic Variation in Spatial Genome Organization Cell. Mar, 2019 | Pubmed ID: 30799036 CTCF Sites Display Cell Cycle-dependent Dynamics in Factor Binding and Nucleosome Positioning Genome Research. Feb, 2019 | Pubmed ID: 30655336 The Non-canonical SMC Protein SmcHD1 Antagonises TAD Formation and Compartmentalisation on the Inactive X Chromosome Nature Communications. Jan, 2019 | Pubmed ID: 30604745 Higher-Order Organization Principles of Pre-translational MRNPs Molecular Cell. Nov, 2018 | Pubmed ID: 30415953 Single-allele Chromatin Interactions Identify Regulatory Hubs in Dynamic Compartmentalized Domains Nature Genetics. Dec, 2018 | Pubmed ID: 30374068 Integrative Detection and Analysis of Structural Variation in Cancer Genomes Nature Genetics. Oct, 2018 | Pubmed ID: 30202056 CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia Cell. Jun, 2018 | Pubmed ID: 29958106 C-BERST: Defining Subnuclear Proteomic Landscapes at Genomic Elements with DCas9-APEX2 Nature Methods. Jun, 2018 | Pubmed ID: 29735996 A Pathway for Mitotic Chromosome Formation Science (New York, N.Y.). Feb, 2018 | Pubmed ID: 29348367 The Cluster is a Dynamic and Resilient TAD Boundary Controlling the Segregation of Antagonistic Regulatory Landscapes Genes & Development. Nov, 2017 | Pubmed ID: 29273679 The 4D Nucleome Project Nature. 09, 2017 | Pubmed ID: 28905911 SMC Complexes Differentially Compact Mitotic Chromosomes According to Genomic Context Nature Cell Biology. Sep, 2017 | Pubmed ID: 28825700 Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization Cell. May, 2017 | Pubmed ID: 28525758 Shelterin Components Mediate Genome Reorganization in Response to Replication Stress Proceedings of the National Academy of Sciences of the United States of America. May, 2017 | Pubmed ID: 28490498 Hi-C 2.0: An Optimized Hi-C Procedure for High-resolution Genome-wide Mapping of Chromosome Conformation Methods (San Diego, Calif.). Jul, 2017 | Pubmed ID: 28435001 Epigenetic Characteristics of the Mitotic Chromosome in 1D and 3D Critical Reviews in Biochemistry and Molecular Biology. Apr, 2017 | Pubmed ID: 28228067 Polycomb Repressive Complex 1 Generates Discrete Compacted Domains That Change During Differentiation Molecular Cell. Feb, 2017 | Pubmed ID: 28157505 CTCF-mediated Topological Boundaries During Development Foster Appropriate Gene Regulation Genes & Development. 12, 2016 | Pubmed ID: 28087711 Mapping the 3D Genome: Aiming for Consilience Nature Reviews. Molecular Cell Biology. Nov, 2016 | Pubmed ID: 27869158 Crystal Structure of the DNA Binding Domain of the Transcription Factor T-bet Suggests Simultaneous Recognition of Distant Genome Sites Proceedings of the National Academy of Sciences of the United States of America. Oct, 2016 | Pubmed ID: 27791029 RUNX1 Contributes to Higher-order Chromatin Organization and Gene Regulation in Breast Cancer Cells Biochimica Et Biophysica Acta. Nov, 2016 | Pubmed ID: 27514584 Structural Organization of the Inactive X Chromosome in the Mouse Nature. Jul, 2016 | Pubmed ID: 27437574 SMARCA4 Regulates Gene Expression and Higher-order Chromatin Structure in Proliferating Mammary Epithelial Cells Genome Research. Sep, 2016 | Pubmed ID: 27435934 Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma American Journal of Respiratory and Critical Care Medicine. Dec, 2016 | Pubmed ID: 27367781 Local Genome Topology Can Exhibit an Incompletely Rewired 3D-Folding State During Somatic Cell Reprogramming Cell Stem Cell. May, 2016 | Pubmed ID: 27152443 TAD Disruption As Oncogenic Driver Current Opinion in Genetics & Development. Feb, 2016 | Pubmed ID: 27111891 The 3D Genome As Moderator of Chromosomal Communication Cell. Mar, 2016 | Pubmed ID: 26967279 Activation of Proto-oncogenes by Disruption of Chromosome Neighborhoods Science (New York, N.Y.). Mar, 2016 | Pubmed ID: 26940867 Extremely Long-Range Chromatin Loops Link Topological Domains to Facilitate a Diverse Antibody Repertoire Cell Reports. Feb, 2016 | Pubmed ID: 26804913 Invariant TAD Boundaries Constrain Cell-Type-Specific Looping Interactions Between Promoters and Distal Elements Around the CFTR Locus American Journal of Human Genetics. Jan, 2016 | Pubmed ID: 26748519 The Conformation of Yeast Chromosome III Is Mating Type Dependent and Controlled by the Recombination Enhancer Cell Reports. Dec, 2015 | Pubmed ID: 26655901 HiC-Pro: an Optimized and Flexible Pipeline for Hi-C Data Processing Genome Biology. 2015 | Pubmed ID: 26619908 High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex Across the X Chromosome in Drosophila Molecular Cell. Oct, 2015 | Pubmed ID: 26431028 Long-Range Chromatin Interactions Cold Spring Harbor Perspectives in Biology. Oct, 2015 | Pubmed ID: 26430217 Chromatin Interaction Analysis Reveals Changes in Small Chromosome and Telomere Clustering Between Epithelial and Breast Cancer Cells Genome Biology. Sep, 2015 | Pubmed ID: 26415882 Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells Cell. Sep, 2015 | Pubmed ID: 26365489 Structural and Functional Diversity of Topologically Associating Domains FEBS Letters. Oct, 2015 | Pubmed ID: 26348399 Condensin Promotes the Juxtaposition of DNA Flanking Its Loading Site in Bacillus Subtilis Genes & Development. Aug, 2015 | Pubmed ID: 26253537 The Yeast Genome Undergoes Significant Topological Reorganization in Quiescence Nucleic Acids Research. Sep, 2015 | Pubmed ID: 26202961 Measuring Chromatin Structure in Budding Yeast Cold Spring Harbor Protocols. Jul, 2015 | Pubmed ID: 26134912 Hi-C in Budding Yeast Cold Spring Harbor Protocols. Jul, 2015 | Pubmed ID: 26134906 Mapping Nucleosome Resolution Chromosome Folding in Yeast by Micro-C Cell. Jul, 2015 | Pubmed ID: 26119342 Chromosome Conformation Capture Carbon Copy (5C) in Budding Yeast Cold Spring Harbor Protocols. Jun, 2015 | Pubmed ID: 26034306 Randomized Ligation Control for Chromosome Conformation Capture Cold Spring Harbor Protocols. Jun, 2015 | Pubmed ID: 26034305 Chromosome Conformation Capture (3C) in Budding Yeast Cold Spring Harbor Protocols. Jun, 2015 | Pubmed ID: 26034304 Condensin-driven Remodelling of X Chromosome Topology During Dosage Compensation Nature. Jul, 2015 | Pubmed ID: 26030525 Spatial Enhancer Clustering and Regulation of Enhancer-proximal Genes by Cohesin Genome Research. Apr, 2015 | Pubmed ID: 25677180 The Hitchhiker's Guide to Hi-C Analysis: Practical Guidelines Methods (San Diego, Calif.). Jan, 2015 | Pubmed ID: 25448293 Two Ways to Fold the Genome During the Cell Cycle: Insights Obtained with Chromosome Conformation Capture Epigenetics & Chromatin. 2014 | Pubmed ID: 25435919 Cohesin-dependent Globules and Heterochromatin Shape 3D Genome Architecture in S. Pombe Nature. Dec, 2014 | Pubmed ID: 25307058 Reply to Brunet and Doolittle: Both Selected Effect and Causal Role Elements Can Influence Human Biology and Disease Proceedings of the National Academy of Sciences of the United States of America. Aug, 2014 | Pubmed ID: 25275169 Predictive Polymer Modeling Reveals Coupled Fluctuations in Chromosome Conformation and Transcription Cell. May, 2014 | Pubmed ID: 24813616 Defining Functional DNA Elements in the Human Genome Proceedings of the National Academy of Sciences of the United States of America. Apr, 2014 | Pubmed ID: 24753594 High-throughput Genome Scaffolding from in Vivo DNA Interaction Frequency Nature Biotechnology. Dec, 2013 | Pubmed ID: 24270850 Flexible Ordering of Antibody Class Switch and V(D)J Joining During B-cell Ontogeny Genes & Development. Nov, 2013 | Pubmed ID: 24240234 Organization of the Mitotic Chromosome Science (New York, N.Y.). Nov, 2013 | Pubmed ID: 24200812 Cohesin-based Chromatin Interactions Enable Regulated Gene Expression Within Preexisting Architectural Compartments Genome Research. Dec, 2013 | Pubmed ID: 24002784 Architectural Protein Subclasses Shape 3D Organization of Genomes During Lineage Commitment Cell. Jun, 2013 | Pubmed ID: 23706625 Exploring the Three-dimensional Organization of Genomes: Interpreting Chromatin Interaction Data Nature Reviews. Genetics. Jun, 2013 | Pubmed ID: 23657480 Nuclear Biology: What's Been Most Surprising? Cell. Mar, 2013 | Pubmed ID: 23616995 The Hierarchy of the 3D Genome Molecular Cell. Mar, 2013 | Pubmed ID: 23473598 Correlated Alterations in Genome Organization, Histone Methylation, and DNA-lamin A/C Interactions in Hutchinson-Gilford Progeria Syndrome Genome Research. Feb, 2013 | Pubmed ID: 23152449 3C-based Technologies to Study the Shape of the Genome Methods (San Diego, Calif.). Nov, 2012 | Pubmed ID: 23199640 From Cells to Chromatin: Capturing Snapshots of Genome Organization with 5C Technology Methods (San Diego, Calif.). Nov, 2012 | Pubmed ID: 23137922 The Long-range Interaction Landscape of Gene Promoters Nature. Sep, 2012 | Pubmed ID: 22955621 The Accessible Chromatin Landscape of the Human Genome Nature. Sep, 2012 | Pubmed ID: 22955617 Iterative Correction of Hi-C Data Reveals Hallmarks of Chromosome Organization Nature Methods. Oct, 2012 | Pubmed ID: 22941365 HiTC: Exploration of High-throughput 'C' Experiments Bioinformatics (Oxford, England). Nov, 2012 | Pubmed ID: 22923296 Analysis of Long-range Chromatin Interactions Using Chromosome Conformation Capture Methods (San Diego, Calif.). Nov, 2012 | Pubmed ID: 22903059 マウス DNA 要素 (エンコード) マウスの百科事典。 Genome Biology. Aug, 2012 | Pubmed ID: 22889292 Hi-C: a Comprehensive Technique to Capture the Conformation of Genomes Methods (San Diego, Calif.). Nov, 2012 | Pubmed ID: 22652625 CTCF and Cohesin Help Neurons Raise Their Self-awareness Proceedings of the National Academy of Sciences of the United States of America. Jun, 2012 | Pubmed ID: 22615386 MORC Family ATPases Required for Heterochromatin Condensation and Gene Silencing Science (New York, N.Y.). Jun, 2012 | Pubmed ID: 22555433 The Context of Gene Expression Regulation F1000 Biology Reports. 2012 | Pubmed ID: 22500194 Spatial Partitioning of the Regulatory Landscape of the X-inactivation Centre Nature. May, 2012 | Pubmed ID: 22495304 Spatial Organization of the Mouse Genome and Its Role in Recurrent Chromosomal Translocations Cell. Mar, 2012 | Pubmed ID: 22341456 ひと細胞におけるキメラ Rna 転写ネットワークのための証拠で構成。 PloS One. 2012 | Pubmed ID: 22238572 構造とクロマチンと染色体機能。 Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2012 | Pubmed ID: 22174298 高スループット遺伝子を中心とした規制ネットワークのマッピングのための酵母 1 ハイブリッド試金を強化しました。 Nature Methods. Dec, 2011 | Pubmed ID: 22037705 遺伝子を中心とした人間の遺伝子制御ネットワークマッピングのための酵母ワンハイブリッドアッセイ Nature Methods. Dec, 2011 | Pubmed ID: 22037702 細菌ゲノムと遺伝子摂動による変質作用の三次元のアーキテクチャです。 Molecular Cell. Oct, 2011 | Pubmed ID: 22017872 転流マッピング B 細胞のリスキーなライフ スタイルを公開します。 Cell. Sep, 2011 | Pubmed ID: 21962501 クロマチン球: 高次染色体構造の一般的なモチーフですか? Current Opinion in Cell Biology. Jun, 2011 | Pubmed ID: 21489772 A Long Noncoding RNA Maintains Active Chromatin to Coordinate Homeotic Gene Expression Nature. Apr, 2011 | Pubmed ID: 21423168 折り畳み式三次元の α グロビン遺伝子ドメインのクロマチン球の形成を明らかにします。 Nature Structural & Molecular Biology. Jan, 2011 | Pubmed ID: 21131981 姉妹の凝集度と構造軸コンポーネント減数分裂組み換えの相同物バイアスを仲介します。 Cell. Dec, 2010 | Pubmed ID: 21145459 解明の染色体のアーキテクチャ用のゲノミクスのツールです。 Nature Biotechnology. Oct, 2010 | Pubmed ID: 20944601 メディエーターとコヒーシンが遺伝子発現とクロマチン構造を接続します。 Nature. Sep, 2010 | Pubmed ID: 20720539 化学遺伝の作戦を識別ヒストンデアセチラーゼ 1 (HDAC1) と鎌状赤血球病の治療標的としての HDAC2。 Proceedings of the National Academy of Sciences of the United States of America. Jul, 2010 | Pubmed ID: 20616024 ゲノムの 1 次元および 3次元マップを統合します。 Journal of Cell Science. Jun, 2010 | Pubmed ID: 20519580 細胞タイプ特異長距離ループの相互作用は CFTR 遺伝子の遠い規制要素を識別します。 Nucleic Acids Research. Jul, 2010 | Pubmed ID: 20360044 長距離相互作用の包括的なマッピングは、ヒトゲノムの折りたたみの原理を明らかに Science (New York, N.Y.). Oct, 2009 | Pubmed ID: 19815776 My5C: Web ツール染色体立体構造の研究をキャプチャします。 Nature Methods. Oct, 2009 | Pubmed ID: 19789528 5 C 技術を使用して大規模なゲノム領域の空間クロマチン組織を決定します。 Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19588094 疾患を引き起こす 7.4 Kb 中断 Cis 規制削除保存非コーディング シーケンスと FOXL2 の発がんプロモーターとの相互作用: 変異のスクリーニングのための含意。 PLoS Genetics. Jun, 2009 | Pubmed ID: 19543368 遺伝子の日付は、締約国とGalas。クロマチン動態と高次機構シンポジウム EMBO Reports. Jul, 2009 | Pubmed ID: 19525922 酵母サイレント交配型遺伝子座はサイレンサー タンパク質依存型長距離相互作用を通じてヘテロクロマチンの集りを形作る。 PLoS Genetics. May, 2009 | Pubmed ID: 19424429 DNA 二重鎖切断核周囲に局在を調節するメカニズム。 Genes & Development. Apr, 2009 | Pubmed ID: 19390086 染色体のコンホメーションのキャプチャ (3 C) を使用して Cis、trans クロマチン間相互作用ネットワークのマッピング。 Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 18951182 長距離染色体相互作用と遺伝子発現制御。 Molecular BioSystems. Nov, 2008 | Pubmed ID: 18931780 酵母における in Vivo でのクロマチンの相互作用をマッピング拡張クロマチンファイバー締固めの広域的変化を示唆しています。 The Journal of Biological Chemistry. Dec, 2008 | Pubmed ID: 18930918 3 番目の次元での遺伝子の規則。 Science (New York, N.Y.). Mar, 2008 | Pubmed ID: 18369139 イカロス出版規制人間グロビン遺伝子の切り替えのための機構です。 British Journal of Haematology. May, 2008 | Pubmed ID: 18318763 染色体構造キャプチャ カーボン コピー技術。 Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [et Al.]. Oct, 2007 | Pubmed ID: 18265398 ポリコーム応答要素は、複雑な Bithorax の染色体高次構造形成を仲介します。 Nature Cell Biology. Oct, 2007 | Pubmed ID: 17828248 染色体のコンホメーションのキャプチャ アッセイ (3 C QPCR) の定量分析。 Nature Protocols. 2007 | Pubmed ID: 17641637 GC と AT-豊富なクロマチンのドメインは、コンフォメーションとヒストンの修正状態で異なる、特異的 Rpd3p によってモジュレートされます。 Genome Biology. 2007 | Pubmed ID: 17577398 、ENCODEパイロットプロジェクトによるヒトゲノムの1%の機能要素の同定と解析 Nature. Jun, 2007 | Pubmed ID: 17571346 ネットワークの物理的な相互作用 5 C 技術を使用してゲノムの要素間のマッピング。 Nature Protocols. 2007 | Pubmed ID: 17446898 クロマチンの相互作用によって染色体のコンホメーション キャプチャ マッピング。 Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [et Al.]. May, 2006 | Pubmed ID: 18265379 染色体構造をキャプチャ カーボン コピー (5 C): ゲノムの要素間の相互作用のマッピングのための超並列ソリューション。 Genome Research. Oct, 2006 | Pubmed ID: 16954542 アクティブ FMR1 プロモーターは変えられた Chromatin のコンフォメーションと埋め込まれたローカル ヒストン修飾の大規模なドメインに関連付けられます。 Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16891414 3 つの 'C' S の染色体のコンホメーションのキャプチャ: コントロールは、コントロール、コントロール。 Nature Methods. Jan, 2006 | Pubmed ID: 16369547 Β-グロビン座位におけるで遠い規制要素中の近接潟 1 霧 1 が必要です。 Molecular Cell. Feb, 2005 | Pubmed ID: 15694345 染色体機能の力学的根拠。 Proceedings of the National Academy of Sciences of the United States of America. Aug, 2004 | Pubmed ID: 15299144 長距離染色体相互作用の詳しく見て。 Trends in Biochemical Sciences. Jun, 2003 | Pubmed ID: 12826398 染色体のコンホメーションをキャプチャします。 Science (New York, N.Y.). Feb, 2002 | Pubmed ID: 11847345 長さスケール全体で染色体コンフォメーションをキャプチャする Liyan Yang1, Betul Akgol Oksuz1, Job Dekker1,2, Johan Harmen Gibcus1 1Department of Systems Biology, University of Massachusetts Medical School, 2Howard Hughes Medical Institute JoVE 64001 Genetics ハイC:ゲノムの三次元構造を研究する方法。 Nynke L. van Berkum*1, Erez Lieberman-Aiden*2,3,4,5, Louise Williams*2, Maxim Imakaev6, Andreas Gnirke2, Leonid A. Mirny3,6, Job Dekker1, Eric S. Lander2,7,8 1Program in Gene Function and Expression, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 2Broad Institute of Harvard and Massachusetts Institute of Technology, 3Division of Health Sciences and Technology, Massachusetts Institute of Technology, 4Program for Evolutionary Dynamics, Department of Organismic and Evolutionary Biology, Department of Mathematics, Harvard University, 5Department of Applied Mathematics, Harvard University, 6Department of Physics, Massachusetts Institute of Technology, 7Department of Systems Biology, Harvard Medical School, 8Department of Biology, Massachusetts Institute of Technology JoVE 1869 Biology
長さスケール全体で染色体コンフォメーションをキャプチャする Liyan Yang1, Betul Akgol Oksuz1, Job Dekker1,2, Johan Harmen Gibcus1 1Department of Systems Biology, University of Massachusetts Medical School, 2Howard Hughes Medical Institute JoVE 64001 Genetics
ハイC:ゲノムの三次元構造を研究する方法。 Nynke L. van Berkum*1, Erez Lieberman-Aiden*2,3,4,5, Louise Williams*2, Maxim Imakaev6, Andreas Gnirke2, Leonid A. Mirny3,6, Job Dekker1, Eric S. Lander2,7,8 1Program in Gene Function and Expression, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 2Broad Institute of Harvard and Massachusetts Institute of Technology, 3Division of Health Sciences and Technology, Massachusetts Institute of Technology, 4Program for Evolutionary Dynamics, Department of Organismic and Evolutionary Biology, Department of Mathematics, Harvard University, 5Department of Applied Mathematics, Harvard University, 6Department of Physics, Massachusetts Institute of Technology, 7Department of Systems Biology, Harvard Medical School, 8Department of Biology, Massachusetts Institute of Technology JoVE 1869 Biology